Skip to main content

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

  • 2079 Accesses

5.5 Conclusion

In imaging of the hip and bony pelvis the nuclear medicine bone scintigraph can be of enormous value. It is a highly sensitive technique for determining abnormal bone. When normal patterns of physiological uptake and symmetry are taken into account it is a powerful tool for identifying altered skeletal metabolism in a wide range of disorders. Many conditions also have a well-known pattern of uptake which, if seen, aid in diagnosis. Other tests such as for infection can be used alone or together with bone scintigraphy to define with high sensitivity and specificity infection in soft tissue, bone and joint replacements. PET scanning is a relatively new technique which in the hip and pelvis can define metastatic disease and shows enormous potential in imaging infection.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Blau M, Nagler W, Bender MA (1962) A new isotope for bone scanning. J Nucl Med 3:332–334

    PubMed  CAS  Google Scholar 

  • Brown CV, Miller JH (1994) Extraskeletal extravasation of MDP in soft tissue seconadry to methotrexate infiltration. Clin Nucl Med 19:357–358

    PubMed  CAS  Google Scholar 

  • Cawley KA, Dvorak AD, Wilmot AD (1983) Normal anatomical variant: scintigraphy of the ischiopubic synchondrosis. J Nucl Med 24:14–16

    PubMed  CAS  Google Scholar 

  • Cheran SK, Herndon JE, Patz EF Jr (2004) Comparison of whole body FDG-PET to bone scan for bone metastases in patients with a new diagnosis of lung cancer. Lung Cancer 44:317–325

    Article  PubMed  Google Scholar 

  • Chew FS, Hudson TM, Enneking WF (1981) Radionuclide imaging of soft tissue neoplasms. Semin Nucl Med 11:277–288

    Google Scholar 

  • Citrin DL, Bessent RG, Greig WR (1977) A comparison of the sensitivity and accuracy of the 99m-Tc-phosphate bone scan and skeletal radiography in the diagnosis of bone metastases. Clin Radiol 28:107–117

    PubMed  CAS  Google Scholar 

  • Collier BD, Carrera GF, Johnson RP et al (1985) Detection of femoral head avascular necrosis in adults by SPECT. J Nucl Med 26:979–987

    PubMed  CAS  Google Scholar 

  • Constable AR, Cranage RW (1981) Recognition of the superscan in prostatic bone scintigraphy. Br J Radiol 54:122–125

    PubMed  CAS  Google Scholar 

  • Cook GJ, Houston S, Reubens R et al (1998) Detection of bone metastases in breast cancer by 18FDG-PET: differing metabolic activity in osteoblastic and osteolytic lesions. J Clin Oncol 16:3375–3379

    PubMed  CAS  Google Scholar 

  • Davis MC, Turner DA, Charters JR et al (1984) Quantitative sacroiliac scintigraphy: the effect of method of selection of the region of interest. Clin Nucl Med 9:334–340

    PubMed  CAS  Google Scholar 

  • Deutsch AI, Mink JH, Waxman AD (1989) Occult fractures of the proximal femur: MR imaging. Radiology 170:113–116

    PubMed  CAS  Google Scholar 

  • Fogelman I (1980) Skeletal uptake of diphosphomate: a review. Eur J Nucl Med 3:224–225

    Google Scholar 

  • Fogelman I, Carr DA (1980) A comparison of bone scanning and radiology in the assessment of patients with symptomatic Paget’s disease. Eur J Nucl Med 5:417–421

    PubMed  CAS  Google Scholar 

  • Hain SF, Cooper RA, Aroney RS et al (1999) Soft-tissue uptake of colonic metastases Clin Nucl Med 24:358–359

    Article  PubMed  CAS  Google Scholar 

  • Handmaker H, Leonard R (1976) The bone scan in inflammatory osseous disease. Semin Nucl Med 6:95

    PubMed  CAS  Google Scholar 

  • Hanly JG, Mitchell MJ, Barnes DC et al (1994) Early recognition of sacroilitis by magnetic resonance imaging and single photon emission computed tomography. J Rheumatol 21:2088–2095

    PubMed  CAS  Google Scholar 

  • Harris WH, Barrack RL (1993) Contemporary algorithms for the evaluation of the painful total hip prosthesis. Orthopaed Rev 22:531–539

    CAS  Google Scholar 

  • Janssen S, Piers DA, Rijswick MH et al (1990) Soft tissue uptake of 99m Tc-disphonate and Tc-99m pyrophosphate in amy-loidosis. Eur J Nucl Med 16:663–670

    Article  PubMed  CAS  Google Scholar 

  • Kujala UM, Orava S, Karpakka J et al (1997) Ischial tuberosity apophysitis and avulsion among athletes. Int J Sports Med 18:149–155

    PubMed  CAS  Google Scholar 

  • Lentle BC, Russell As, Percy JS et al (1977) The scintigraphic investigation of sacroiliac disease. J Nucl Med 18:529–533

    PubMed  CAS  Google Scholar 

  • Martin P (1979) The appearance of bone scans following fractures, including immediate and long-term studies. J Nucl Med 20:1227–1231

    Google Scholar 

  • Miles KA, Harper WH, Finlay DBL et al (1992) Scintigraphic abnormalities in patients woth painful hip replacements treated conservatively. Br J Radiol 65:491–494

    PubMed  CAS  Google Scholar 

  • Namey TC, McIntyre J, Buse M et al (1977) Nucleographic studies of axial spondarthritides. I. Quantitative sacro-iliac scintigraphy in early HLA-B27-associated sacroilitis. Arthritis Rheum 20:1058

    PubMed  CAS  Google Scholar 

  • Orzel JA, Rudd TG, Nelp WB (1984) Heterotopic bone formation(myositis ossificans) and lower extremity swelling mimicking deep vein thrombosis. J Nucl Med 25:1105–1107

    PubMed  CAS  Google Scholar 

  • Oswald SG, van Nostrand D, Savory CG et al (1989) Three phase bone and indium white cell scintigraphy following porous coated hip arthroplasty: a prospective study of the prosthetic hip. J Nucl Med 30:1321–1331

    PubMed  CAS  Google Scholar 

  • Pistenma DA, McDougall IR, Kriss JP (1975) Screening for bone metastases: are only scans necessary? JAMA 231:46–50

    Google Scholar 

  • Rossleigh MA, Lovergrove FTA, Reynolds PM et al (1982) Serial bone scans in the assessment of response to therapy in advanced breast carcinoma. Clin Nucl Med 7:397–402

    PubMed  CAS  Google Scholar 

  • Rossleigh MA, Lovergrove FTA, Reynolds PM et al (1984) The assessment of response to therapy of bone metastases in breast carcinoma. Aust NZ J Med 14:19–22

    CAS  Google Scholar 

  • Russell AS, Lentle BD, Percy JS (1975) Investigations of sacroiliac joints: comparative evaluation of radiological and radionuclide techniques. J Rheumatol 2:45–51

    PubMed  CAS  Google Scholar 

  • Ryan PJ, Gibson T, Fogelman I (1992) Bone scintigraphy following pamidronate therapy for Paget’s disease. J Nucl Med 33:1589–1593

    PubMed  CAS  Google Scholar 

  • Sanz G, Robles JE, Gimenez M et al (1999) Positron emission tomography with 18fluorine-labelled deoxyglucose: utility in localised and advanced prostate cancer. BJU Int 84:1028–1031

    Article  PubMed  CAS  Google Scholar 

  • Seabold JE, Nepola JV, Marsh JL et al (1991) Post-operative bone marrow alterations: potential pitfalls in the diagnosis of osteomyelitis with In 111 labelled leucocyte scintigraphy. Radiology 180:741–747

    PubMed  CAS  Google Scholar 

  • Schirrmeister H, Guhlmann A, Kotzerke J et al (1999) Early detection and accurate description of extent of metastatic disease in breast cancer with flouride ion and positron emission tomography. J Clin Oncol 17:2381–2389

    PubMed  CAS  Google Scholar 

  • Shirazi PH, Ryan WG, Fordham EW (1974) Bone scanning in evaluation of Paget’s disease of the bone. CRC Crit Rev Clin Radiol Nucl Med 5:523–528

    PubMed  CAS  Google Scholar 

  • Shreve PD, Grossman HB, Gross MD et al (1996) Metastatic prostate cancer: initial findings with 2-deoxy-2-[f-18]fluoro-D-glucose. Radiology 199:751–756

    PubMed  CAS  Google Scholar 

  • Tofe AJ, Francis MA, Harvey WJ (1975) Correlation of neoplasms and incidence and localisation of skeletal metastases: an analysis of 1355 diphosphonate bone scans. J Nucl Med 16:986

    PubMed  CAS  Google Scholar 

  • Truit CL, Hartshorne MF, Peters VJ (1998) Subcutaneous ossification of the legs examined with SPECT. Clin Nucl Med 13:423–425

    Google Scholar 

  • Utz G, Lull RJ, Galvin EG (1986) Asymptomatic total hip prosthesis: natural history determined using tc-99m MDP bone scans. Radiology 16:509–512

    Google Scholar 

  • Yeh SD, Imbriaco M, Larson SM et al (1996) Detection of bony metastases of androgen dependent prostate cancer by FDG-PET. Nucl Med Biol 23:693–697

    Article  PubMed  CAS  Google Scholar 

  • Zhuang H, Duarte PS, Pourdehand M et al (2001) The promising role of 18F-FDG PET in detecting infected lower limb prosthesis implants. J Nucl Med 42:44–48

    PubMed  CAS  Google Scholar 

  • Zuckier LS, Patle KA, Wexler JP et al (1990) The hot clot sign: a new finding in deep venous thrombosis on bone scintigraphy. Clin Nucl Med 15:790–793

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Hain, S.F., Fogelman, I. (2006). Nuclear Medicine. In: Davies, A.M., Johnson, K.J., Whitehouse, R.W. (eds) Imaging of the Hip & Bony Pelvis. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-30000-7_5

Download citation

  • DOI: https://doi.org/10.1007/3-540-30000-7_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-20640-8

  • Online ISBN: 978-3-540-30000-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics