Image-Guided/Adaptive Radiotherapy

Part of the Medical Radiology book series (MEDRAD)

25.8 Summary

Adaptive radiotherapy system is designed to systematically manage treatment feedback, planning, and adjustment in response to temporal variations occurring during the radiotherapy course. A temporal variation process, as well as its subprocess, can be classified as a stationary random process or a nonstationary random process. Image feedback is normally designed based on this classification, and the imaging mode can be selected as radiographic imaging, fluoroscopic imaging, and/or 3D/4D CT imaging, with regard to the feature and frequency of a patient anatomical variation, such as rigid body motion and/ or organ deformation induced by treatment setup,organ filling, patient respiration, and/or dose response. Parameters of a temporal variation process, as well as treatment dose in organs of interest, can be estimated using image observations. The estimations are then used to select the planning/adjustment parameters and the schedules of imaging, delivery, and planning/adjustment. Based on the selected parameters and schedules, 4D adaptive planning/adjustment are performed accordingly.

Adaptive radiotherapy represents a new standard of radiotherapy, where a “pre-designed adaptive treatment strategy” a priori treatment delivery will replace the “pre-designed treatment plan” by considering the efficiency, optima, and also clinical practice and cost.


Dose Distribution Radiat Oncol Biol Phys Organ Motion Stationary Random Process Patient Setup 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • Di Yan
    • 1
  1. 1.Clinical Physics Section, Department of Radiation OncologyWilliam Beaumont HospitalRoyal OakUSA

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