Skip to main content
SpringerLink
Log in

Pathogenese, Epidemiologie und Klassifikation des diabetischen Fußsyndroms

  • Chapter
Der diabetische Fuß

  • 890 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Consensus Development Conference on Diabetic Foot Wound Care. 7.–8. April 1999, Boston, Massachusetts. American Diabetes Association. J Am Podiatr Med Assoc 89: 475–483

    Google Scholar 

  2. Peripheral arterial disease in people with Diabetes (2003) Diabetes Care 26: 3333–3341

    Google Scholar 

  3. Abbott CA, Carrington AL, Ashe H et al. (2002) The North-West Diabetes Foot Care Study: incidence of, and risk factors for, new Diabetic foot ulceration in a community-based patient cohort. Diabet Med 19: 377–384

    Article  PubMed  Google Scholar 

  4. Abbott CA, Vileikyte L, Williamson S, Carrington AL, Boulton AJ (1998) Multicenter study of the incidence of and predictive risk factors for Diabetic neuropathic foot ulceration. Diabetes Care 21: 1071–1075

    PubMed  Google Scholar 

  5. Adler A (2001) Risk factors for Diabetic neuropathy and foot ulceration. Curr Diab Rep 1:202–207

    PubMed  Google Scholar 

  6. Adler AI, Boyko EJ, Ahroni JH, Smith DG (1999) Lower-extremity amputation in Diabetes. The independent effects of peripheral vascular disease, sensory neuropathy, and foot ulcers. Diabetes Care 22: 1029–1035

    PubMed  Google Scholar 

  7. Ahroni JH, Boyko EJ, Forsberg RC (1999) Clinical correlates of plantar pressure among Diabetic veterans. Diabetes Care 22: 965–972

    PubMed  Google Scholar 

  8. Akbari CM, Logerfo FW (1999) Diabetes and peripheral vascular disease. J Vasc Surg 30: 373–384

    PubMed  Google Scholar 

  9. Apelqvist J, Larsson J, Agardh CD (1993) Long-term prognosis for Diabetic patients with foot ulcers. J Intern Med 233: 485–491

    PubMed  Google Scholar 

  10. Arlt B, Protze J (1997) Diabetic foot. Langenbecks Arch. Chir Suppl Kongressbd 114: 528–532

    Google Scholar 

  11. Armstrong DG, Lavery LA, Harkless LB (1998) Validation of a Diabetic wound classification system. The contribution of depth, infection, and ischemia to risk of amputation. Diabetes Care 21: 855–859

    PubMed  Google Scholar 

  12. Armstrong DG, Lavery LA, Harkless LB (1998) Who is at risk for Diabetic foot ulceration? Clin Podiatr Med Surg 15: 11–19

    PubMed  Google Scholar 

  13. Arora S, Logerfo FW (1997) Lower extremity macrovascular disease in Diabetes. J Am Podiatr Med Assoc 87: 327–331

    PubMed  Google Scholar 

  14. Arora S, Pomposelli F, Logerfo FW, Veves A (2002) Cutaneous microcirculation in the neuropathic Diabetic foot improves significantly but not completely after successful lower extremity revascularization. J Vasc Surg 35: 501–505

    Article  PubMed  Google Scholar 

  15. Basit A, Hydrie MZ, Hakeem R., Ahmedani MY, Masood Q (2004): Frequency of chronic complications of type II Diabetes. J Coll. Physicians Surg Pak. 14: 79–83

    PubMed  Google Scholar 

  16. Benotmane A, Mohammedi F, Ayad F et al. (2001) Management of Diabetic foot lesions in hospital: costs and benefits. Diabetes Metab 27:688–694

    PubMed  Google Scholar 

  17. Boulton AJ (2000) The Diabetic foot: a global view. Diabetes Metab Res Rev 16Suppl 1: S2–S5

    Article  PubMed  Google Scholar 

  18. Boulton AJ, Kirsner RS, Vileikyte L (2004) Clinical practice. Neuropathic Diabetic foot ulcers. N Engl J Med 351:48–55

    Article  PubMed  Google Scholar 

  19. Boulton AJ, Meneses P, Ennis WJ (1999) Diabetic foot ulcers: A framework for prevention and care. Wound Repair Regen 7: 7–16

