Abstract
Niche has become the most important issue in stem cell biology, but it is still a hypothetical notion that cannot be defined in a better way than the microenvironment surrounding stem cells. Using a melanocyte stem cell system as a model, we have analyzed the cellular and molecular requirements for differentiation of quiescent stem cells. Our results demonstrate the multiple subsets within the stem cell compartment and thus suggests the complexity of niche.
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© 2006 Springer-Verlag Berlin Heidelberg
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Nishikawa, S.I., Osawa, M. (2006). What Is a Stem Cell Niche?. In: Morser, J., Nishikawa, S.I., Schöler, H.R. (eds) Stem Cells in Reproduction and in the Brain. Ernst Schering Research Foundation Workshop, vol 60. Springer, Berlin, Heidelberg . https://doi.org/10.1007/3-540-31437-7_1
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DOI: https://doi.org/10.1007/3-540-31437-7_1
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-31436-3
Online ISBN: 978-3-540-31437-0
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