Skip to main content
SpringerLink
Log in

Biochemical Status of Soft Tissues Subjected to Sustained Pressure

  • Chapter
Pressure Ulcer Research

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bouten CVC, Oomens CWJ, Baaijens FPT, Bader DL (2003) The aetiology of pressure sores: skin deep or muscle bound? Arch Phys Med Rehabil 84:616–619

    Article  PubMed  Google Scholar 

  2. Bliss MR (1993) Aetiology of pressure sores. Rev Clin Ger 3:379–397

    Google Scholar 

  3. Krouskop TA, Reddy NP, Spencer W, Secor J (1978) Mechanisms of decubitus ulcer formation. Med Hypotheses 4:37–39

    Article  PubMed  CAS  Google Scholar 

  4. Bouten CVC, Lee DA, Knight MM, Bader DL (2001) Compressive deformation and damage of muscle cell sub-populations in a model system. J Biomech Eng 29:153–163

    CAS  Google Scholar 

  5. Schubert V, Fagrell B (1991) Post-occlusive reactive hyperaemia and thermal response in the skin microcirculation of subjects with spinal cord injury. Scand J Rehabil Med 23:33–45

    PubMed  CAS  Google Scholar 

  6. Hagisawa S, Ferguson-Pell M, Cardi M, Miller SD (1994) Assessment of skin blood content and oxygenation in spinal injured subjects during reactive hyperaemia. J Rehabil Res Dev 31:1–14

    PubMed  CAS  Google Scholar 

  7. Ferguson-Pell M, Hagisawa S (1995) An empirical technique to compensate for melanin when monitoring skin microcirculation using reflectance spectrophotometry. Med Eng Phy 7:104–110

    Google Scholar 

  8. Newson TP, Rolfe P (1982) Skin surface P02 and blood flow measurements over the ischial tuberosities. Arch Phys Med Rehabil 63:553–556

    PubMed  CAS  Google Scholar 

  9. Bader DL, Gant CA (1988) Changes in transcutaneous oxygen tension as a result of prolonged pressures at the sacrum. Clin Phys Physiol Meas 9:33–40

    Article  PubMed  CAS  Google Scholar 

  10. Bader DL (1990) The recovery characteristics of soft tissue following repeated loading. J Rehabil Res Dev 27, 141–150

    PubMed  CAS  Google Scholar 

  11. Bader DL (1990) Effects of compressive load regimens on tissue viability. In: Bader DL (ed) Pressure sores — clinical practice and scientific approach. Macmillan, Basingstoke, pp 191–201

    Google Scholar 

  12. Colin D, Saumet JL (1996) Influence of external pressure on transcutaneous oxygen tension and laser Doppler flowmetry on sacral skin. Clin Physiol 16:61–72

    PubMed  CAS  Google Scholar 

  13. Colin D, Loyant R, Abraham P, Saumet JL (1996) Changes in sacral transcutaneous oxygen tension in the evaluation of different mattresses in the prevention of pressure ulcers. Adv Wound Care 9:25–28

    PubMed  CAS  Google Scholar 

  14. Bogie KM, Nuseibeh I, Bader DL (1995) Early progressive changes in tissue viability in the seated spinal cord injured subject. Paraplegia 33:1441–1447

    Google Scholar 

  15. Van Heyningen R, Weiner JS (1952) The effect of arterial occlusion on sweat composition. Physiology 116:404–413

    Google Scholar 

  16. Hagisawa S, Ferguson-Pell M, Cardi M, Miller SD (1988) Biochemical changes in sweat following pressure ischaemia J Rehab Res Dev 25:57–62

    Google Scholar 

  17. Polliack AA, Taylor RP, Bader DL (1993) The analysis of sweat during soft tissue breakdown following pressure ischaemia. J Rehab Res Dev 30(2):250–259

    CAS  Google Scholar 

  18. Polliack AA, Taylor RP, Bader DL (1997) Sweat analysis following pressure ischaemia in a group of debilitated subjects. J Rehab Res Dev 34(3):303–308

    CAS  Google Scholar 

  19. Taylor RP, Polliack AA, Bader DL (1994) The analysis of metabolites in human sweat: analytical methods and potential application to investigation of pressure ischaemia of soft tissues. Ann Clin Biochem 31:18–24

    PubMed  CAS  Google Scholar 

  20. Knight SL (1997) Non-invasive techniques for predicting soft tissue status during pressure induced ischaemia. PhD thesis, Queen Mary, University of London.

