Skip to main content
SpringerLink
Log in

Doppler Velocimetry of the Uteroplacental Circulation During Early Pregnancy

  • Chapter
Doppler Ultrasound in Obstetrics and Gynecology

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 269.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Browns I, Robertson WB, Dixon HG (1967) The physiological response of the vessels of the placental bed to normal pregnancy. J Pathol Bacteriol 93:567–579

    Google Scholar 

  2. Pijneborg R, Bland JM, Robertson WB et al (1983) Uteroplacental arterial changes related to interstitial trophoblast migration in early human pregnancy. Placenta 4:397–413

    Google Scholar 

  3. Pijneborg R, Dixon G, Robertson WB et al (1980) Trophoblastic invasion of human decidua from 8–18 weeks of pregnancy. Placenta 1:3–19

    Google Scholar 

  4. Matijevic R, Meekins JW, Walkinshaw SA, Neilson JP, MacFadyen IR (1995) Spiral artery blood flow in the central and peripheral areas of the placental bed in the second trimester. Obstet Gynecol 86:289–292

    Article  PubMed  CAS  Google Scholar 

  5. Ramsey EM (1981) The story of spiral arteries. J Reprod Med 26:393

    PubMed  CAS  Google Scholar 

  6. Reynolds SRM (1965) Physiology of the uterus, 2nd edn. Hafner, New York, p 329

    Google Scholar 

  7. Bieniarz J, Yoshida T, Romero-Salinas G et al (1969) Aortocaval compression by the uterus in late human pregnancy. IV Circulatory homeostasis by preferential perfusion of the placenta. Am J Obstet Gynecol 1034: 10–31

    Google Scholar 

  8. Pinjeborg R, Robertson WB, Brosens I et al (1981) Trophoblast invasion and the establishment of haemochorial placentation in man and laboratory animals. Placenta 2:71–92

    Google Scholar 

  9. Brown JCM, Veall N (1953) The maternal placental blood flow in normotensive and hypertensive women. J Obstet Gynaecol Br Emp 60:141–147

    Google Scholar 

  10. Dixon HG, Browne JCM, Davey D (1963) Choriodecidual and myometrial blood flow. Lancet 1:369–373

    Google Scholar 

  11. Maini CL, Rosati P, Galli G et al (1985) Noninvasive radioisotopic evaluation of placental blood flow. Gynecol Obstet Invest 19:196–206

    PubMed  CAS  Google Scholar 

  12. Trudinger BJ, Giles WB, Cook CM (1985) Uteroplacental blood flow velocity-time waveforms in normal and complicated pregnancy. Br J Obstet Gynaecol 92:39–45

    PubMed  CAS  Google Scholar 

  13. Schulman H, Fleischer A, Farmakides G et al (1986) Development of uterine artery compliance in pregnancy as detected by Doppler ultrasound. Am J Obstet Gynecol 155:1031–1036

    PubMed  CAS  Google Scholar 

  14. Thaler I, Manor D, Itskovitz J et al (1990) Changes in uterine blood flow during human pregnancy. Am J Obstet Gynecol 162:121–125

    PubMed  CAS  Google Scholar 

  15. Brosens I, Robertson WB, Dixon HG (1972) The role of the spiral arteries in the pathogenesis of preeclampsia. Obstet Gynecol Annu 1:177

    PubMed  CAS  Google Scholar 

  16. Khong TY, De Wolf F, Robertson WB et al (1986) Inadequate maternal vascular response to placentation in pregnancies complicated by pre-eclampsia and by small-for-gestational age infants. Br J Obstet Gynaecol 93: 1049–1059

    PubMed  CAS  Google Scholar 

  17. Robertson WB (1976) Uteroplacental vasculature. J Clin Pathol 29[Suppl 10]:9–17

    Google Scholar 

  18. Khong TY, Robertson WB (1992) Spiral artery disease. In: Coulam CB, Faulk WP, McIntyre JA (eds) Immunologic obstetrics. Norton, New York

