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FNAC Technique and Slide Preparation

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References

  1. Balicer RD, Fadlon J. The information age and its effect on the doctor-patient relationship. Harefuah 2004;143(10):749–52, 764

    PubMed  Google Scholar 

  2. Feld AD. Informed consent: not just for procedures anymore. Am J Gastroenterol 2004;99(6):977–80

    Article  PubMed  Google Scholar 

  3. Kuczewski MG, Marshall P. The decision dynamics of clinical research: the context and process of informed consent. Med Care 2002;40(9 Suppl): V45–54

    PubMed  Google Scholar 

  4. Cericola SA. Understanding informed consent. Plast Surg Nurs 1998;18(4):249–51

    CAS  PubMed  Google Scholar 

  5. Gasparini G, Boniello R, Longobardi G, Pelo S. Orthognathic surgery: an informed consent model. J Craniofac Surg 2004;15(5):858–62

    PubMed  Google Scholar 

  6. Pereira SP, Hussaini SH, Wilkinson ML. Informed consent for upper gastrointestinal endoscopy. Gut 1995;37(1):151–3

    CAS  PubMed  Google Scholar 

  7. Pape T. Legal and ethical considerations of informed consent. AORN J 1997;65(6):1122–7

    CAS  PubMed  Google Scholar 

  8. White CS, Mason AC, Feehan M, Templeton PA. Informed consent for percutaneous lung biopsy: comparison of two consent protocols based on patient recall after the procedure. AJR Am J Roentgenol 1995;165(5): 1139–42

    CAS  PubMed  Google Scholar 

  9. Plaut EA. The ethics of informed consent: an overview. Psychiatr J Univ Ott 1989;14(3):435–8

    CAS  PubMed  Google Scholar 

  10. Newton-Howes PA, Bedford ND, Dobbs BR, Frizelle FA. Informed consent: what do patients want to know? N Z Med J 1998;111(1073):340–2

    CAS  PubMed  Google Scholar 

  11. Mullenix PS, Carter PL, Martin MJ, Steele SR, Scott CL, Walts MJ, et al. Predictive value of intraoperative touch preparation analysis of sentinel lymph nodes for axillary metastasis in breast cancer. Am J Surg 2003;185(5):420–4

    PubMed  Google Scholar 

  12. Perez-Moreno JA, Perez-Carceles MD, Osuna E, Luna A. Preoperative information and informed consent in surgically treated patients. Rev Esp Anestesiol Reanim 1998;45(4): 130–5

    CAS  PubMed  Google Scholar 

  13. Zardawi IM. Fine needle aspiration cytology in a rural setting. Acta Cytol 1998;42(4):899–906

    CAS  PubMed  Google Scholar 

  14. Nasuti JF, Gupta PK, Baloch ZW. Diagnostic value and cost-effectiveness of on-site evaluation of fine-needle aspiration specimens: review of 5,688 cases. Diagn Cytopathol 2002;27(1):1–4

    PubMed  Google Scholar 

  15. Lazda EJ, Kocjan G, Sams VR, Wotherspoon AC, Taylor I. Fine needle aspiration (FNA) cytology of the breast: the influence of unsatisfactory samples on patient management. Cytopathology 1996;7(4):262–7

    Article  CAS  PubMed  Google Scholar 

  16. Lee HC, Ooi PJ, Poh WT, Wong CY. Impact of inadequate fine-needle aspiration cytology on outcome of patients with palpable breast lesions. Aust N Z J Surg 2000;70(9):656–9

    Article  CAS  PubMed  Google Scholar 

  17. MacDonald L, Yazdi HM. Nondiagnostic fine needle aspiration biopsy of the thyroid gland: a diagnostic dilemma. Acta Cytol 1996;40(3):423–8

    CAS  PubMed  Google Scholar 

  18. Robinson IA, Cozens NJ. Does a joint ultrasound guided cytology clinic optimize the cytological evaluation of head and neck masses? Clin Radiol 1999;54(5):312–6

    Article  CAS  PubMed  Google Scholar 

  19. Brown LA, Coghill SB. Fine needle aspiration cytology of the breast: factors affecting sensitivity. Cytopathology 1991;2(2):67–74

    CAS  PubMed  Google Scholar 

  20. Hamill J, Campbell ID, Mayall F, Bartlett AS, Darlington A. Improved breast cytology results with near patient FNA diagnosis. Acta Cytol 2002;46(1): 19–24

