Results and Conclusion
The operative mortality is about 1–2%. For those undergoing clearance of coeliac and superior mesenteric arteries, diarrhoea has been a particular problem. At the present time age and stage are the main determinants of survival — age under 1 year and low stage are associated with an improved outcome. For those with localized tumours survival is in the region of 90–100%. The role of surgery in managing those with locally advanced or metastatic disease is unclear. However, recent evidence suggests that complete excision confers a survival advantage for those with stage 3 disease, although it is not clear that complete excision improves survival in those with metastatic disease. This remains at about 30%.
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Selected Bibliography
Brodeur GM, Pritchard J, Berthold F (1993) Revisions of the international criteria for neuroblastoma diagnosis, staging and response to treatment. J Clin Oncol 11:1466–1477
Carachi R (2002) Perspectives on neuroblastoma. Pediatr Surg Int 18:299–305
Evans AE, Silber JH, Shpilsky A (1996) Successful management of low-stage neuroblastoma without adjuvant therapies: a comparison of two decades, 1972 through 1981 and 1982 through 1992, in a single institution. J Clin Oncol 14:2504–2510
Shorter NA, Davidoff Am, Evans AE (1995) The role of surgery in the management of stage IV neuroblastoma: a single institution study. Med Pediatr Oncol 24:287–291
Weinstein JL, Katzentein HM, Cohn SL (2003) Advances in the diagnosis and treatment of neuroblastoma. Oncologist 8:278–292
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Kiely, E. (2006). Neuroblastoma. In: Puri, P., Höllwarth, M.E. (eds) Pediatric Surgery. Springer Surgery Atlas Series. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-30258-1_42
Download citation
DOI: https://doi.org/10.1007/3-540-30258-1_42
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-40738-6
Online ISBN: 978-3-540-30258-2
eBook Packages: MedicineMedicine (R0)