    Google Scholar 

  19. Stirrat GM (1987) The immunology of hypertension in pregnancy. In: Sharp F, Symonds EM (eds) Hypertension in pregnancy. Perinatology Press, Ithaca, NY, p 249

    Google Scholar 

  20. Khong TY, Sawyer H, Heryet AR (1992) An immunohistologic study of endothelialization of uteroplacental vessels in human pregnancy: evidence that endothelium is focally disrupted by trophoblast in preeclampsia. Am J Obstet Gynecol 167:751–756

    PubMed  CAS  Google Scholar 

  21. Sibai BM (1990) Preeclampsia-eclampsia. Curr Probl Obstet Gynecol Infertil 13:6

    Google Scholar 

  22. DeWolf F, Robertson WB, Brosens I (1975) The ultrastructure of acute atherosis in hypertensive pregnancy. Am J Obstet Gynecol 123:164–174

    CAS  Google Scholar 

  23. Lunell NO, Nylund L, Lewander R et al (1982) Uteroplacental blood flow in preeclampsia: measurements with indium-113 and a computer-linked gamma camera. Clin Exp Hypertens 11:105–117

    Google Scholar 

  24. Campbell S, Griffin DR, Pearce JMF et al (1983) New Doppler technique for assessing uteroplacental blood flow. Lancet 1:675–677

    PubMed  CAS  Google Scholar 

  25. Fleischer A, Schulman H, Farmakides G et al (1986) Uterine artery Doppler velocimetry in pregnant women with hypertension. Am J Obstet Gynecol 154:806–813

    PubMed  CAS  Google Scholar 

  26. Campbell S, Pearce JMF Hackett G et al (1986) Qualitative assessment of uteroplacental blood flow: early screening test for high risk pregnancies. Obstet Gynecol 68:649–653

    PubMed  CAS  Google Scholar 

  27. Arduini D, Rizzo G, Romanini C et al (1987) Uteroplacental blood flow velocity waveforms as predictors of pregnancy-induced hypertension. Eur J Obstet Gynecol Reprod Biol 26:335–341

    Article  PubMed  CAS  Google Scholar 

  28. Voigt J, Becker V (1992) Uteroplacental insufficiency: comparison of uteroplacental blood flow velocimetry and histomorphology of placental bed. J Matern Fetal Invest 2:251–255

    Google Scholar 

  29. Aardema MW, Oosterhof H, Timmer A, Van Rooy I, Aarnoudse JG (2001) Uterine artery Doppler flow and uteroplacental vascular pathology in normal pregnancies and pregnancies complicated by preeclampsia and small for gestational age fetuses. Placenta 22:405–411

    Article  PubMed  CAS  Google Scholar 

  30. Lin S, Shimuzu I, Suehara N, Nakayama M, Aono T (1995) Uterine artery Doppler velocimetry in relation to trophoblast migration into the myometrium of the placental bed. Obstet Gynecol 85:760–765

    Article  PubMed  CAS  Google Scholar 

  31. Ness RB, Roberts JM (1996) Heterogeneous causes constituting the single syndrome of preeclampsia; a hypothesis and its implications. Am J Obstet Gynecol 175:1365–1370

    Article  PubMed  CAS  Google Scholar 

  32. Walters WAW, Lim YL (1975) Blood volume and haemodynamics in pregnancy. Clin Obstet Gynecol 2: 301–320

    Google Scholar 

  33. Christianson RE (1976) Studies of blood pressure during pregnancy. I. Influence of parity and age. Am J Obstet Gynecol 125:509–513

    PubMed  CAS  Google Scholar 

  34. Clark SL, Cotton DB, Lee W et al (1989) Central hemodynamics of normal term pregnancy. Am J Obstet Gynecol 161:1439–1442

    PubMed  CAS  Google Scholar 

  35. Weir RJ, Brown JJ, Fraser R et al (1975) Relationship between plasma renin, renin-substrate, angiotensin II, aldosterone and electrolytes in normal pregnancy. J Clin Endocrinol Metab 40:108–115

