14.1 Conclusion
There is more evidence that matrix destruction in inflammatory cardiomyopathy is a secondary event to virus infection caused by a cascade of processes induced by the inflammatory response to virus infection and loss of myocytes than matrix destruction is a specific process caused by virus proteases.
It is, however, possible that both processes, a direct virus effect and an indirect effect from virus infection, act in cooperation. Future treatment with specific antiviral therapy may show which mechanism is the dominating factor in inflammatory cardiomyopathy causing matrix destruction.
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Waagstein, F. (2006). Invited for Debate: Is There a Virus-Specific Matrix Destruction in the Course of Disease in Dilated Cardiomyopathy?. In: Schultheiss, H.P., Kapp, J.F., Grötzbach, G. (eds) Chronic Viral and Inflammatory Cardiomyopathy. Ernst Schering Research Foundation Workshop, vol 55. Springer, Berlin, Heidelberg . https://doi.org/10.1007/3-540-30822-9_14
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DOI: https://doi.org/10.1007/3-540-30822-9_14
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