Skip to main content
SpringerLink
Log in

Solide Tumoren

  • Chapter
Medizinische Therapie 2005|2006

  • 41 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

Literatur

  • Aapro MS (2001) Adjuvant therapy of primary breast cancer: a review of key findings from the 7th international conference, St. Gallen, February 2001. Oncologist 6: 376–85

    CAS  PubMed  Google Scholar 

  • Fisher ER, Land SR, Fisher B et al. (2004) Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: twelve-year observations concerning lobular carcinoma in situ. Cancer 100: 238–244

    Article  PubMed  Google Scholar 

  • Kennedy MJ, Abeloff MD (1993) Management of locally recurrent breast cancer. Cancer 71: 2395–2409

    CAS  PubMed  Google Scholar 

  • Mouridsen H, Gershanovich M, Sun Y et al. (2003) Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group. J Clin Oncol 21: 2101–2109

    Article  CAS  PubMed  Google Scholar 

  • NIH, National Institutes of Health (2000) Consensus Development Conference Statement — adjuvant therapy for breast cancer.

    Google Scholar 

  • Possinger K, Schmoll HJ, Höffken K, Große Y (1999) Mammakarzinom. In: Schmoll HJ, Höffken K, Possinger K (Hrsg) Kompendium Internistische Onkologie, vol 2. Springer, Berlin Heidelberg New York Tokyo, pp 1253–1342

    Google Scholar 

  • Silverstein MJ, Buchanan C (2003) Ductal carcinoma in situ: USC/Van Nuys Prognostic Index and the impact of margin status. Breast 12: 457–471

    Article  PubMed  Google Scholar 

  • Singletary SE, Allred C, Ashley P et al. (2002) Revision of the American Joint Committee on Cancer staging system for breast cancer. J Clin Oncol 20: 3628–3636

    Article  PubMed  Google Scholar 

Literatur

  • Altwein JE (1997) Prostatakarzinom. In: Rübben H (Hrsg) Uroonkologie, 2. Aufl. Springer, Berlin Heidelberg New York Tokyo, S 233–293

    Google Scholar 

  • Carter BS, Bova GS, Beaty TH, Steinberg GD, Childs B, Isaacs WB, Walsh PC (1993) Heriditary prostate cancer: epidemiologic and clinical features. J Urol 150(3): 797–802

    CAS  PubMed  Google Scholar 

  • Hölzel D (1991) Epidemiologie des Prostatakarzinoms. Fortschr Med 109(26): 521–525

    PubMed  Google Scholar 

  • Mostofi FK, Sesterhenn J, Sobin LH (1980) Histologic typing of prostate tumors., WHO, Genua, No. 22

    Google Scholar 

  • Otto T., Betz D., Otto J.(2004) Urologische Tumore. Akt. Onkol. 124: 154–160

    Google Scholar 

  • Wirth M, Otto T, Rübben H (1998) Prostatakarzinom. Leitlinien der Deutschen Gesellschaft für Urologie. DGU-Mitteilungen 1998

    Google Scholar 

  • Wirth M. (2001) Terapie des lokal begrenzten Prostatakarzinom. In: Rübben H (Hrsgb) Uroonkologie. 3.Aufl. Springer, Berlin Heidelberg New York Tokyo, S 287–393

    Google Scholar 

Literatur

  • Weißbach L, Albers P (2001) Hodentumoren. In: Rübben H (Hrsg) Uroonko-logie, 3. Aufl. Springer, Berlin Heidelberg New York Tokio, S 361–467

    Google Scholar 

  • Krege S, Schmoll H-J, Souchon R (2001) Interdisziplinärer Konsensus zur Diagnostik und Therapie von Hodentumoren. Ergebnisse einer Update-Konferenz auf Grundlage evidenzbasierter Medizin (EBM). Urol A 40: 137–147

    CAS  Google Scholar 

  • Schmoll HJ, Souchon R, Krege S (2004) European consensus on diagnosis and treatment of germ cell cancer: a report of the European Germ Cell Cancer Consensus Group (EGCCCG) Annals of Oncology 15: 1377–1399

    CAS  PubMed  Google Scholar 

Literatur

  • Castilla LH, Couch SJ, Erdos MR et al. (1994) Mutations in the BRCA1-Gene in families with early-onset breast and ovarian cancer. Mature Genet 8: 387–391

