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References
Nichols DE (1986) Differences between the mechanism of action of MDMA, MBDB, and the classic hallucinogens. Identification of a new therapeutic class: entactogens. J Psychoactive Drugs 18:305–313
Nichols DE, Hoffman AJ, Oberlender RA et al. (1986) Derivatives of 1-(1,3-benzodioxol-5-yl)-2-butanamines: representatives of a novel therapeutic class. J Med Chem 29:2009–2015
Gouzoulis E, Steiger A, Ensslin HK et al. (1992) Sleep EEG effects of 3,4-methylenedioxyethylamphetamine (MDE, “Eve”) in healthy volunteers. Biol Psychiat 32:1108–1117
Katagi M, Tsutsumi H, Miki A et al. (2002) Analyses of clandestine tablets of amphetamines and their related designer drugs encountered in recent Japan. Jpn J Forensic Toxicol 20:303–319
Katagi M, Tsuchihashi H (2002) Update on clandestine amphetamines and their analogues recently seen in Japan. J Health Sci 48: 14–21
Helmlin H-J, Bracher K, Bourquin D et al. (1996) Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS. J Anal Toxicol 20:432–440
Ortuño J, Pizarro N, Farré M et al. (1999) Quantification of 3,4-methylenedioxymethamphetamine and its metabolites in plasma and urine by gas chromatography with nitrogen-phosphorus detection. J Chromatogr B 723:221–232
Kreth K-P, Kovar K-A, Schwab M et al. (2000) Identification of the human cytochromes P450 involved in the oxidative metabolism of “Ecstasy” related designer drugs. Biochem Pharmacol 59:1563–1571
Pizarro N, Ortuño J, Farré M et al. (2002) Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis. J Anal Toxicol 26:157–165
Clark CR, DeRuiter J, Noggle FT (1996) Chromatographic and mass spectrometric methods for the differentiation of N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine from regioisomeric derivatives. J Chromatogr Sci 34:230–237
Morgan PH, Beckett AH (1975) Synthesis of some N-oxygenated products of 3,4-methylenedioxyamphetamine and its N-alkyl derivatives. Tetrahedron 31:2595–2601
Zhao H, Brenneisen R, Scholer A et al. (2001) Profiles of urine samples taken from Ecstasy users at Rave parties: analysis by immunoassays, HPLC, and GC-MS. J Anal Toxicol 25:258–269
Letter EAD, Clauwaert KM, Lambert WE et al. (2002) Distribution study of 3,4-methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine in a fatal overdose. J Anal Toxicol 26:113–118
Stout PR, Horn CK, Klette KL (2002) Rapid simultaneou determination of amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine, 3,4-methylenedioxymethamphetamine, and 3,4-methylenedioxyethylamphe tamine in urine by solid-phase extraction and GC-MS: a method optimized for high-volume laboratories. J Anal Toxicol 26:253–261
Gill JR, Hayes JA, deSouza IS et al. (2002) Ecstasy (MDMA) deaths in New York City: a case series and review of the literature. J Forensic Sci 47:121–126
Kalant H (2001) The pharmacology and toxicology of “ecstasy” (MDMA) and related drugs. Can Med Assoc J 165:917–928
Kelly PA (2000) Does recreational ecstasy use cause long-term cognitive problem? West J Med 173:129–130
Mathias R (2000) “Ecstasy” damages the brain and impairs memory in humans. NIDA Notes 14
Weinmann W, Bohnert M (1998) Lethal monointoxication by overdosage of MDEA. Forensic Sci Int 91:91–101
Lora-Tamayo C, Tena T, Rodriguez A (1997) Amphetamine derivative related deaths. Forensic Sci Int 85: 149–157
Verebey K, Alrazi J, Jaffe JH (1988) The complications of “ecstasy” (MDMA). JAMA 259:1649–1650
Mas M, Farré, de la Torre R et al. (1999) Cardiovascular and meuroendocrine effects and pharmacokinetics of 3,4-methylenedioxymethamphetamine in humans. J Pharmacol Exp Ther 290:136–145
Tsuchihashi H, Nakajima K, Nishikawa M et al. (1989) Headspace gas chromatography of stimulants in urine by in-column trifluoroacetyl derivatization method. J Chromatogr 467:227–235
Tsuchihashi H, Nakajima K, Nishikawa M et al. (1991) Determination of methamphetamine and amphetamine in urine by headspace gas chromatography/mass spectrometry. Anal Sci 7:19–22
Shima N, Kamata T, Nishikawa M et al. Examination of the hydrolysis conditions of drug glucuronides in urine. In preparation
Ensslin HK, Maurer HH, Gouzoulis E et al. (1996) Metabolism of racemic 3,4-methylenedioxyethylamphetamine in humans. Isolation, identification, quantification, and synthesis of urinary metabolites. Drug Metab Dispos 24:813–820
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Katagi, M., Tsuchihashi, H. (2005). 3,4-Methylenedioxyamphetamines. In: Drugs and Poisons in Humans. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27579-7_25
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DOI: https://doi.org/10.1007/3-540-27579-7_25
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