    CAS  Google Scholar 

  36. Tauffield PA, Mueller FB, Edersheim TG et al (1988) Blood pressure regulation in normal pregnancy: unmasking the role of renin angiotensin system with captopril (abstract). Clin Res 36:433A

    Google Scholar 

  37. Gant NF, Daley GL, Chand S et al (1973) A study of angiotensin II pressor response throughout primigravid pregnancy. J Clin Invest 52:2682–2689

    Article  PubMed  CAS  Google Scholar 

  38. Rosenfeld CR (1989) Changes in uterine blood flow during pregnancy. In: Rosenfeld CR (ed) The uterine circulation. Perinatology Press, Ithaca, NY, pp 135–156

    Google Scholar 

  39. Massicotte G, St Louis T, Parent A et al (1987) Decreased in vitro response to vasoconstrictors during pregnancy in normotensive and spontaneously hypertensive pregnant rats. Can J Physiol Pharmacol 65: 2466–2471

    PubMed  CAS  Google Scholar 

  40. Naden RP, Rosenfeld CR (1981) Effect of angiotensin II on uterine and systemic vasculature in pregnant sheep. J Clin Invest 68:468–474

    Google Scholar 

  41. Moncada S, Gryglewski R, Bunting S et al (1976) An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibit platelet aggregation. Nature 263:663–665

    Article  PubMed  CAS  Google Scholar 

  42. Furchgott RF Zawadzki JV (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373–376

    Article  PubMed  CAS  Google Scholar 

  43. Furchgott RF, Vanhoutta PM (1989) Endothelium-derived relaxing and contracting factors. FASEB J 3: 2007–2018

    PubMed  CAS  Google Scholar 

  44. Palmer RMJ, Ferrig AG, Moncada S (1987) Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327:524–526

    Article  PubMed  CAS  Google Scholar 

  45. Ignarro LJ (1989) Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circ Res 65:1–21

    PubMed  CAS  Google Scholar 

  46. Gardiner SM, Compton AM, Bennett T et al (1990) Control of regional blood flow by endothelium-derived nitric oxide. Hypertension 15:486–492

    PubMed  CAS  Google Scholar 

  47. Ahokas RA, Sibai BM, Mabie MD et al (1988) Nifedipine does not adversely affect uteroplacental blood flow in the hypertensive term-pregnant rat. Am J Obstet Gynecol 159:1440–1445

    PubMed  CAS  Google Scholar 

  48. Greiss FC (1966) Pressure-flow relationship in the gravid uterine vascular bed. Am J Obstet Gynecol 96: 41–47

    PubMed  Google Scholar 

  49. Venuto RC, Cox JW, Stein JH et al (1976) The effect of changes in perfusion pressure on uteroplacental blood flow in the pregnant rabbit. J Chin Invest 57:938–944

    CAS  Google Scholar 

  50. Lindow SW, Davies N, Davey DA et al (1988) The effects of sublingual nifedipine on uteroplacental blood flow in hypertensive pregnancy. Br J Obstet Gynaecol 95:1276–1281

    PubMed  CAS  Google Scholar 

  51. Thaler I, Weiner Z, Manor D et al (1991) Effect of calcium channel blocker nifedipine on uterine artery flow velocity waveforms. J Ultrasound Med 10:301–304

    PubMed  CAS  Google Scholar 

  52. Landauer M, Phernetton TM, Parisi VM et al (1985) Ovine placental vascular response to the local application of prostacyclin. Am J Obstet Gynecol 151:460–464

    PubMed  CAS  Google Scholar 

  53. Husslein P, Gitch E, Pateisky N et al (1985) Prostacyclin does not influence placental blood flow in vivo. Gynecol Obstet Invest 19:78–81

    Article  PubMed  CAS  Google Scholar 

  54. Speroff L, Haning RV Jr, Levin RM (1977) The effect of angiotensin II and indomethacin on uterine artery blood flow in pregnant monkey. Obstet Gynecol 50: 611–614

    PubMed  CAS  Google Scholar 

  55. Weiner CP, Liu KZ, Thompson L et al (1991) Effect of pregnancy on endothelium and smooth muscle: their role in reduced adrenergic sensitivity. Am J Physiol 261:H1275–H1283

    PubMed  CAS  Google Scholar 

  56. Ylikorkala O, Makila UM (1985) Prostacyclin and thromboxane in gynecology and obstetrics. Am J Obstet Gynecol 152:318–329

    PubMed  CAS  Google Scholar 

  57. Magness RR, Osei-Boaten K, Mitchell MD et al (1985) In vitro prostacyclin production by ovine uterine and systemic arteries. J Chin Invest 76:2206–2212

    CAS  Google Scholar 

  58. Rakoczi I, Tihanyi K, Gero G et al (1988) Release of prostacyclin (PGIZ) from trophoblast in tissue culture: the effect of glucose concentration. Acta Physiol Hung 71:545–549

    PubMed  CAS  Google Scholar 

  59. Diss EM, Gabbe GS, Moore JW et al (1992) Study of thromboxane and prostacyclin metabolism in an in vitro model of first-trimester human trophoblast. Am J Obstet Gynecol 167:1046–1052

    PubMed  CAS  Google Scholar 

  60. Blumenstein M, Keelan JA, Mitchell MD (2001) Hypoxia attenuates PGE(2) but increases prostacyclin and thromboxane production in human term villous trophoblast. Placenta 22:519–525

    Article  PubMed  CAS  Google Scholar 

  61. Weiner CP, Martinez E, Chestnut DH et al (1989) Effect of pregnancy upon the uterine and carotid artery response to norepinephrine, epinephrine and phenylephrine in vessels with documented functional endothelium. Am J Obstet Gynecol 161:1605–1610

    PubMed  CAS  Google Scholar 

  62. Resnik R, Killman AP, Barton MD et al (1976) The effect of various vasoactive compounds upon the uterine vascular bed. Am J Obstet Gynecol 125:201–206

    PubMed  CAS  Google Scholar 

  63. Greiss FC Jr, Gabbe FL Jr, Anderson SG et al (1967) Effect of acetylcholine on the uterine vascular bed. Am J Obstet Gynecol 99:1073–1077

    PubMed  Google Scholar 

  64. Van Buren GA, Yang D, Clark KE (1992) Estrogen induced uterine vasodilation is antagonized by L-nitroarginine methyl ester, an inhibitor of nitric oxide synthesis. Am J Obstet Gynecol 167:828–833

    PubMed  Google Scholar 

  65. Molnar M, Hertelendy F (1992) Nw-nitro-L-arginine, an inhibitor of nitric oxide synthesis, increases blood pressure in rats and reverses the pregnancy-induced refractoriness to vasopressor agents. Am J Obstet Gynecol 166: 1560–1571

    PubMed  CAS  Google Scholar 

  66. Luscher TF (1990) The endothelium: target and promoter of hypertension? Hypertension 15:482–485

    PubMed  CAS  Google Scholar 

  67. Yanagisawa M, Kurihara H, Kimura S et al (1988) A novel potent vasoconstrictor-peptide produced by vascular endothelial cells. Nature 332:411–415

    Article  PubMed  CAS  Google Scholar 

  68. Katusie ZS, Vanhoutta PM (1989) Superoxide anion is an endothelium-derived contacting factor. Heart Circ Physiol 26:H33

    Google Scholar 

  69. Bodelsson G, Sjöberg NO, Stjernquist M (1992) Contactile effect of endothelium in human uterine artery and autoradiographic localization of its binding sites. Am J Obstet Gynecol 167:745–750

    PubMed  CAS  Google Scholar 

  70. Svane D, Larsson B, Aim P et al (1993) Endothelia-1: immunocytochemistry, localization of binding sites, and contractile effects in human uteroplacental smooth muscle. Am J Obstet Gynecol 168:233–241