    CAS  Google Scholar 

  • Deutsche Krebsgesellschaft (1998/2000/2001) Qualitätssicherung in der Onkologie. Diagnose und Therapie maligner Erkrankungen. Kurzgefasste Interdisziplinäre Leitlinien 2000, S 301 ff

    Google Scholar 

  • Emons G, Ortmann O, Pahwa GS (1992) LH-RH agonists in the treatment of ovarian cancer. In: Höffken K (ed) Peptides in oncology I. LH-RH agonists and antagonists. Zuckschwerdt, München Bern Wien New York, p 55

    Google Scholar 

  • Grab D, Flock F, Stöhr I (2000) Classification or asymptomatic adnexal masses by ultrasound, magnetic resonance imaging, and positron emis-sion tomography. Gynecol Oncol 77: 454–459

    Article  CAS  PubMed  Google Scholar 

  • Kuhn W (2001) Maligne Ovarialtumoren, 6. Aufl. W. Zuckschwerdt, München, S 24–31

    Google Scholar 

  • Kuhn W, Rutke S, Späthe K et al. (2001) Neo-adjuvant chemotherapy followed by tumor-debulking prolongs survival for patients with poor prognosis in ovarian cancer FIGO III c. Cancer: in press

    Google Scholar 

  • Markman M, Rothman R, Hakes T, Reichman B, Hoskins W, Rubin S, Jones W, Almadrones L, Lewis JL Jr (1991) Second-line platinum therapy in patients with ovarian cancer previously treated with cisplatin. J Clin Oncol 9: 389–393

    CAS  PubMed  Google Scholar 

  • National Cancer Institute (1998) Screening for ovarian cancer. Tumorzentrum München

    Google Scholar 

  • Rutke S, Späthe K, Schmalfeldt B, Graeff H, Kuhn W (2000) Primäre Chemotherapie beim fortgeschrittenen Ovarialkarzinom: Alternative zum radikalen operativen Tumordebulking? In: Schmid L, Wilmanns (eds) Praktische Onkologie. Akt Onkol Bd 109, Zuckschwerdt, München Bern Wien New York, pp 141–147

    Google Scholar 

  • Schelling, Kuhn, Gnirs et al. (1998) Kombination von Sonographie und farbkodierter Dopplersonographie zur Dignitätsbeurteilung von Ovarialtumoren. Geburtsh Frauenheilk 58: 382–387

    Google Scholar 

  • Scully RE, Sobin LH (1999) World Health Organisation (WHO). International histological classification of tumours. Histological typing of ovarian tumours. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  • Scully RE, Young RH, Clement Ph B (1998) Atlas of tumor pathology: Tumors of ovary, maldeveloped gonads, fallopian tube, and broad ligament. AFIP, Washington, D.C.

    Google Scholar 

  • Sobin LH, Wittekind C (1997) UICC, TNM Classification of malignant tumors, 5. Aufl. Wiley-Liss, New York

    Google Scholar 

  • Uzolds RS, Rubin SC, Thomas G, Robbuy S (1997) Epithelial ovarian cancer. In: Hoskins WJ, Perez CA, Young RC (eds) Principles and practice of gynecologic oncology, 2nd edn. Lippencott Raven, Philadelphia, p 919

    Google Scholar 

Literatur

  • ACOG, Commitee Opinion (1993) Estrogen replacement therapy and endometrial cancer. p 126

    Google Scholar 

  • Alberts DS, Mason-Liddil N (1989) The role of cisplatin in the management of advanced squamous cell cancer of the cervix. Semin Oncol 16(Suppl 6): 66–78

    CAS  PubMed  Google Scholar 

  • Atzinger A (1996) Bestrahlung beim Zervixkarzinom nach radikaler Operation: Welches Zielvolumen? Ist prophylaktische Bestrahlung der Paraaortalregion effektiv? Strahlenther Onkol 172: 229–230

    CAS  PubMed  Google Scholar 

  • AWMF online (2001) Therapie der Adipositas. Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften. Leitlinien der Deutschen Adipositas-Gesellschaft