    Article  PubMed  Google Scholar 

  20. Bowering CK (2001) Diabetic foot ulcers. Pathophysiology, assessment, and therapy. Can Fam Physician 47:1007–1016

    PubMed  Google Scholar 

  21. Boyko EJ, Ahroni JH, Stensel V et al. (1999) A prospective study of risk factors for Diabetic foot ulcer. The Seattle Diabetic Foot Study. Diabetes Care 22: 1036–1042

    PubMed  Google Scholar 

  22. Brem H, Sheehan P, Boulton AJ (2004) Protocol for treatment of Diabetic foot ulcers. Am J Surg 187: 1S–10S

    Article  PubMed  Google Scholar 

  23. Burns SL, Leese GP, McMurdo ME (2002) Older people and ill fitting shoes. Postgrad Med J 78: 344–346

    Article  PubMed  Google Scholar 

  24. Caselli A, Pham H, Giurini JM., Armstrong DG, Veves A (2002) The forefoot-to-rearfoot plantar pressure ratio is increased in severe Diabetic neuropathy and can predict foot ulceration. Diabetes Care 25: 1066–1071

    PubMed  Google Scholar 

  25. Day MR, Harkless LB (1997) Factors associated with pedal ulceration in patients with Diabetes mellitus. J Am Podiatr Med Assoc 87: 365–369

    PubMed  Google Scholar 

  26. Delbridge L, Ctercteko G, Fowler C, Reeve TS, Le Quesne LP (1985) The aetiology of Diabetic neuropathic ulceration of the foot. Br J Surg 72: 1–6

    PubMed  Google Scholar 

  27. Diabetes care and research group in Europe (1990) The Saint Vincent Declaration. Diabet Med 7: 360

    Google Scholar 

  28. Dyck P, Karnes JL, O'Brien P et al. (1992) The Rochester Diabetic Neuropathy Study: Reassessment of tests and criteria for diagnosis and staged severity. Neurology 42: 1164–1170

    PubMed  Google Scholar 

  29. Faglia E, Favales F, Morabito A (2001) New ulceration, new major amputation, and survival rates in Diabetic subjects hospitalized for foot ulceration from 1990 to 1993: a 6.5-year follow-up. Diabetes Care 24: 78–83

    PubMed  Google Scholar 

  30. Forst T, Kann P, Pfuetzner A et al. (1994) Association between «Diabetic thick skin syndrome» and neurological disorders in Diabetes mellitus. Acta Diabetol 31: 73–77

    Article  PubMed  Google Scholar 

  31. Forst T, Pfuetzner A, Kann P et al. (1995) Association between Diabetic-autonomic-C-fibre-neuropathy and medial wall calcification and the significance in the outcome of trophic foot lesions. Exp Clin Endocrinol Diabetes 103: 94–98

    PubMed  Google Scholar 

  32. Forst T, Pfuetzner A, Kann P et al. (1995) Association between Diabetic-autonomic-C-fibre-neuropathy and medial wall calcification and the significance in the outcome of trophic foot lesions. Exp Clin Endocrinol Diabetes 103: 94–98

    PubMed  Google Scholar 

  33. Forst T, Pfutzner A (2004) Risikofaktor für das Diabetische Fußsyndrom: Autonome Dysfunktion an der unteren Extremität. MMW Fortschr Med 146: 35–38

    Google Scholar 

  34. Frykberg RG, Arora S, Pomposelli FB Jr, LoGerfo F (1998) Functional outcome in the elderly following lower extremity amputation. J Foot Ankle Surg 37: 181–185

    PubMed  Google Scholar 

  35. Frykberg RG, Lavery LA, Pham H et al. (1998) Role of neuropathy and high foot pressures in Diabetic foot ulceration. Diabetes Care 21: 1714–1719

    PubMed  Google Scholar 

  36. Gilmore JE, Allen JA, Hayes JR (1993) Autonomic function in neuropathic Diabetes patients with foot ulceration. Diabetes Care 16/1: 61–67

    Google Scholar 

  37. Girod I, Valensi P, Laforet C et al. (2003) An economic evaluation of the cost of Diabetic foot ulcers: results of a retrospective study on 239 patients. Diabetes Metab 29: 269–277

    PubMed  Google Scholar 

  38. Harrington C, Zagari MJ, Corea J, Klitenic J (2000) A cost analysis of Diabetic lower-extremity ulcers. Diabetes Care 23: 1333–1338

    PubMed  Google Scholar 

  39. Heller G, Gunster C, Schellschmidt H (2004) Wie häufig sind Diabetes-bedingte Amputationen der unteren Extremität in Deutschland? Dtsch Med Wochenschr 129: 429–433

    Article  PubMed  Google Scholar 

  40. Hile C, Veves A (2003) Diabetic neuropathy and microcirculation. Curr Diab Rep 3: 446–451

    PubMed  Google Scholar 

  41. Holstein P, Ellitsgaard N, Olsen BB, Ellitsgaard V (2000) Decreasing incidence of major amputations in people with Diabetes. Diabetologia 43: 844–847

    Article  PubMed  Google Scholar 

  42. Holzer SE, Camerota A, Martens L et al. (1998) Costs and duration of care for lower extremity ulcers in patients with Diabetes. Clin Ther 20: 169–181

    Article  PubMed  Google Scholar 

  43. Kalani M, Brismar K, Fagrell B, Ostergren J, Jorneskog G (1999) Transcutaneous oxygen tension and toe blood pressure as predictors for outcome of Diabetic foot ulcers. Diabetes Care 22: 147–151

    PubMed  Google Scholar 

  44. Kraus O, Neufang A, Eckardt A et al. (2002) Interdisziplinäre Diagnostik und Therapie des ischämisch-osteomyelitischen Diabetischen Fußsyndroms. Med Klin 97:244–255

    Article  PubMed  Google Scholar 

  45. Larsson J, Agardh CD, Apelqvist J, Stenstrom A (1998) Long-term prognosis after healed amputation in patients with Diabetes. Clin Orthop 350: 149–158

    PubMed  Google Scholar 

  46. Lavery LA, Armstrong DG, Vela SA, Quebedeaux TL, Fleischli JG (1998) Practical criteria for screening patients at high risk for Diabetic foot ulceration. Arch Intern Med 158: 157–162

    Article  PubMed  Google Scholar 

  47. Lavery LA, van Houtum WH, Harkless LB (1996) In-hospital mortality and disposition of Diabetic amputees in The Netherlands. Diabet Med 13: 192–197

    Article  PubMed  Google Scholar 

  48. Liebl A, Neiss A, Spannheimer A et al (2001) Kosten des Typ-2 Diabetes in Deutschland. Dtsch Med Wochenschr 126: 585–589

    Article  PubMed  Google Scholar 

  49. Litzelman DK, Marriott DJ, Vinicor F (1997) Independent physiological predictors of foot lesions in patients with NIDDM. Diabetes Care 20: 1273–1278

    PubMed  Google Scholar 

  50. Lobmann R (1999) Ätiopathogenese und Diagnostik des Diabetischen Fußsyndroms. Diab & Stoffw 8/Suppl 5: 5–8

    Google Scholar 

  51. Lobmann R, Schultz G, Lehnert H (20039 Molekulare Grundlagen der Wundheilung beim daibetischen Fußsyndrom. Med Klin 98: 292–301

    Article  PubMed  Google Scholar 

  52. Logerfo FW, Gibbons GW, Pomposelli FB Jr et al. (1992) Trends in the care of the Diabetic foot Expanded role of arterial reconstruction. Arch Surg 127: 617–620

    PubMed  Google Scholar 

  53. Lynch SE, Colvin RB, Antoniades HN (1989) Growth factors in wound healing. Single and synergistic effects on partial thickness porcine skin wounds. Journal of Clinical Investigation 84: 640–646

    PubMed  Google Scholar 

  54. Macfarlane RM, Jeffcoate WJ (1997) Factors contributing to the presentation of Diabetic foot ulcers. Diabet Med 14: 867–870

    Article  PubMed  Google Scholar 

  55. Mast BA, Schultz GS (1996) Interactions of cytokines, growth factors and proteasesin acute and chronic wounds. Wound. Repair Regen 4: 441–420

    Article  Google Scholar 

  56. Mayfield JA, Caps MT, Boyko EJ, Ahroni JH, Smith DG (2002) Relationship of medial arterial calcinosis to autonomic neuropathy and adverse outcomes in a Diabetic veteran population. J Diabetes Complications 16: 165–171