    PubMed  CAS  Google Scholar 

  71. Taylor RN, Varma M, Nelson NHT et al (1990) Women with preeclampsia have higher plasma endothelia levels than women with normal pregnancies. J Chin Endocrinol Metab 71:1675–1677

    CAS  Google Scholar 

  72. Burns PN (1993) The physics of Doppler. In:Chervenak FA, Isaacson GC, Campbell S (eds) Ultrasound in obstetrics and gynecology. Little, Brown, Boston, pp 33–54

    Google Scholar 

  73. Thaler I, Bruck A (1991) Transvaginal sonography and Doppler measurements: physical considerations. In: Timor-Tritsch IE, Rottem S (eds) Transvaginal sonography. Elsevier, New York, pp 1–27

    Google Scholar 

  74. Thaler I, Manor D (1990) Transvaginal imaging: applied physical principles and terms. J Chin Ultrasound 18:235–238

    CAS  Google Scholar 

  75. Thaler I, Manor D, Rottem S et al (1990) Hemodynamic evaluation of the female pelvic vessels using a high-frequency ttansvaginal image-directed Doppler system. J Chin Ultrasound 18:364–369

    CAS  Google Scholar 

  76. Kurjak A, Jurkovic D, Alfirevic Z et al (1990) Transvaginal color Doppler imaging. J Chin Ultrasound 18:227–234

    CAS  Google Scholar 

  77. Thaler I, Manor D, Rottem S (1993) Transvaginal Doppler duplex system. In: Chervenak FA, Isaacson GC, Campbell S (eds) Ultrasound in obstetrics and gynecology. Little, Brown, Boston, pp 141–148

    Google Scholar 

  78. Bowere SJ, Campbell S (1993) Doppler velocimetry of the uterine artery as a screening test in pregnancy. In: Chervenak FA, Isaacson GC, Campbell S (eds) Ultrasound in obstetrics and gynecology. Little, Brown, Boston, pp 579–586

    Google Scholar 

  79. McCowan LM, Ritchie K, Mo LY et al (1988) Uterine artery flow velocity waveforms in normal and growth-retarded pregnancies. Am J Obstet Gynecol 158:499–504

    PubMed  CAS  Google Scholar 

  80. Pearce JM, Campbell S, Cohen-Overbeek TE et al (1988) Reference ranges and sources of variation for indices used to characterize flow velocity waveforms obtained by duplex, pulsed Doppler ultrasound from the uteroplacental and fetal circulation. Br J Obstet Gynaecol 95:248–256

    PubMed  CAS  Google Scholar 

  81. Hanretty KP, Primrose M, Neilson JP et al (1989) Pregnancy screening by Doppler uteroplacental and umbilical artery waveforms. Br J Obstet Gynaecol 96:1163–1167

    PubMed  CAS  Google Scholar 

  82. Juaniaux E, Jurkovic D, Campbell S et al (1991) Investigation of the placental circulation by color Doppler. Am J Obstet Gynecol 164:486–488

    Google Scholar 

  83. Thaler I, Weiner Z, Itskovitz J (1992) Systolic and diastolic notch in uterine artery blood flow velocity waveforms in hypertensive pregnant patients: relationship to outcome. Obstet Gynecol 80:277–282

    PubMed  CAS  Google Scholar 

  84. Bewley S, Campbell S, Cooper D (1989) Uteroplacental Doppler flow velocity waveforms in the second trimester: a complex circulation. Br J Obstet Gynaecol 90: 1040–1046

    Google Scholar 

  85. Deutinger J, Rudelstorfer R, Bernaschek G (1988) Vaginosonographic velocimetry of both uterine arteries by visual vessel recognition and pulsed Doppler method during pregnancy. Am J Obstet Gynecol 159:1072–1076

    PubMed  CAS  Google Scholar 

  86. Konje JC, Kaufmann P, Bell SC, Taylor DJ (2001) A longitudinal study of the quantification of uterine blood volume flow using colour power angiography in appropriate for gestational age pregnancies. Am J Obstet Gynecol 185:608–613

