Conclusion
In our group of patients with hemophilia we have not found carriers of homozygous prothrombotic gene mutations. Heterozygous defects were found only. There was no influence on clinical phenotype in single defects. We observed a statistically insignificant effect on clinical phenotype in combined defects. Our experience is limited by the small group of patients under examination. The clinical phenotype may also be influenced by other factors than those involving clot formation. Further studies are needed to confirm an exact role of prothrombotic factors.
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© 2006 Springer Verlag Berlin Heidelberg
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Hluší, A., Krčová, V., Novák, P., Slavík, L. (2006). Hemophilia Patients and Prothrombotic Gene Mutation. In: Scharrer, I., Schramm, W. (eds) 35th Hemophilia Symposium. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28546-6_45
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DOI: https://doi.org/10.1007/3-540-28546-6_45
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