    Google Scholar 

  • Barakat RR, Park RC, Grigsby PW, Muss HD, Norris HJ (1997) Corpus: epi-thelial tumors. In: Hoskins et al. (eds) Principles and practice of gynecologic oncology. Lippincott Williams & Wilkins, Philadelphia, pp 859 ff

    Google Scholar 

  • Berman ML, Ballon SC, Lagasse LD, Watring WG (1980) Prognosis and treatment of endometrial cancer. Am J Obstet Gynecol 136: 679–688

    CAS  PubMed  Google Scholar 

  • Bischoff J (2000) Hormon-und Chemotherapie in der Rezidiv-und Palliativ-situation. In: Tumorzentrum München: Manual Malignome des Corpus uteri. Zuckschwerdt, München, S 52–56

    Google Scholar 

  • Buckley SL, Tritz DM, Van Le L et al. (1996) Lymph node metastases and pro-gnosis in patients with stage IA2 cervical cancer. Gynec Oncol 63: 4–9

    CAS  Google Scholar 

  • Burghardt E, Girardi F, Lahousen M et al. (1991) Microinvasive carcinoma of the uterine cervix (International Federation of Gynecology and Obstetrics Stage OA). Cancer 67: 1037

    CAS  PubMed  Google Scholar 

  • Burghardt E, Östör A, Fox H (1997) Editorial: The new FIGO definition of cervical cancer stage I a: a critique. Gynecol Oncol 65: 1–5

    Article  CAS  PubMed  Google Scholar 

  • Burghardt E, Webb MJ, Monaghan JM, Kindermann G (1993) Surgical gynecologic oncology. Thieme, Stuttgart New York

    Google Scholar 

  • Creasman WT (1995) New gynecologic cancer staging. Gynec Oncol 58: 157–158

    CAS  Google Scholar 

  • Delgado G, Bundy BN, Fowler WE et al. (1989) A prospective surgical pathological study of stage I squamous carcinoma of cervix: a Gynecologic Oncology Group study. Gynecol Oncol 35: 314

    Article  CAS  PubMed  Google Scholar 

  • Deutsche Krebsgesellschaft (2000) B22 Endometriumkarzinom. In: Qualitätssicherung in der Onkologie — Diagnose und Therapie maligner Erkrankungen. Kurzgefasste interdisziplinäre Leitlinien 2000. Zuckschwerdt, München, S 287 ff

    Google Scholar 

  • DiSaia PJ, Creasman WT (1997) Sarcoma of the uterus. In: Clinical gynecologic oncology, 5th ed. Mosby, St. Louis Baltimore Boston, pp 169–179

    Google Scholar 

  • Geisthövel F (1998) Obesity in female life — from molecular to clinical aspects. Zentralbl Gynakol 120(5): 223–234

    PubMed  Google Scholar 

  • Gershenson DM, Kavanagh JJ, Copeland LJ, Edwards CL, Stringer CA, Wharton JT (1987) Cisplatin therapy for disseminated mixed mesodermal sarcoma of the uterus. J Clin Oncol 5(4): 618–621

    CAS  PubMed  Google Scholar 

  • Glassburn JR (1981) Carcinoma of the endometrium. Cancer 48: 575–581

    CAS  PubMed  Google Scholar 

  • Gusberg SB (1976) The evolution of modern treatment of corpus cancer. Cancer 38: 603–609

    CAS  PubMed  Google Scholar 

  • Hatch KD, Gelder MS, Soong SJ, Baker VV, Shingleton HM (1990) Pelvic exenteration with low rectal anastomosis: survival, complications, and prognostic factors. Gynecol Oncol 38: 462–467

    Article  CAS  PubMed  Google Scholar 

  • Hoffmann W, Hirnle P, Clemens M et al. (1995) 13cis-retinoic acid in combination with interferon-alpha and concomitant irradiation in squamous cell carcinomas — toxicity and feasibility. Onkologie 18: 568–571

    Google Scholar 

  • Hoffmann W, Schiebe M, Clemens M, Souchon R, Hirnle P, Adamietz I, Bambert M (1997) 13cis-retinoic acid and interferon-alpha ± irradiation in squamous cell carcinomas. Int J Cancer 70: 475–477

    Article  CAS  PubMed  Google Scholar 

  • IARC Monograph (1995) IARC monographs on the evaluation of carcinogenic risks to humans. Human papillomaviruses. IARC, Lyon, p 64

    Google Scholar 

  • Käser O (1983) Operative Möglichkeiten bei der Therapie des Endometriumkarzinoms. Gynäkologe 16: 99–103

    PubMed  Google Scholar 

  • Kreienberg R (1998) Fortgeschrittene Stadien des invasiven Zervixkarzinoms — Operative Therapie. Onkologe 2: 142–152

    Google Scholar 

  • Kumar L, Grover R, Pokharel YH, Chander S, Kumar S, Singh R, Rath GK, Kochupillai V (1998) Neoadjuvant chemotherapy in locally advanced cervical cancer: two randomised studies. Aust N Z J Med 28: 387–390

    CAS  PubMed  Google Scholar 

  • Lacava JA, Leone BA, Machiavelli M et al. (1997) Vinorelbine as neoadjuvant chemotherapy in advanced cervical carcinoma. J Clin Oncol 15: 604–609

    CAS  PubMed  Google Scholar 

  • Larson B, Silfverswärd C, Nilsson B, Petterson F (1990) Mixed Müllerian tumours of the uterus — prognostic factors: a clinical and histopathologic study of 147 cases. Radiother Oncol 17: 123–132

    Article  CAS  PubMed  Google Scholar 

  • Lawton F (1997) The management of endometrial cancer. Br J Obstet Gynaecol 104: 127–134

    CAS  PubMed  Google Scholar 

  • Leminen A, Forss M, Lehtovirta P (1995) Endometrial adenocarcinoma with clinical evidence of cervical involvement: accuracy of diagnostic procedures, clinical course, and prognostic factors. Acta Obstet Gynecol Scand 74: 61–66

    CAS  PubMed  Google Scholar 

  • Limper A, Rauthe G (2000) Nachsorge. In: Tumorzentrum München: Manual Malignome des Corpus uteri. Zuckschwerdt, München, S 57–69

    Google Scholar 

  • Lindner H, Likas P, Willgeroth F, Würschmidt F (2000) Radioonkologische Behandlung. In: Tumorzentrum München: Manual Malignome des Corpus uteri. Zuckschwerdt, München, S 39–46

    Google Scholar 

  • Lippman SM, Kavanagh JJ, Paredes-Espinoza M et al. (1992) 13-cis-retinoic acid plus interferon alpha-2a: highly active systemic therapy for squa-mous cell carcinoma of the cervix. J Natl Cancer Inst 84: 241–245

    CAS  PubMed  Google Scholar 

  • Lotocki RJ, Copeland LJ, De Petrillo AD, Muirhead W (1983) Stage I endo-metrial carcinoma: treatment results in 835 patients. Am J Obstet Gyne-col 146: 141–145

    CAS  Google Scholar 

  • Major FJ, Blessing JA, Silverberg SG, Morrow CP, Creasman WT, Currie JL (1993) Prognostic factors in early stage uterine sarcoma — a GOG study. Cancer 71: 1702–1706

    CAS  PubMed  Google Scholar 

  • Manchul L, Pintilie M, Lefebvre P, Fyles A, Kirkbride P, Levin W, Rawlings G (1994) Uterine sarcomas: prognostic factors and the role of radiation therapy. Int J Radiat Oncol Biol Phys 30(Suppl 1): 284

    Google Scholar 

  • Möbus V, Kreienberg R (1998) Systemische Therapie des Zervixkarzinoms. Onkologe 4: 167–173

    Google Scholar 

  • Morris M, Eifel PJ, Lu J et al. (1999) Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer. N Engl J Med 340: 1137–43

    Article  CAS  PubMed  Google Scholar 

  • National Cancer Institute (1999) Concurrent chemoradiation for cervical cancer. Clinical announcement, Washington, D.C.