    Article  PubMed  CAS  Google Scholar 

  87. Arduini D, Rizzo G, Romanini C (1991) Doppler ultrasonography in early pregnancy does not predict adverse pregnancy outcome. Ultrasound Obstet Gynecol 1:180–185

    PubMed  CAS  Google Scholar 

  88. Jurkovic D, Jauniaux E, Kurjak A et al (1991) Transvaginal color Doppler assessment of uteroplacental blood flow in early pregnancy. Obstet Gynecol 77:365–369

    PubMed  CAS  Google Scholar 

  89. Jaffe R, Warsof SL (1991) Transvaginal color Doppler imaging in the assessment of uteroplacental blood flow in normal first-trimester pregnancy. Am J Obstet Gynecol 164:781–785

    PubMed  CAS  Google Scholar 

  90. Stabile I, Bilardo C, Panella M et al (1988) Doppler assessed uterine blood flow in the first trimester of pregnancy. Trophoblast Res 3:301–308

    Google Scholar 

  91. Den Ouden M, Cohen-Overbeek TE, Wladimiroff JW (1990) Uterine and fetal umbilical artery flow velocity waveforms in normal first trimester pregnancies. Br J Obstet Gynaecol 97:716–719

    Google Scholar 

  92. Stabile I, Grudzinskas J, Campbell S (1990) Doppler ultrasonographic evaluation of abnormal pregnancies in the first trimester. J Clin Ultrasound 18:497–501

    PubMed  CAS  Google Scholar 

  93. Thaler I, Tessler M, Itskovitz J (1991) Systolic and diastolic notch in uterine artery FVW in the first trimester of pregnancy: clinical significance. Presented at the 4th Congress of the International Perinatal Doppler Society, Malmo

    Google Scholar 

  94. Alfirevic Z, Kurjak A (1990) Transvaginal colour Doppler ultrasound in normal and abnormal early pregnancy. J Perinat Med 18:173–180

    Article  PubMed  CAS  Google Scholar 

  95. Makikallio K, Tekay A, Jouppila P (2001) Effects of bleeding on uteroplacental, umbilicoplacental and yolksac hemodynamics in early pregnancy. Ultrasound Obstet Gynecol 18:352–356

    Article  PubMed  CAS  Google Scholar 

  96. Kurjak A, Zalud I, Predanic M, Kupesic S (1994) Transvaginal color and pulsed Doppler study of uterine blood flow in the first and early second trimesters of pregnancy: normal versus abnormal. J Ultrasound Med 13: 43–47

    PubMed  CAS  Google Scholar 

  97. Pellizzari P, Pozzan C, Marchiory S, Zen T, Gangemi M (2002) Assessment of uterine artery blood flow in normal first-trimester pregnancies and in those complicated by uterine bleeding. Ultrasound Obstet Gynecol 19: 366–370

    Article  PubMed  CAS  Google Scholar 

  98. Jauniaux E, Zaidi J, Jurkovic D, Campbell S, Hustin J (1994) Comparison of colour Doppler features and pathological findings in complicated early pregnancy. Hum Reprod 9:2432–2437

    PubMed  CAS  Google Scholar 

  99. Coppens M, Loquet P, Kollen M, De Neubourg F, Buytaert P (1996) Longitudinal evaluation of uteroplacental and umbilical blood flow changes in normal early pregnancy. Ultrasound Obstet Gynecol 7:114–121

    Article  PubMed  CAS  Google Scholar 

  100. Jaffe R, Jauniaux E, Hustin J (1997) Maternal circulation in the first-trimester human placenta — myth or reality? Am J Obstet Gynecol 176:695–705

    Article  PubMed  CAS  Google Scholar 

  101. Simpson NA, Nimrod C, De Vermette R, Fournier J (1997) Determination of intervillous flow in early pregnancy. Placenta 18:287–293