    Google Scholar 

  21. Knight SL, Taylor RP, Polliack AA, Bader DL (2001) Establishing predictive indicators for the status of soft tissues. J Appl Physiol 90:2231–2237

    PubMed  CAS  Google Scholar 

  22. Sato K (1977) The physiology, pharmacology and biochemistry of the eccrine sweat gland. Rev Physiol Biochem Pharmacol 79:51–131

    PubMed  CAS  Google Scholar 

  23. Sato K, Dobson RL (1973) Glucose metabolism of the isolated eccrine sweat gland. J Clin Investig 5:2166–2174

    Google Scholar 

  24. Komives GK, Robinson S, Roberts JT (1966) Urea transfer across sweat glands. J Appl Physiol 21:1681–1684

    PubMed  CAS  Google Scholar 

  25. Whitehouse AGR (1935) Dissolved constituents of human sweat. Proc R Soc Lond B 117:139–154

    Article  CAS  Google Scholar 

  26. Schwartz IL, Thaysen JH, Dole VP (1955) Urea secretion in human sweat as a tracer for movement of water within the secreting gland. J Exp Med 97:429–437

    Google Scholar 

  27. Fox IH, Palella TD, Kelly WN (1987) Hyperuricemia: A marker for cell energy crisis. N Engl J Med 317(2):111–112

    Article  PubMed  CAS  Google Scholar 

  28. Grum CM, Simon RH, Dantzker DR, Fox IH (1985) Evidence for adenosine triphosphate degradation in critically ill patients. Chest 88:763–767

    PubMed  CAS  ISI  Google Scholar 

  29. Kock R, Delvoux B, Sigmund M, Greiling H (1994) A comparative study of the concentrations of hypoxanthine, xanthine, uric acid, and allantoin, in the peripheral blood of normal and patients with acute myocardial infarction and other ischaemic disorders. Eur J Clin Chem Clin Biochem 32:837–842

    PubMed  CAS  Google Scholar 

  30. Granger DN, Korthuis RJ (1995) Physiological mechanisms of post-ischemic tissue injury. Annu Rev Physiol 57:311–332

    PubMed  CAS  Google Scholar 

  31. Wang Y-N (2000) The response of soft tissues to mechanical loads at different structural levels and the implications in their breakdown. PhD thesis, Queen Mary, University of London

    Google Scholar 

  32. Gutman I, Wahlefeld AW (1974) L-(+)-Lactate determination with lactic dehydrogenase and NAD. In: Bergmeyer HU (ed) Methods of enzymatic analysis, 2nd English edn. Verlag Chemie/AP, Weinheim, pp 1464–1468

    Google Scholar 

  33. Bennett MJ, Carpenter KH (1984) Experience with a simple high-performance liquid chromatography method for the analysis of purine and pyrimidine nucleosides and bases in biological fluids. Ann Clin Biochem 21:131–136

    PubMed  CAS  Google Scholar 

  34. Kaldor G, DiBattista WJ (1978) Isoproterenol effects on hearts of ageing rats. Aging 6:101–140

    CAS  Google Scholar 

  35. Woolliscroft JO, Fox IH (1986) Increased body fluid purine levels during hypotensive events: Evidence for ATP degradation. Am J Med 81:472–478

    Article  PubMed  CAS  Google Scholar 

  36. Hyman WA, Artigue RS (1977) Oxygen and lactic acid transport in skeletal muscles. effect of reactive hyperaemia. Ann Biomed Eng 5:260–266

    PubMed  CAS  Google Scholar 

  37. Krouskop TA, Reddy NP, Spencer WA, Secor JW (1978) Mechanisms of decubitus ulcer formation: an hypothesis. Med Hypotheses 4:37–39