    Article  PubMed  Google Scholar 

  57. Mayfield JA, Reiber GE, Sanders LJ, Janisse D, Pogach LM (2003) Preventive foot care in people with Diabetes. Diabetes Care 26Suppl 1: S78–S79

    PubMed  Google Scholar 

  58. McFadden JP., Corrall RJM, O'Brien IAD (1991) Autonomic and sensory nerve function in Diabetic foot ulceration. Clin Exp Dermatol 16: 193–196

    PubMed  Google Scholar 

  59. Meijer JW, Bosma E, Lefrandt JD et al. (2003) Clinical diagnosis of Diabetic polyneuropathy with the Diabetic neuropathy symptom and Diabetic neuropathy examination scores. Diabetes Care 26: 697–701

    PubMed  Google Scholar 

  60. Meyer-Heintze V (1999) Der Diabetische Fuß aus sozialmedizinischer Sicht Zentralbl Chir 124Suppl 1: 45–48

    Google Scholar 

  61. Morris AD, McAlpine R, Steinke D et al. (1998) Diabetes and lower-limb amputations in the community. A retrospective cohort study. DARTS/MEMO Collaboration. Diabetes Audit and Research in Tayside Scotland/Medicines Monitoring Unit Diabetes Care 21: 738–743

    Google Scholar 

  62. Moss SE, Klein R, Klein BE (1999) The 14-year incidence of lower-extremity amputations in a Diabetic population. The Wisconsin Epidemiologic Study of Diabetic Retinopathy Diabetes Care 22: 951–959

    Google Scholar 

  63. Moulik PK, Mtonga R, Gill GV (2003) Amputation and mortality in new-onset Diabetic foot ulcers stratified by etiology. Diabetes Care 26: 491–494

    PubMed  Google Scholar 

  64. Nwomeh BC, Yager DR, Cohen IK (1998) Physiology of the chronic wound. Clin Plast Surg 25: 341–356

    PubMed  Google Scholar 

  65. O'Brien SP, Schwedler M, Kerstein MD (1998) Peripheral neuropathies in Diabetes. Surg Clin North Am 78: 393–408

    Article  PubMed  Google Scholar 

  66. Ollendorf DA, Kotsanos JG, Wishner WJ et al. (1998) Potential economic benefits of lower-extremity amputation prevention strategies in Diabetes. Diabetes Care 21: 1240–1245

    PubMed  Google Scholar 

  67. Oyibo SO, Jude EB, Tarawneh I et al. (2001) A comparison of two Diabetic foot ulcer classification systems: the Wagner and the University of Texas wound classification systems. Diabetes Care 24: 84–88

    PubMed  Google Scholar 

  68. Padberg FT, Back TL, Thompson PN, Hobson RW (1996) Transcutaneous oxygen (TcpO2) estimates probability of healing in the ischemic extremity. J Surg Res 60: 365–369

    Article  PubMed  Google Scholar 

  69. Pfutzner A, Forst T, Engelbach M et al. (2001) The influence of isolated small nerve fibre dysfunction on microvascular control in patients with Diabetes mellitus. Diabet Med 18: 489–494

    Article  PubMed  Google Scholar 

  70. Pham HT, Economides PA, Veves A (1998) The role of endothelial function on the foot Microcirculation and wound healing in patients with Diabetes. Clin Podiatr Med Surg 15: 85–93

    PubMed  Google Scholar 

  71. Ramsey SD, Newton K, Blough D et al. (1999) Incidence, outcomes, and cost of foot ulcers in patients with Diabetes. Diabetes Care 22: 382–387

    PubMed  Google Scholar 

  72. Reiber GE, Lipsky BA, Gibbons GW (1998) The burden of Diabetic foot ulcers. Am J Surg 176: 5S–10S

    Article  PubMed  Google Scholar 

  73. Schaper NC, Apelqvist J, Bakker K (2003) The international consensus and practical guidelines on the management and prevention of the Diabetic foot Curr. Diab Rep 3: 475–479

    PubMed  Google Scholar 

  74. Shaw JE, Boulton AJ (1997) The pathogenesis of Diabetic foot problems: an overview. Diabetes 46Suppl 2:S58–S61

    PubMed  Google Scholar 

  75. Sims DS Jr, Cavanagh PR, Ulbrecht JS (1988) Risk factors in the Diabetic foot Recognition and management Phys Ther 68: 1887–1902