    PubMed  Google Scholar 

  21. Kocjan G. Evaluation of the cost effectiveness of establishing a fine needle aspiration cytology clinic in a hospital out-patient department. Cytopathology 1991;2(1):13–8

    CAS  PubMed  Google Scholar 

  22. Boerner S, Sneige N. Specimen adequacy and false-negative diagnosis rate in fine-needle aspirates of palpable breast masses. Cancer 1998;84(6):344–8

    Article  CAS  PubMed  Google Scholar 

  23. Brown LA, Coghill SB. Cost effectiveness of a fine needle aspiration clinic. Cytopathology 1992;3(5):275–80

    CAS  PubMed  Google Scholar 

  24. Dray M, Mayall F, Darlington A. Improved fine needle aspiration (FNA) cytology results with a near patient diagnosis service for breast lesions. Cytopathology 2000; 11(1):32–7

    Article  CAS  PubMed  Google Scholar 

  25. Lieu D. Fine-needle aspiration: technique and smear preparation. Am Fam Physician 1997;55(3):839–46, 853–4

    CAS  PubMed  Google Scholar 

  26. Mayall F, Denford A, Chang B, Darlington A. Improved FNA cytology results with a near patient diagnosis service for non-breast lesions. J Clin Pathol 1998;51(7):541–4

    CAS  PubMed  Google Scholar 

  27. Stanley MW. Cost benefit and outcomes analysis for fine-needle aspiration. Why do we know so little? Clin Lab Med 1999;19(4):773–81

    CAS  PubMed  Google Scholar 

  28. Young NA, Mody DR, Davey DD. Misinterpretation of normal cellular elements in fine-needle aspiration biopsy specimens: observations from the College of American Pathologists Interlaboratory Comparison Program in Non-Gynecologic Cytopathology. Arch Pathol Lab Med 2002;126(6):670–5

    PubMed  Google Scholar 

  29. Knappe M, Louw M, Gregor RT. Ultrasonography-guided fine-needle aspiration for the assessment of cervical metastases. Arch Otolaryngol Head Neck Surg 2000;126(9): 1091–6

    CAS  PubMed  Google Scholar 

  30. Sack MJ, Weber RS, Weinstein GS, Chalian AA, Nisenbaum HL, Yousem DM. Image-guided fine-needle aspiration of the head and neck: five years’ experience. Arch Otolaryngol Head Neck Surg 1998;124(10):1155–61

    CAS  PubMed  Google Scholar 

  31. Liao J, Davey DD, Warren G, Davis J, Moore AR, Samayoa LM. Ultrasound-guided fine-needle aspiration biopsy remains a valid approach in the evaluation of nonpalpable breast lesions. Diagn Cytopathol 2004;30(5):325–31

    Article  PubMed  Google Scholar 

  32. Karstrup S, Balslev E, Juul N, Eskildsen PC, Baumbach L. US-guided fine needle aspiration versus coarse needle biopsy of thyroid nodules. Eur J Ultrasound 2001;13(1):1–5

    Article  CAS  PubMed  Google Scholar 

  33. Selinko VL, Middleton LP, Dempsey PJ. Role of sonography in diagnosing and staging invasive lobular carcinoma. J Clin Ultrasound 2004;32(7):323–32

    Article  PubMed  Google Scholar 

  34. Knudsen DU, Nielsen SM, Hariri J, Christensen J, Kristensen S. Ultrasonographically guided fine-needle aspiration biopsy of intrathoracic tumors. Acta Radiol 1996;37 (3 Pt 1):327–31

    CAS  PubMed  Google Scholar 

  35. Byrne MF, Gerke H, Mitchell RM, Stiffler HL, McGrath K, Branch MS, et al. Yield of endoscopic ultrasound-guided fine-needle aspiration of bile duct lesions. Endoscopy 2004;36(8):715–9

    Article  CAS  PubMed  Google Scholar 

  36. Varadarajulu S, Hoffman BJ, Hawes RH, Eloubeidi MA. EUS-guided FNA of lung masses adjacent to or abutting the esophagus after unrevealing CT-guided biopsy or bronchoscopy. Gastrointest Endosc 2004;60(2):293–7

    Article  PubMed  Google Scholar 

  37. Erickson RA. EUS-guided FNA. Gastrointest Endosc 2004;60(2):267–79

    Article  PubMed  Google Scholar 

  38. Afify AM, al-Khafaji BM, Kim B, Scheiman JM. Endoscopic ultrasound-guided fine needle aspiration of the pancreas. Diagnostic utility and accuracy. Acta Cytol 2003;47(3):341–8

    PubMed  Google Scholar 

  39. Agarwal B, Abu-Hamda E, Molke KL, Correa AM, Ho L. Endoscopic ultrasound-guided fine needle aspiration and multidetector spiral CT in the diagnosis of pancreatic cancer. Am J Gastroenterol 2004;99(5):844–50

    Article  PubMed  Google Scholar 

  40. Chen VK, Eloubeidi MA. Endoscopic ultrasound-guided fine needle aspiration is superior to lymph node echofeatures: a prospective evaluation of mediastinal and peri-intestinal lymphadenopathy. Am J Gastroenterol 2004;99(4):628–33

    Article  PubMed  Google Scholar 

  41. Frossard JL, Amouyal P, Amouyal G, Palazzo L, Amaris J, Soldan M, et al. Performance of endosonography-guided fine needle aspiration and biopsy in the diagnosis of pancreatic cystic lesions. Am J Gastroenterol 2003;98(7):1516–24

    Article  PubMed  Google Scholar 

  42. Jhala NC, Jhala D, Eltoum I, Vickers SM, Wilcox CM, Chhieng DC, et al. Endoscopic ultrasound-guided fine-needle aspiration biopsy: a powerful tool to obtain samples from small lesions. Cancer 2004;102(4):239–46

    Article  PubMed  Google Scholar 

  43. Weynand B, Deprez P. Endoscopic ultrasound guided fine needle aspiration in biliary and pancreatic diseases: pitfalls and performances. Acta Gastroenterol Belg 2004;67(3):294–300

    CAS  PubMed  Google Scholar 

  44. Fabre M. Comment reussir une ponction a l’aiguille fine sous echoendoscopie digestive? Acta Endoscopica 2005;35:65–75

    Google Scholar 

  45. Ylagan LR, Edmundowicz S, Kasal K, Walsh D, Lu DW. Endoscopic ultrasound guided fine-needle aspiration cytology of pancreatic carcinoma: a 3-year experience and review of the literature. Cancer 2002;96(6):362–9

    Article  PubMed  Google Scholar 

  46. Layfield LJ, Bentz JS, Gopez EV. Immediate on-site interpretation of fine-needle aspiration smears: a cost and compensation analysis. Cancer 2001;93(5):319–22

    Article  CAS  PubMed  Google Scholar 

  47. Harewood GC, Wiersema LM, Halling AC, Keeney GL, Salamao DR, Wiersema MJ. Influence of EUS training and pathology interpretation on accuracy of EUS-guided fine needle aspiration of pancreatic masses. Gastrointest Endosc 2002;55(6):669–73

    Article  PubMed  Google Scholar 

  48. Arslan S, Yilmaz A, Bayramgurler B, Uzman O, Nver E, Akkaya E. CT-guided transthoracic fine needle aspiration of pulmonary lesions: accuracy and complications in 294 patients. Med Sci Monit 2002;8(7):CR493–7

    PubMed  Google Scholar 

  49. Austin JH, Cohen MB. Value of having a cytopathologist present during percutaneous fine-needle aspiration biopsy of lung: report of 55 cancer patients and metaanalysis of the literature. AJR Am J Roentgenol 1993;160(1):175–7

    CAS  PubMed  Google Scholar 

  50. Kucuk CU, Yilmaz A, Akkaya E. Computed tomography-guided transthoracic fine-needle aspiration in diagnosis of lung cancer: a comparison of single-pass needle and multiple-pass coaxial needle systems and the value of immediate cytological assessment. Respirology 2004;9(3):392–6

    Article  PubMed  Google Scholar 

  51. Padhani AR, Scott WW, Jr., Cheema M, Kearney D, Erozan YS. The value of immediate cytologic evaluation for needle aspiration lung biopsy. Invest Radiol 1997;32(8):453–8

    Article  CAS  PubMed  Google Scholar 

  52. Hughes JH, Volk EE, Wilbur DC. Pitfalls in salivary gland fine-needle aspiration cytology: lessons from the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology. Arch Pathol Lab Med 2005;129(1):26–31

    PubMed  Google Scholar 

  53. Snead DR, Vryenhoef P, Pinder SE, Evans A, Wilson AR, Blamey RW, et al. Routine audit of breast fine needle aspiration (FNA) cytology specimens and aspirator inadequate rates. Cytopathology 1997;8(4):236–47

    Article  CAS  PubMed  Google Scholar 

  54. Pennes DR, Naylor B, Rebner M. Fine needle aspiration biopsy of the breast. Influence of the number of passes and the sample size on the diagnostic yield. Acta Cytol 1990;34(5):673–6

    CAS  PubMed  Google Scholar 

  55. Joseph L, Edwards JM, Nicholson CM, Pitt MA, Howat AJ. An audit of the accuracy of fine needle aspiration using a liquid-based cytology system in the setting of a rapid access breast clinic. Cytopathology 2002;13(6):343–9

    Article  CAS  PubMed  Google Scholar 

  56. NHS. Breast Screening Programme: Guidelines for Cytology procedures and reporting in breast cancer screening. NHS Publication 1992;22:18

    Google Scholar 

  57. Rubenchik I, Sneige N, Edeiken B, Samuels B, Fornage B. In search of specimen adequacy in fine-needle aspirates of nonpalpable breast lesions. Am J Clin Pathol 1997;108(1):13–8

    CAS  PubMed  Google Scholar 

  58. Coghill SB, Brown LA. Why pathologists should take needle aspiration specimens. Cytopathology 1995;6(1):1–4

    CAS  PubMed  Google Scholar 

  59. Hoda RS. Why pathologists should take needle aspiration specimens. Cytopathology 1995;6(6):419–20

    CAS  PubMed  Google Scholar 

  60. Fessia L, Botta G, Arisio R, Verga M, Aimone V. Fine-needle aspiration of breast lesions: role and accuracy in a review of 7,495 cases. Diagn Cytopathol 1987;3(2):121–5

    CAS  PubMed  Google Scholar 

  61. Howat AJ. Why pathologists should take needle aspiration specimens. Cytopathology 1995;6(6):419

    CAS  PubMed  Google Scholar 

  62. Singh N RD, Berney M, Calaminici MT, Sheaff T, Wells A. Inadequate rates are lower when FNAC samples are taken by cytopathologists. Cytopathology 2003 Dec;14(6):327–31

    Article  CAS  PubMed  Google Scholar 

  63. Padel AF, Coghill SB, Powis SJ. Evidence that the sensitivity is increased and the inadequacy rate decreased when pathologists take aspirates for cytodiagnosis. Cytopathology 1993;4(3):161–5

    CAS  PubMed  Google Scholar 

  64. Kamal MM, Arjune DG, Kulkarni HR. Comparative study of fine needle aspiration and fine needle capillary sampling of thyroid lesions. Acta Cytol 2002;46(1):30–4

    PubMed  Google Scholar 

  65. CM K. Cytopreparatory techniques. In: Bibbo M (ed) Comprehensive Cytopathology 1991;Philadelphia: WB Saunders

    Google Scholar 

  66. Howat AJ, Armstrong GR, Briggs WA, Nicholson CM, Stewart DJ. Fine needle aspiration of palpable breast lumps: a 1-year audit using the Cytospin method. Cytopathology 1992;3(1):17–22

    CAS  PubMed  Google Scholar 

  67. Cytic. Thin Prep Non Gyn FNA. http://www.thinprep.com/lab/lab_thinprep_nongyn_fna.shtml;ThinPrep Processor Operator’s Manual. P/N 85489-002 Rev. G

    Google Scholar 

  68. TriPath Imaging I. http://www.tripathimaging.com/usproducts/surepath.htm CytoRich preservative

    Google Scholar 

  69. Bedard YC, Pollett AF. Breast fine-needle aspiration. A comparison of ThinPrep and conventional smears. Am J Clin Pathol 1999;111(4):523–7

    CAS  PubMed  Google Scholar 

  70. TriPath Imaging I. Prep Stain System Operator’s Manual. (Burlington, NC)

    Google Scholar 

  71. Cytic. System Operator’s Manual. Cytic Corporation, Boxborough, MA, USA 1995

    Google Scholar 

  72. Cattoretti G. Preparation of cytospin from single cell suspension. Lab Protocols 2002:http://icg.cpmc.columbia.edu/cattoretti/Protocol/immunohistoche-mistry/CytospinPreparation.html

    Google Scholar 

  73. Zito FA, Gadaleta CD, Salvatore C, Filotico R, Labriola A, Marzullo A, et al. A modified cell block technique for fine needle aspiration cytology. Acta Cytol 1995;39(1):93–9