    Article  PubMed  CAS  Google Scholar 

  102. Simpson NA, Nimrod C, De Vermette R, Leblanc C, Fournier J (1998) Sonographic evaluation of intervillous flow in early pregnancy: use of echo-enhancement agents. Ultrasound Obstet Gynecol 11:204–208

    Article  PubMed  CAS  Google Scholar 

  103. Kurjak A, Kupesic S (1998) Parallel Doppler assessment of yolk sac and intervillous circulation in normal pregnancy and missed abortion. Placenta 19:619–623

    PubMed  CAS  Google Scholar 

  104. Bude RO, van de Ven CJ, Rubin JM (1999) Transabdominal power Doppler sonography of the normal early placenta. Can Assoc Radiol J 50:255–259

    PubMed  CAS  Google Scholar 

  105. Alouini S, Carbillon L, Perrot N, Uzan S, Uzan M (2002) Intervillous and spiral artery flows in normal pregnancies between 5 and 10 weeks of amenorrhea using color Doppler ultrasonography. Fetal Diagn Ther 17: 163–166

    Article  PubMed  CAS  Google Scholar 

  106. Jauniaux E, Hempstock J, Greenwold N, Burton GJ (2003) Trophoblastic oxidative stress in relation to temporal and regional differences in maternal placental blood flow in normal and abnormal early pregnancies. Am J Pathol 162:115–125

    PubMed  Google Scholar 

  107. Giacobbe M, Zeferino LC, Franzin CM, Faundes A (2002) Uteroplacental circulation during the first trimester of normal and abnormal pregnancy. Reprod Biomed Online 4:62–67

    Article  PubMed  Google Scholar 

  108. Chesley LC (1978) Hypertensive disorders in pregnancy. Appleton-Century-Crofts, Norwalk, CT, p 225

    Google Scholar 

  109. Turnbull AC (1987) Maternal mortality and present trends. In: Sharp F, Symonds EM (eds) Hypertension in pregnancy. Perinatology Press, Ithaca, NY, p 135

    Google Scholar 

  110. MacGillivray I (1983) Preeclampsia: the hypertensive disease of pregnancy. Saunders, Philadelphia, p 17

    Google Scholar 

  111. Chiswick ML (1985) Intrauterine growth retardation. BMJ 291:845–848

    Article  PubMed  CAS  Google Scholar 

  112. Allen MC (1984) Developmental outcome and follow-up of the small for gestational age infant. Semin Perinatol 8:123–156

    PubMed  CAS  Google Scholar 

  113. Resnik R (1978) Maternal disease with abnormal, fetal growth. J Reprod Med 21:315

    PubMed  CAS  Google Scholar 

  114. Beaufils M, Uzan S, Donsimoni R et al (1985) Prevention of preeclampsia by early antiplatelet therapy. Lancet 1:840–842

    PubMed  CAS  Google Scholar 

  115. Andersen HG, Andersen LF, Fuchs AR (1989) Diet, preeclampsia and intrauterine growth retardation. Lancet 1:1146

    PubMed  CAS  Google Scholar 

  116. Kaar K, Jouppila P, Kuikka J et al (1980) Intervillous blood flow in normal and complicated late pregnancy measured by means of an intravenous 133Xe method. Acta Obstet Gynecol Scand 59:7–10

    Article  PubMed  CAS  Google Scholar 

  117. Nylund L, Lunell NO, Lewander R et al (1983) Uteroplacental blood flow index in intrauterine growth retardation of fetal and maternal origin. Br J Obstet Gynaecol 90:16–20

    PubMed  CAS  Google Scholar 

  118. Sheppard BL, Bonnar J (1976) The ultrastructure of the arterial supply of the human placenta in pregnancy complicated by fetal growth retardation. Br J Obstet Gynaecol 83:948–959

    PubMed  CAS  Google Scholar 

  119. McFayden IR, Price AB, Geirsson RT (1986) The relation of birthweight to histological appearance in vessels of the placental bed. Br J Obstet Gynaecol 93:476–481