    Article  PubMed  CAS  Google Scholar 

  38. Miller GE, Seal JL (1985) The mechanics of terminal lymph flow. J Biomech Eng 107:376–380

    Article  PubMed  CAS  Google Scholar 

  39. Oredsson S, Plate G, Qvarfordt P (1991) Allopurinol-A free-radical scavenger reduces reperfusion injury in skeletal muscle. Eur J Vasc Surg 5:47–52

    Article  PubMed  CAS  Google Scholar 

  40. McCord JM (1985) Oxygen-derived free radicals in postischaemic tissue injury. N Engl J Med 312:159–163

    PubMed  CAS  Google Scholar 

  41. Walubo A, Smith PJ, Folb PI (1995) Oxidative stress during anti-tuberculosis therapy in young and elderly patients. Biomed Environ Sci 8:106–113

    PubMed  CAS  Google Scholar 

  42. Moison RMW, De Beaufort AJ, Haasnoot AA, Dubbelman TMAR, Van Zoeren-Grobbea D, Berger HM (1997) Uric acid and ascorbic acid redox ratios in plasma and tracheal aspiration of preterm babies with acute and chronic lung disease. Free Radical Biol Med 23:226–234

    Article  CAS  Google Scholar 

  43. McCance RA, Puroait G (1969) Ethnic differences in the response of sweat glands to pilocarpine. Nature 221:378–379

    PubMed  CAS  ISI  Google Scholar 

  44. Cage GW, Wolfe SM, Thompson RH, Gordon RS (1970) Effects of water intake on composition of thermal sweat in normal human volunteers. J Appl Physiol 29:687–690

    PubMed  CAS  Google Scholar 

  45. Dewasmes G, Bothokel B, Hoeft A, Candas V (1993) Regulation of local sweating in sleep-derived exercising humans. Eur J ApplPhysiol 66:542–546

    CAS  Google Scholar 

  46. Laccourreye O, Bernard D, de Lacharriere O, Bazin R, Brasnn D (1993) Frey’s syndrome analysis with biosensor. Arch Otolaryngol Head Neck Surg 119:940–944

    PubMed  CAS  Google Scholar 

  47. Mitsubayashi K, Suzuki M, Tamiya E, Karube I (1994) Analysis of metabolites in sweat as a measure of physical condition. Anal Chem Acta 289:27–34

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Engineering & IRC in Biomedical Materials, Queen Mary University of London, Mile End Road, London, E1 4NS, UK

    Dan Bader

  2. Department of Bioengineering, University of Washington, 357962, Harris 309, Seattle, WA, USA

    Yak-Nam Wang

  3. Spinal Research Centre, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, HA7 4LP, UK

    Sarah Knight

  4. Department of Clinical Biochemistry, Oxford Radcliffe Hospital, Headington, Oxford, OX3 1XX, UK

    Adrian Polliack & Tim James

  5. Department of Clinical Biochemistry, Oxford Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK

    Richard Taylor

Authors
  1. Dan Bader
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yak-Nam Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sarah Knight
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Adrian Polliack
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Tim James
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Richard Taylor
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Engineering & IRC in Biomedical Materials, Queen Mary University of London, Mile End Road, London, E1 4NS, UK

    Dan L. Bader PhD, DSc

  2. Biomedical Engineering Department, Eindhoven University of Technology, Den Dolech 2, P/O Box 513, 5600 MB, Eindhoven, The Netherlands

    Carlijn V.C. Bouten PhD  & Cees W.J. Oomens PhD  & 

  3. Rehabilitation Hospital, Centre de l’Arche, 72650, Saint Saturnin, Le Mans, France

    Denis Colin MD (Medical Director) (Medical Director)

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Bader, D., Wang, YN., Knight, S., Polliack, A., James, T., Taylor, R. (2005). Biochemical Status of Soft Tissues Subjected to Sustained Pressure. In: Bader, D.L., Bouten, C.V., Colin, D., Oomens, C.W. (eds) Pressure Ulcer Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28804-X_8

Download citation

  • DOI: https://doi.org/10.1007/3-540-28804-X_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-25030-2

  • Online ISBN: 978-3-540-28804-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation