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Modeling of the Effects of Growth on the Local Environment

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Solid-State Fermentation Bioreactors

17.5 Conclusions

Chapters 14 to 17 have given an overview of the experimental and mathematical steps in the development of the kinetic sub-model of an SSF bioreactor model. Chapters 18 to 20 will address basic principles related to the balance/transport sub-model.

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Further Reading

  • Sato K, Nagatani M, Nakamura KI, Sato S (1983) Growth estimation of Candida lipolytica from oxygen uptake in a solid state culture with forced aeration. J Ferment Technol 61:623–629

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  • Cooney CL, Wang DIC, Mateles RI (1968) Measurement of heat evolution and correlation with oxygen consumption during microbial growth. Biotechnol Bioeng 11:269–281

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  • Rajagopalan S, Rockstraw DA, Munson-McGee SH (1997) Modeling substrate particle degradation by Bacillus coagulans biofilm. Bioresource Technol 61:175–183

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  • Mitchell DA, Berovic M, Krieger N (2000) Biochemical engineering aspects of solid state bioprocessing. Adv Biochem Eng/Biotech 68:61–138

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  • Mitchell DA, von Meien OF, Krieger N, Dalsenter FDH (2004) A review of recent developments in modeling of microbial growth kinetics and intraparticle phenomena in solid-state fermentation. Biochem Eng J 17:15–26

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  • Nagel FJI, Tramper J, Bakker MSN, Rinzema A (2001b) Model for on-line moisture-content control during solid-state fermentation. Biotechnol Bioeng 72:231–243

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Mitchell, D.A., Krieger, N. (2006). Modeling of the Effects of Growth on the Local Environment. In: Mitchell, D.A., Berovič, M., Krieger, N. (eds) Solid-State Fermentation Bioreactors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-31286-2_17

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