    Google Scholar 

  120. Newnham JP, Patterson LL, James IR et al (1990) An evaluation of the efficacy of Doppler flow velocity waveform analysis as a screening test in pregnancy. Am J Obstet Gynecol 162:403–410

    PubMed  CAS  Google Scholar 

  121. Jacobson S-L, Imhof R, Manning N et al (1990) The value of Doppler assessment of the uteroplacental circulation in predicting preeclampsia or intrauterine growth retardation. Am J Obstet Gynecol 162:110–114

    PubMed  CAS  Google Scholar 

  122. Steel SA, Pearce JM, McFarland P et al (1990) Early Doppler ultrasound screening in prediction of hypertensive disorders of pregnancy. Lancet 1:1548–1551

    Google Scholar 

  123. Bewley S, Cooper D, Campbell S (1991) Doppler investigation of uteroplacental blood flow resistance in the second trimester: a screening study for preeclampsia and intrauterine growth retardation. Br J Obstet Gynaecol 98: 871–879

    PubMed  CAS  Google Scholar 

  124. Zimmermann P, Eirio V, Koskinen J, Kujansuu E, Harrington K (1997) Doppler assessment of the uterine and uteroplacental circulation in the second trimester in pregnancies at risk for pre-eclampsia and/or intrauterine growth retardation: comparison and correlation between different Doppler parameters. Ultrasound Obstet Gynecol 9: 330–338

    Article  PubMed  CAS  Google Scholar 

  125. Papageorghiou AT, Yu CKH, Bindra R, Pandis G, Nicolaides KH (2001) Multicenter screening for preeclampsia and fetal growth restriction by transvaginal uterine artery Doppler at 23 weeks of gestation. Ultrasound Obstet Gynecol 18:441–449

    PubMed  CAS  Google Scholar 

  126. Chien PF, Arnott N, Gordon A, Owen P, Khan SK (2000) How useful is uterine artery Doppler flow velocimetry in the prediction of preeclampsia, intrauterine growth retardation and perinatal death? An overview. Br J Obstet Gynaecol 107:196–208

    CAS  Google Scholar 

  127. Martin A, Bindra R, Curcio P, Cicero S, Nicolaides KH (2001) Screening for pre-eclampsia and fetal growth restriction by uterine artery Doppler at 11-14 weeks of gestation. Ultrasound Obstet Gynecol 18:583–586

    Article  PubMed  CAS  Google Scholar 

  128. Schuchter K, Metzenbauer M, Hafner E, Philipp K (2001) Uterine artery Doppler and placental volume in the first trimester in the prediction of pregnancy complications. Ultrasound Obstet Gynecol 18:590–592

    PubMed  CAS  Google Scholar 

  129. Gant NF, Worley RJ (1980) Hypertension in pregnancy. Appleton-Lange, Norfolk, CT, p 29

    Google Scholar 

  130. Zeeman GC, Dekker GA (1992) Pathogenesis of preeclampsia: a hypothesis. Chr Obstet Gynecol 35:317

    CAS  Google Scholar 

  131. Thaler I, Manor D, Brandes JM et al (1990) Basic principles and clinical applications of the transvaginal Doppler duplex system in reproductive medicine. J In Vitro Fertil Embryo Transfer 7:74

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, Ramban Medical Center, Haifa, 31096, Israel

    Israel Thaler MD & Amnon Amit MD

Authors
  1. Israel Thaler MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Amnon Amit MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Obstetrics and Gynecology, Winthrop University Hospital, 159 First Street, Mineola, NY, 11501, USA

    Dev Maulik MD, Ph.D.

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Thaler, I., Amit, A. (2005). Doppler Velocimetry of the Uteroplacental Circulation During Early Pregnancy. In: Maulik, D. (eds) Doppler Ultrasound in Obstetrics and Gynecology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28903-8_17

Download citation

  • DOI: https://doi.org/10.1007/3-540-28903-8_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-23088-5

  • Online ISBN: 978-3-540-28903-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation