This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Seno H, Suzuki O, Kumazawa T et al. (1989) Rapid isolation with Sep-Pak C18 cartridges and wide-bore capillary gas chromatography of some butyrophenones. Z Rechtsmed 102:127–132
Tyndale RF, Inaba T (1990) Simultaneous determination of haloperidol and reduced haloperidol by gas chromatography using a megabore column with electron capture detection: application to microsomal oxidation of reduced haloperidol. J Chromatogr 529:182–188
Ulrich S, Meyer FP, Neuhof S et al. (1995) Megabore capillary gas-liquid chromatographic method with nitrogen-phosphorus selective detection for the assay of haloperidol and reduced haloperidol in serum: results of therapeutic drug-monitoring during acute therapy of eight schizophrenics. J Chromatogr B 663:289–296
Tokunaga H, Kudo K, Imamura T (1996) Screening of antipsychotic drugs by wide-bore capillary gas chromatography with nitrogen phosphorus detection. Jpn J Legal Med 50:196–202
Hattori H, Suzuki O, Brandenberger H (1986) Positive-and negative-ion mass spectrometry of butyrophenones. J Chromatogr 382:135–145
Couper FJ, McIntyre IM, Drummer OH (1995) Detection of antidepressant and antipsychotic drugs in postmortem human scalp hair. J Forensic Sci 40:87–90
Nilsson LB (1988) Reversed-phase ion pair liquid chromatographic method for the determination of low concentrations of haloperidol in plasma. J Chromatogr 431:113–122
Hariharan M, Kindt EK, Van Noord T et al. (1989) An improved sensitive assay for simultaneous determination of plasma haloperidol and reduced haloperidol levels by liquid chromatography using a coulometric detector. Ther Drug Monit 11:701–707
Park KH, Lee MH, Lee MG (1991) Simultaneous determination of haloperidol and its metabolite, reduced haloperidol, in plasma, blood, urine and tissue homogenates by high-performance liquid chromatography. J Chromatogr 572:259–267
Eyles DE, Whiteford HA, Stedman TJ et al. (1992) Determination of haloperidol and reduced haloperidol in the plasma and blood of patients on depot haloperidol. Psychopharmacology 106:268–274
Fang J, Gorrod JW (1993) High-performance liquid chromatographic method for the detection and quantitation of haloperidol and seven of its metabolites in microsomal preparations. J Chromatogr B 614:267–273
Aravagiri M, Marder SR, Van Putten T et al. (1994) Simultaneous determination of plasma haloperidol and its metabolite reduced haloperidol by liquid chromatography with electrochemical detection: plasma levels in schizophrenic patients treated with oral or intramuscular depot haloperidol. J Chromatogr B 656:373–381
Igarashi K, Kasuya F, Abe T et al. (1995) Simultaneous determination of haloperidol and its neurotoxic metabolite in plasma and brain tissue from schizophrenic patients treated with haloperidol using HPLC and solid-phase extraction. Jpn J Forensic Toxicol 13:31–38
Pan L, Rosseel MT, Belpaire FM (1998) Comparison of two high-performance liquid chromatographic methods for monitoring plasma concentrations of haloperidol and reduced haloperidol. Ther Drug Monit 20:224–230
Walter S, Bauer S, Roots I et al. (1998) Quantification of the antipsychotics flupentixol and haloperidol in human serum by high-performance liquid chromatography with ultraviolet detection. J Chromatogr B 720:231–237
Igarashi K, Shigee Y, Kasuya F et al. (1997) Analysis of haloperidol and its neurotoxic pyridinium metabolite in biological samples by liquid chromatography/mass spectrometry. Jpn J Forensic Toxicol 15:44–54
Hoja H, Marquet P, Verneuil B et al. (1997) Determination of haloperidol and its reduced metabolite in human plasma by liquid chromatography-mass spectrometry with electrospray ionization. J Chromatogr B 688:275–280
Yamazaki F, Mori H (eds) (2000) Guide to Acute Poisonings by Medical Drugs. Van Medical, Tokyo, p 56 (in Japanese)
Uges DRA (1997) Blood level data. In: Brandenberger H, Maes RAA (eds) Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists. Walter de Gruyter, Berlin, pp 707–718
Uges DRA, Conemans JMH (2000) Antidepressants and antiphychotics. In: Bogusz MJ (ed) Handbook of Analytical Separations Vol.2, Forensic Science. Elsevier, Amsterdam, pp 229–257
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Igarashi, K. (2005). Butyrophenones. In: Drugs and Poisons in Humans. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27579-7_29
Download citation
DOI: https://doi.org/10.1007/3-540-27579-7_29
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-22277-4
Online ISBN: 978-3-540-27579-4
eBook Packages: MedicineMedicine (R0)