    PubMed  Google Scholar 

  76. Sosenko JM, Sparling YH, Hu D et al. (1999) Use of the Semmes-Weinstein monofilament in the strong heart study. Risk factors for clinical neuropathy. Diabetes Care 22: 1715–1721

    PubMed  Google Scholar 

  77. Sumpio BE, Lee T, Blume PA (2003) Vascular evaluation and arterial reconstruction of the Diabetic foot Clin Podiatr Med Surg 20: 689–708

    Article  PubMed  Google Scholar 

  78. Tarnuzzer RW, MacAuley S, Bruce M et al. (1995) Epidermal growth factor in wound healing: A model for molecular pathogenesis of chronic wounds. Serono Symposia

    Google Scholar 

  79. Tarnuzzer RW, Schultz GS (1996) Biochemical analysis of acute and chronic wound environments. Wound. Repair Regen 4: 321–325

    Article  Google Scholar 

  80. Trautner C, Haastert B, Giani G, Berger M (1996) Incidence of lower limb amputations and Diabetes. Diabetes Care 19/9: 1006–1009

    Google Scholar 

  81. Trautner C, Haastert B, Spraul M, Giani G, Berger M (2001) Unchanged incidence of lower-limb amputations in a German City, 1990–1998. Diabetes Care 24: 855–859

    PubMed  Google Scholar 

  82. Trautner C, Standl E, Haastert B, Giani G, Berger M (1997) Geschätzte Anzahl von Amputationen in Deutschland. Diab & Stoffw 6: 199–202

    Google Scholar 

  83. Trengove NJ, Bielefeldt-Ohmann H, Stacey MC (2000) Mitogenic activity and cytokine levels in non-healing and healing chronic leg ulcers. Wound. Repair Regen 8: 13–25

    Article  PubMed  Google Scholar 

  84. Trengove NJ, Stacey MC, MacAuley S et al. (1999) Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors. Wound. Repair Regen 7: 442–452

    Article  PubMed  Google Scholar 

  85. Uccioli L, Mancini L, Giordano A et al. (1992) Lower limb arterio-venous shunts, autonomic neuropathy and Diabetic foot Diabetes Res Clin PracT 16: 123–130

    Article  PubMed  Google Scholar 

  86. Van Gils CC, Wheeler LA, Mellstrom M et al. (1999) Amputation prevention by vascular surgery and podiatry collaboration in high-risk Diabetic and nonDiabetic patients. The Operation Desert Foot experience. Diabetes Care 22: 678–683

    PubMed  Google Scholar 

  87. Veves A, Murray HJ, Young MJ, Boulton AJM (1992) The risk of foot ulceration in Diabetic patients with high foot pressure: a prospective study. Diabetologia 35: 660–663

    Article  PubMed  Google Scholar 

  88. Wagner FW (1981) The dysvascular foot: a system for diagnosis and treatment. Foot & Ancle 2: 64–122

    Google Scholar 

  89. Walsh SM, Sage RA (2002) Depression and chronic Diabetic foot disability. A case report of suicide Clin Podiatr Med Surg 19: 493–508

    Article  PubMed  Google Scholar 

  90. Warren G (2002) Practical management of neuropathic feet Trop Doct 32: 201–205

    PubMed  Google Scholar 

  91. Winkler AS, Ejskjaer N, Edmonds M, Watkins PJ (2000) Dissociated sensory loss in Diabetic autonomic neuropathy. Diabet Med 17: 457–462

    Article  PubMed  Google Scholar 

  92. Yager DR, Zhang Y, Liang H-X, Diegelmann RF, Cohen IK (1996) Wound fluids from human pressure ulcers contain elevated matrix metalloproteinase levels and activity compared to surgical wound fluids. J Invest Dermatol 107: 743–748

    Article  PubMed  Google Scholar 

Download references

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer Medizin Verlag Heidelberg

About this chapter

Cite this chapter

(2005). Pathogenese, Epidemiologie und Klassifikation des diabetischen Fußsyndroms. In: Der diabetische Fuß. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27609-2_1

Download citation

  • DOI: https://doi.org/10.1007/3-540-27609-2_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-22719-9

  • Online ISBN: 978-3-540-27609-8

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation