Nomenclature
EC number
1.14.99.19
Systematic name
O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,hydrogen-donor:oxygen oxidoreductase
Recommended name
plasmanylethanolamine desaturase
Synonyms
1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase
alkylacylglycero-phosphorylethanolamine dehydrogenase
alkylacylglycerophosphoethanolamine desaturase
dehydrogenase, alkyl-acylglycerophosphorylethanolamine
desaturase, alkylacylglycerophosphorylethanolamine
plasmanyl Δ1,-desaturase <1> [7]
plasmanylethanolamine Δ1-desaturase <1, 2, 3, 4> [8]
CAS registry number
39391-13-4
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References
Paltauf, F.; Holasek, A.: Enzymatic synthesis of plasmalogens. Characterization of the 1-O-alkyl-2-acyl-8n-glycero-3-phosphorylethanolamine desaturase from mucosa of hamster small intestine. J. Biol. Chem., 248, 1609–1615 (1973)
Wykle, R.L.; Blank, M.L.; Malone, B.; Snyder, F.: Evidence for a mixed function oxidase in the biosynthesis of ethanolamine plasmalogens from 1-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine. J. Biol. Chem., 247, 5442–5447 (1972)
Lee, F.C.; Wykle, R.L.; Blank, M.L.; Snyder, F.: Dietary control of stearyl CoA and alkylacylglycerophosphorylethanolamine desaturases in tumor. Biochem. Biophys. Res. Commun., 55, 574–579 (1973)
Wykle, R.L.; Schremmer, J.M.: Biosynthesis of plasmalogens by the microsomal fraction of Fischer R-3259 sarcoma. Influence of specific 2-acyl chains on the desaturation of 1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine. Biochemistry, 18, 3512–3517 (1979)
Weber, N.; Richter, J.: Formation of ether lipids and wax esters in mammalian cells. Specificity of enzymes with regard to carbon chains of substrates. Biochim. Biophys. Acta, 711, 197–207 (1982)
Baumann, W.J.; Madson, T.H.; Chang, N.; Bandi, P.C.; Schmidt, H.H.O.: On the substrate specificity of enol ether formation in rat brain. Metabolism of O-alkyl ethanediol phosphorylethanolamine. Biochem. Biophys. Res. Commun., 66, 717–724 (1975)
Das, A.K.; Hajra, A.K.: A novel chemical synthesis of 1-O-hexadecyl-rac-[2-3H]glycero-3-phosphorylethanolamine and a simple assay for plasmanyl desaturase. J. Lipid Res., 37, 2706–2714 (1996)
Blank, M.L.; Snyder, F.: Plasmanylethanolamine δ1-desaturase. Methods Enzymol., 209, 390–396 (1992)
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(2006). Plasmanylethanolamine desaturase. In: Schomburg, D., Schomburg, I. (eds) Springer Handbook of Enzymes. Springer Handbook of Enzymes, vol 27. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-30439-8_46
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DOI: https://doi.org/10.1007/3-540-30439-8_46
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