    CAS  PubMed  Google Scholar 

  74. Rowe LR, Marshall CJ, Bentz JS. Cell block preparation as an adjunctive diagnostic technique in ThinPrep monolayer preparations: a case report. Diagn Cytopathol 2001;24(2):142–4

    Article  CAS  PubMed  Google Scholar 

  75. Yang GC, Papellas J, Wu HC, Waisman J. Application of Ultrafast Papanicolaou stain to body fluid cytology. Acta Cytol 2001;45(2):180–5

    CAS  PubMed  Google Scholar 

  76. Papanicolaou G. A new procedure for staining vaginal smears. Science 1942;5:432

    Google Scholar 

  77. Street C. Papanicolaou Techniques in Exfoliative Cytology. In: Cawdry EV (ed) Laboratory Technique in Biology and Medicine, 3rd edn, Williams and Wilkins 1952:253

    Google Scholar 

  78. NHS. External Quality Assessment Scheme for the Evaluation of Papanicolaou Staining in Cervical Cytology. NHS CSP Handbook 2004; vesrion 1

    Google Scholar 

  79. Boon M. Routine cytologic staining procedures. In: Weid GL, Bibbo M, Keebler CM, Koss LG, Patten SM, Rosenthal DL (eds) Tutorials of Cytology, International Academy of Cytology, Chicago 1992

    Google Scholar 

  80. ASC CPC. Non Gynaecological Cytology Practice Guidelines. 2004;para III c

    Google Scholar 

  81. Crystal BS, Wang HH, Ducatman BS. Comparison of different preparation techniques for fine needle aspiration specimens. A semiquantitative and statistical analysis. Acta Cytol 1993;37(1):24–8

    CAS  PubMed  Google Scholar 

  82. Yang GC. Ultrafast Papanicolaou stain is not limited to rapid assessments: application to permanent fine-needle aspiration smears. Diagn Cytopathol 1995;13(2): 160–2

    CAS  PubMed  Google Scholar 

  83. Yang GC, Alvarez, II. Ultrafast Papanicolaou stain. An alternative preparation for fine needle aspiration cytology. Acta Cytol 1995;39(1):55–60

    CAS  PubMed  Google Scholar 

  84. Bandlish U, Kapoor K, Shukla S. Efficacy of a modified ultrafast Papanicolaou (UFP) stain for breast aspirates. J Indian Med Assoc 2004;102(6):309, 312, 326

    PubMed  Google Scholar 

  85. Maruta J, Hashimoto H, Yamashita H, Noguchi S. Quick aspiration cytology for thyroid nodules by modified Ultrafast Papanicolaou staining. Diagn Cytopathol 2003;28(1):45–8

    Article  PubMed  Google Scholar 

  86. Zu Y, Gangi MD, Yang GC. Ultrafast Papanicolaou stain and cell-transfer technique enhance cytologic diagnosis of Hodgkin lymphoma. Diagn Cytopathol 2002;27(5):308–11

    Article  PubMed  Google Scholar 

  87. Chhieng DC, Benson E, Eltoum I, Eloubeidi MA, Jhala N, Jhala D, et al. MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration. Cancer 2003;99(6):365–71

    Article  CAS  PubMed  Google Scholar 

  88. Ng WK, Ip P, Choy C, Collins RJ. Cytologic and immunocytochemical findings of anaplastic large cell lymphoma: analysis often fine-needle aspiration specimens over a 9-year period. Cancer 2003;99(1):33–43

    Article  PubMed  Google Scholar 

  89. Dong HY, Harris NL, Preffer FI, Pitman MB. Fine-needle aspiration biopsy in the diagnosis and classification of primary and recurrent lymphoma: a retrospective analysis of the utility of cytomorphology and flow cytometry. Mod Pathol 2001;14(5):472–81

    Article  CAS  PubMed  Google Scholar 

  90. Fiegl M, Haun M, Massoner A, Krugmann J, Muller-Holzner E, Hack R, et al. Combination of cytology, fluorescence in situ hybridization for aneuploidy, and reverse-transcriptase polymerase chain reaction for human mammaglobin/mammaglobin B expression improves diagnosis of malignant effusions. J Clin Oncol 2004;22(3):474–83

    CAS  PubMed  Google Scholar 

  91. Gong JZ, Williams DC, Jr., Liu K, Jones C. Fine-needle aspiration in non-Hodgkin lymphoma: evaluation of cell size by cytomorphology and flow cytometry. Am J Clin Pathol 2002;117(6):880–8

    PubMed  Google Scholar 

  92. Henrique RM, Sousa ME, Godinho MI, Costa I, Barbosa IL, Lopes CA. Immunophenotyping by flow cytometry of fine needle aspirates in the diagnosis of lymphoproliferative disorders: A retrospective study. J Clin Lab Anal 1999;13(5):224–8

    Article  CAS  PubMed  Google Scholar 

  93. Katz RL, Wojcik EM, el-Naggar AK, Ordonez NG, Johnston DA. Proliferation markers in non-Hodgkin’s lymphoma. A comparative study between cytophotometric quantitation of Ki-67 and flow cytometric proliferation index on fine needle aspirates. Anal Quant Cytol Histol 1993;15(3):179–86

    CAS  PubMed  Google Scholar 

  94. Lavarino C, Corletto V, Mezzelani A, Della Torre G, Bartoli C, Riva C, et al. Detection of TP53 mutation, loss of heterozygosity and DNA content in fine-needle aspirates of breast carcinoma. Br J Cancer 1998;77(1):125–30

    CAS  PubMed  Google Scholar 

  95. Salto-Tellez M, Koay ES. Molecular diagnostic cytopathology: definitions, scope and clinical utility. Cytopathology 2004;15(5):252–5

    Article  CAS  PubMed  Google Scholar 

  96. Elzagheid A, Kuopio T, Collan Y. Implementation of DNA cytometric measurements in fine-needle aspiration biopsy diagnostics of breast disease. Cancer 2004;102(6):380–8

    Article  PubMed  Google Scholar 

  97. Howes GP, Stephenson J, Humphreys S. Sensitive and reliable PCR and sequencing used to detect p53 point mutations in fine needle aspirates of the breast. J Clin Pathol 1996;49(7):570–3

    CAS  PubMed  Google Scholar 

  98. Tisserand P, Fouquet C, Marck V, Mallard C, Fabre M, Vielh P, et al. ThinPrep-processed fine-needle samples of breast are effective material for RNA-and DNA-based molecular diagnosis: application to p53 mutation analysis. Cancer 2003;99(4):223–32

    Article  CAS  PubMed  Google Scholar 

  99. Jeffers MD MJ, Farquharson MA, Stewart CJ, Mutch AF. Analysis of clonality in cytologic material using the polymerase chain reaction (PCR). Cytopathology 1997;8(2):114–21

    CAS  PubMed  Google Scholar 

  100. Glanzer JG, Eberwine JH. Expression profiling of small cellular samples in cancer: less is more. Br J Cancer 2004;90(6):1111–4

    Article  CAS  PubMed  Google Scholar 

  101. Symmans WF, Ayers M, Clark EA, Stec J, Hess KR, Sneige N, et al. Total RNA yield and microarray gene expression profiles from fine-needle aspiration biopsy and core-needle biopsy samples of breast carcinoma. Cancer 2003;97(12):2960–71

    Article  CAS  PubMed  Google Scholar 

  102. Pusztai L, Ayers M, Stec J, Clark E, Hess K, Stivers D, et al. Gene expression profiles obtained from fine-needle aspirations of breast cancer reliably identify routine prognostic markers and reveal large-scale molecular differences between estrogen-negative and estrogen-positive tumors. Clin Cancer Res 2003;9(7):2406–15

    CAS  PubMed  Google Scholar 

  103. Kainuma K, Katsuno S, Hashimoto S, Suzuki N, Oguchi T, Asamura K, et al. Identification of differentially expressed genes in salivary gland tumors with cDNA microarray. Auris Nasus Larynx 2004;31(3):261–8

    Article  PubMed  Google Scholar 

  104. Assersohn L, Gangi L, Zhao Y, Dowsett M, Simon R, Powles TJ, et al. The feasibility of using fine needle aspiration from primary breast cancers for cDNA microarray analyses. Clin Cancer Res 2002;8(3):794–801

    CAS  PubMed  Google Scholar 

  105. Ayers M, Symmans WF, Stec J, Damokosh AI, Clark E, Hess K, et al. Gene expression profiles predict complete pathologic response to neoadjuvant paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide chemotherapy in breast cancer. J Clin Oncol 2004;22(12):2284–93

    Article  CAS  PubMed  Google Scholar 

  106. Blancato J, Singh B, Liu A, Liao DJ, Dickson RB. Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses. Br J Cancer 2004;90(8):1612–9

    Article  CAS  PubMed  Google Scholar 

  107. Cleator S, Ashworth A. Molecular profiling of breast cancer: clinical implications. Br J Cancer 2004;90(6):1120–4

    Article  CAS  PubMed  Google Scholar 

  108. Dunmire V, Wu C, Symmans WF, Zhang W. Increased yield of total RNA from fine-needle aspirates for use in expression microarray analysis. Biotechniques 2002;33(4):890–2, 894, 896

    CAS  PubMed  Google Scholar 

  109. Garber K. Genomic medicine. Gene expression tests foretell breast cancer’s future. Science 2004;303(5665):1754–5

    Article  PubMed  Google Scholar 

  110. Glinsky GV, Higashiyama T, Glinskii AB. Classification of human breast cancer using gene expression profiling as a component of the survival predictor algorithm. Clin Cancer Res 2004;10(7):2272–83

    CAS  PubMed  Google Scholar 

  111. Gong Y, Symmans WF, Krishnamurthy S, Patel S, Sneige N. Optimal fixation conditions for immunocytochemical analysis of estrogen receptor in cytologic specimens of breast carcinoma. Cancer 2004;102(1):34–40

    Article  CAS  PubMed  Google Scholar 

  112. Hampton T. Breast cancer gene chip study under way: can new technology help predict treatment success? JAMA 2004;291(24):2927–30

    CAS  PubMed  Google Scholar 

  113. Hao X, Sun B, Hu L, Lahdesmaki H, Dunmire V, Feng Y, et al. Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis. Cancer 2004;100(6):1110–22

    Article  CAS  PubMed  Google Scholar 

  114. Jeffrey SS, Fero MJ, Borresen-Dale AL, Botstein D. Expression array technology in the diagnosis and treatment of breast cancer. Mol Interv 2002;2(2):101–9

    Article  CAS  PubMed  Google Scholar 

  115. Miller DV, Leontovich AA, Lingle WL, Suman VJ, Mertens ML, Lillie J, et al. Utilizing Nottingham Prognostic Index in microarray gene expression profiling of breast carcinomas. Mod Pathol 2004;17(7):756–64

    Article  CAS  PubMed  Google Scholar 

  116. Nagahata T, Onda M, Emi M, Nagai H, Tsumagari K, Fujimoto T, et al. Expression profiling to predict postoperative prognosis for estrogen receptor-negative breast cancers by analysis of 25,344 genes on a cDNA microarray. Cancer Sci 2004;95(3):218–25

    Article  CAS  PubMed  Google Scholar 

  117. Roh MS, Hong SH, Jeong JS, Kwon HC, Kim MC, Cho SH, et al. Gene expression profiling of breast cancers with emphasis of beta-catenin regulation. J Korean Med Sci 2004;19(2):275–82

    CAS  PubMed  Google Scholar 

  118. Ross JS, Linette GP, Stec J, Clark E, Ayers M, Leschly N, et al. Breast cancer biomarkers and molecular medicine: part II. Expert Rev Mol Diagn 2004;4(2): 169–88

    Article  CAS  PubMed  Google Scholar 

  119. Wajapeyee N, Somasundaram K. Pharmacogenomics in breast cancer: current trends and future directions. Curr Opin Mol Ther 2004;6(3):296–301

    CAS  PubMed  Google Scholar 

  120. Weigelt B, Verduijn P, Bosma AJ, Rutgers EJ, Peterse HL, an’t Veer LJ. Detection of metastases in sentinel lymph nodes of breast cancer patients by multiple mRNA markers. Br J Cancer 2004;90(8):1531–7

    Article  CAS  PubMed  Google Scholar 

  121. Wu W, Chaudhuri S, Brickley DR, Pang D, Karrison T, Conzen SD. Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells. Cancer Res 2004;64(5):1757–64

    Article  CAS  PubMed  Google Scholar 

  122. Yu K, Lee CH, Tan PH, Hong GS, Wee SB, Wong CY, et al. A molecular signature of the Nottingham prognostic index in breast cancer. Cancer Res 2004;64(9):2962–8

    Article  CAS  PubMed  Google Scholar 

  123. Zhang DH, Salto-Tellez M, Chiu LL, Shen L, Koay ES. Tissue microarray study for classification of breast tumours. Ann Acad Med Singapore 2003;32(5 Suppl):S75–6

    CAS  PubMed  Google Scholar 

  124. Zhang D, Salto-Tellez M, Do E, Putti TC, Koay ES. Evaluation of HER-2/neu oncogene status in breast tumors on tissue microarrays. Hum Pathol 2003;34(4):362–8

    Article  CAS  PubMed  Google Scholar 

  125. Zhang D, Salto-Tellez M, Putti TC, Do E, Koay ES. Reliability of tissue microarrays in detecting protein expression and gene amplification in breast cancer. Mod Pathol 2003;16(1):79–84

    Article  PubMed  Google Scholar 

  126. Zhao H, Langerod A, Ji Y, Nowels KW, Nesland JM, Tibshirani R, et al. Different gene expression patterns in invasive lobular and ductal carcinomas of the breast. Mol Biol Cell 2004;15(6):2523–36

    Article  CAS  PubMed  Google Scholar 

  127. Davis RE, Staudt LM. Molecular diagnosis of lymphoid malignancies by gene expression profiling. Curr Opin Hematol 2002;9(4):333–8

    Article  PubMed  Google Scholar 

  128. Borovecki A, Kardum-Skelin I, Sustercic D, Hitrec V, Lasan R, Jaksic B. Chromosomal abnormalities and DNA image cytometry of haematological neoplasms in fine needle aspirates of lymph nodes. Cytopathology 2003;14(6):320–6

    Article  CAS  PubMed  Google Scholar 

  129. Safley AM, Buckley PJ, Creager AJ, Dash RC, Dodd LG, Goodman BK, et al. The value of fluorescence in situ hybridization and polymerase chain reaction in the diagnosis of B-cell non-Hodgkin lymphoma by fine-needle aspiration. Arch Pathol Lab Med 2004;128(12): 1395–403

    CAS  PubMed  Google Scholar 

  130. Bentz JS, Rowe LR, Anderson SR, Gupta PK, McGrath CM. Rapid detection of the t(11;14) translocation in mantle cell lymphoma by interphase fluorescence in situ hybridization on archival cytopathologic material. Cancer 2004;102(2):124–31

    Article  CAS  PubMed  Google Scholar 

  131. Salto-Tellez M, Zhang D, Chiu LL, Wang SC, Nilsson B, Koay ES. Immunocytochemistry versus molecular fingerprinting of metastases. Cytopathology 2003;14(4):186–90

    Article  CAS  PubMed  Google Scholar 

  132. Sneige N. Utility of cytologic specimens in the evaluation of prognostic and predictive factors of breast cancer: current issues and future directions. Diagn Cytopathol 2004;30(3):158–65

    Article  PubMed  Google Scholar 

  133. Nizzoli R, Bozzetti C, Crafa P, Naldi N, Guazzi A, Di Blasio B, et al. Immunocytochemical evaluation of HER-2/neu on fine-needle aspirates from primary breast carcinomas. Diagn Cytopathol 2003;28(3): 142–6

    Article  PubMed  Google Scholar 

  134. Pellise M, Castells A, Gines A, Agrelo R, Sole M, Castellvi-Bel S, et al. Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonography-guided fine-needle aspiration biopsy. Clin Cancer Res 2004;10(13):4444–9

    CAS  PubMed  Google Scholar 

  135. Bruijnesteijn Van Coppenraet ES, Lindeboom JA, Prins JM, Peeters MF, Claas EC, Kuijper EJ. Real-time PCR assay using fine-needle aspirates and tissue biopsy specimens for rapid diagnosis of mycobacterial lymphadenitis in children. J Clin Microbiol 2004;42(6):2644–50

    Article  CAS  PubMed  Google Scholar 

  136. Avidor B, Varon M, Marmor S, Lifschitz-Mercer B, Kletter Y, Ephros M, et al. DNA amplification for the diagnosis of cat-scratch disease in small-quantity clinical specimens. Am J Clin Pathol 2001;115(6):900–9

    CAS  PubMed  Google Scholar 

  137. www.doh.gov.uk/chcguid1.htm

    Google Scholar 

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© 2006 Springer-Verlag Berlin Heidelberg

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(2006). FNAC Technique and Slide Preparation. In: Fine Needle Aspiration Cytology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-31412-1_2

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  • DOI: https://doi.org/10.1007/3-540-31412-1_2

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