    Google Scholar 

  • Oberlechner E (2000) Adjuvante medikamentöse Therapie. In: Tumorzentrum München: Manual Malignome des Corpus uteri. Zuckschwerdt, München, S 47–51

    Google Scholar 

  • Park RC, Thigpen JT (1993) Chemotherapy in advanced and recurrent cervical cancer. A review. Cancer 71(Suppl): 1446–1450

    CAS  PubMed  Google Scholar 

  • Pecorelli S (1998) FIGO Annual report on the results of treatment in gynaecological cancer, 23rd ed. J Epidemiol Biostat 3: 1–168

    Google Scholar 

  • Peters III WA, Liu PY, Barrett II RJ et al. (2000) Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J Clin Oncol 18:1606–1613

    CAS  PubMed  Google Scholar 

  • Pettersson F (1994) Annual report on the results of treatment in gyneco-logical cancer. Radiumhemmet, Stockholm

    Google Scholar 

  • Potter ME, Hatch KD, Potter MY, Shingleton HM, Baker VV (1989) Factors affecting the response of recurrent squamous cell carcinoma of the cervix to cisplatin. Cancer 63: 1283–1286

    CAS  PubMed  Google Scholar 

  • Rakar S, Kovacic J (1990) Prognostic factors in endometrial cancer. Eur J Gynaec Oncol 11: 233–235

    CAS  Google Scholar 

  • Sardi J, Sananes C, Giaroli AR et al. (1993) Results of a prospective randomized trial with neoadjuvant chemotherapy in stage IB, bulky, squamous carcinoma of the cervix. Gynecol Oncol 49: 156–165

    Article  CAS  PubMed  Google Scholar 

  • Scully RE, Bonfiglio T, Kurman RJ, Silverberg S, Williamson EJ (1994) World Health Organization international histological classification of tumors, histological typing of female genital tract tumors, 2nd ed. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  • Shingleton HM, Thompson JD (1997) Cancer of the cervix. In: Rock JA, Thompson JD (eds) Te Linde’s operative gynecology. Lippincott-Raven, Philadelphia New York, pp 1413–1499

    Google Scholar 

  • Sutton GP, Blessing JA, Homesley HD, McGuire WP, Adcock L (1994) Phase II study of ifosfamide and mesna in refractory adenocarcinoma of the endometrium: a Gynecologic Oncology Group study. Cancer 73: 1453–1455

    CAS  PubMed  Google Scholar 

  • Thomas GM (1999) Improved treatment for cervical cancer — concurrent chemotherapy and radiotherapy. Editorial. N Engl J Med 340: 1198–1200

    Article  CAS  PubMed  Google Scholar 

  • Thomas GM (2000) Concurrent chemotherapy and radiation for locally advanced cervical cancer: the new standard of care. Semin Radiat Oncol 10(1): 44–50

    CAS  PubMed  Google Scholar 

  • Toki N, Tsukamoto N, Kaku T, Toh N, Saito T, Kamura T, Matsukuma K, Nakano H (1991) Microscopic ovarian metastasis of the uterine cervical cancer. Gynecol Oncol 41: 46–51

    Article  CAS  PubMed  Google Scholar 

  • Wulf J, Flentje M (1998) Strahlentherapie des Zervixkarzinoms. Onkologe 4: 153–166

    Article  Google Scholar 

Literatur

  • Albeida SM (1998) Gene therapy for lung cancer and mesothelioma. Chest 111: 144S–149S

    Google Scholar 

  • Antman KH, Pass HI, Schiff PB (2001) Management of Mesothelioma. In: De Vita VT Jr (ed) Cancer. Principles and Practice of Oncology, 6th edn. Section 2. Lippincott, Williams and Wilkins, Philadelphia, pp 1943–1964

    Google Scholar 

  • Baas P, Murrer L, Zoetmulder FA et al. (1997) Photodynamic therapy as adjuvant therapy in surgically resected pleural malignancies. Br J Cancer 76: 819–826

    CAS  PubMed  Google Scholar 

  • Byrne MJ, Davidson JA, Musk AW et al. (1999) Cisplatin and Gemcitabine treatment for malignant mesothelioma. A phase-II study. J Clin Oncol 17: 25

    CAS  PubMed  Google Scholar 

  • Chahinian GA, Pass HI (2000) Malignant mesothelioma. In: Bast RC, Kufe DW, Pollock RE et al. (eds) Cancer Medicine, 5th edn. B.C. Decker, News York, pp 1293–1312

    Google Scholar 

  • Eberhardt W, Dienemann H, Stüben G (2002) Malignes Mesotheliom. In: Seeber S, Schütte J (eds) Therapiekonzepte Onkologie. Springer, Berlin Heidelberg New York Tokyo (im Druck)

    Google Scholar 

  • Giaccone G, Baas P (1999) Mesotheliomas. In: Raghavan D, Brecher ML, Johnson DH et al. (eds) Textbook of uncommon cancer, 2nd edition, pp 523–535. Wiley, Chichester New York Weinheim Brisbane Singapore Toronto

    Google Scholar 

  • Peto J, Decarli A, La Vecchia C et al. (1999) The European mesothelioma epidemic. Br J Cancer 79: 666–672

    Article  CAS  PubMed  Google Scholar 

  • Rusch VW (1995) A proposed new international TNM staging system for malignant pleural mesothelioma. Chest 108: 1122

    CAS  PubMed  Google Scholar 

  • Sugarbaker DJ, Garcia JP, Richards et al. 1996) Extrapleural pneumonectomy in the multimodality therapy of malignant pleural mesothelioma. Results in 120 consecutive patients. Ann Surgery 224: 288

    CAS  Google Scholar 

  • Testa JR, Pass HI, Carbone M (2001) Molecular biology of mesothelioma. In: De Vita (ed) Cancer. Principles and Practice of Oncology. 6th edition. Section 2. Lippincott, Williams and Wilkins, Philadelphia, pp 1937–1942

    Google Scholar 

  • Van Meerbeeck J, Manegold C, R. Gaafar, et al. (2004) A randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: An intergroup study of the EORTC Lung Cancer Group and NCIC. J Clin Oncol 22 (July 15 Supplement): 7021

    Google Scholar 

  • Vogelzang NJ, Rusthoven JJ, Symanowski J, et al. (2003) Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J Clin Oncol 21: 2636–2644

    Article  CAS  PubMed  Google Scholar 

  • Weder W, Kestenholz P, Taverna C, et al. (2004) Neoadjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma. J Clin Oncol 22: 3451–3457

    Article  CAS  PubMed  Google Scholar 

Literatur

  • Blay JY, Bouhour D, Ray-Coquard I, Dumontet C, Philip T, Biron P (2000) High-dose chemotherapy with autologous hematopoietic stem-cell transplantation for advanced soft-tissue sarcoma in adults. J Clin Oncol 3643–3650

    Google Scholar 

  • Coindre JM, Terrier P, Binh Bui N, Bonichon F, Collin F, Le Doussal V et al. (1996) Prognostic factors in adult patients with locally controlled soft tissue sarcoma: a study of 546 patients from the French Federation of Cancer Centers Sarcoma Group. J Clin Oncol 14: 869–877

    CAS  PubMed  Google Scholar 

  • Graadt van Roggen JF, van Velthuysen MLF, Hogendoorn PCW (2001) The histopathological differential diagnosis of gastrointestinal stromal tumours. J Clin Pathol 54: 96–103

    CAS  PubMed  Google Scholar 

  • Guillou L, Coindre JM, Bonichon F, Binh Bui N, Terrier P, Collin F, et al. (1997) Comparative study of the National Cancer Institute and French Federation of Cancer Centers Sarcoma Group Grading Systems in a population of 410 adult patients with soft tissue sarcoma. J Clin Oncol 1997; 15: 350–362

    CAS  PubMed  Google Scholar 

  • Heslin MJ, Lewis JJ, Nadler E, Newman E, Woodruff JM, Casper ES et al. (1997) Prognostic factors associated with long-term survival for retroperitoneal sarcoma: implications for management. J Clin Oncol 15: 2832–2839

    CAS  PubMed  Google Scholar 

  • Issels R, Abdel-Rahman S, Wendtner CM, Falk MH, Kurze V, Sauer H et al. (2001) Neoadjuvant chemotherapy combined with regional hyper-thermie (RHT) for locally advanced primary or recurrent high-risk adult soft-tissue sarcomas (STS) of adults: long-term results of a phase II study. Eur J Cancer 37: 1599–1608

    Article  CAS  PubMed  Google Scholar 

  • Issels R (2004) Empfehlungen zur Diagnostik, Therapie und Nachsorge. Knochentumoren/Weichteilsarkome, 4. Aufl. Tumorzentrum München (Hrsg.) W. Zuckerschwerdt Verlag München

    Google Scholar 

  • Koscielniak E, Harms D, Henze G, Jürgens H, Gadner H, Herbst M et al. (1999) Results of treatment for soft tissue sarcoma in childhood and adolescence: A final report of the German Cooperative Soft Tissue Sarcoma Group CWS-86. J Clin Oncol 17: 3706–3719

    CAS  PubMed  Google Scholar 

  • Trovik CS, Bauer HCF, Alvegard TA, Anderson H, Blomqvist C, Berlin Ö et al. (2000) Surgical margins, local recurrence and metastasis in soft tissue sarcomas: 559 surgically-treated patients from the Scandinavian Sarcoma Group Register. Eur J Cancer 36: 710–716

    Article  CAS  PubMed  Google Scholar 

  • Wendtner CM, Abdel-Rahman S, Krych M, Baumert J, Lindner LH et al. (2002) Response to neoadjuvant chemotherapy combined with regional hyperthermia predicts long-term survival for adult patients with retroperitoneal and visceral high-risk soft tissue sarcomas. J Clin Oncol 20: 3156–3164

    Article  CAS  PubMed  Google Scholar 

  • Yang JC, Chang AE, Baker AR, Sindelar WF, Danforth DN, Topalian SL et al. (1998) Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity. J Clin Oncol 16: 197–203

    CAS  PubMed  Google Scholar 

Literatur

  • Ang KK, Trotti A, Brown BW et al. (2001) Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 51: 571–578

    Article  CAS  PubMed  Google Scholar 

  • Awwad HK, Lotayef M, Shouman T et al. (2002) Accelerated hyper-fractio-nation (AHF) compared to conventional fractionation (CF) in the postoperative radiotherapy of locally advanced head and neck cancer: influence of proliferation. Br J Cander 86: 517–523

    CAS  Google Scholar 

  • Bernier J, Domenge C, Ozsahin M et al. (2004) Postoperative irridiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 350: 1945–1952

    Article  CAS  PubMed  Google Scholar 

  • Browman GP, Hodson DI, Mackenzie RJ et al. (2001) Choosing a concomitant chemotherapy and radiotherapy regimen for sqamous cell head and neck cancer: a systematic review of the published literature with a subgroup analysis. Head Neck 23: 579–589

    Article  CAS  PubMed  Google Scholar 

  • Budach V, Budach W (2001) Sequentielle und simultane Radiochemotherapie bei lokal fortgeschrittenen Kopf-Hals-Tumoren. Onkologe 5: 533–549

    Google Scholar 

  • Cooper JS, Pajak TF, Forastiere AA et al. (2004) Postoperative concurrent radiotherapy and chemotherapy in high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 350: 1937–1944

    Article  PubMed  Google Scholar 

  • El-Sayed S, Nelson N (1996) Adjuvant and adjunctive chemotherapy in the management of squamous cell carcinoma of the head and neck region: A meta-analysis of prospective and randomized trials. J Clin Oncol 14: 838–847

    CAS  PubMed  Google Scholar 

  • Ganly I, Kaye SB (2000) Recurrent squamous-cell carcinoma of the head and neck: overview of current and future prospects. Ann Oncol 11: 11–26

    Article  CAS  PubMed  Google Scholar 

  • Jacobs C, Lyman G, Velez-Garcia E (1992) A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combina-tion for advanced squamous cell carcinoma of the head and neck. J Clin Oncol 10: 257–263

    CAS  PubMed  Google Scholar 

  • List MA, Haraf D, Stracks J, Stenson B, Brockstein M, Kies F, Rosen E, Vokes EE (2000) Quality of life (QOL) performance in head and neck cancer (HNC): comparison between paclitaxel-based (P-CT/XRT) and cisplatin-based (C-CT/XRT) concomitant chemoradiotherapy regimens. Proc Am Soc Clin Oncol 19: 412a (A1625)

    Google Scholar 

  • Pignon JP, Bourhis J, Domenge C et al. (2000) Chemotherapy added to local treatment for head and neck squamous cell carcinoma: three meta-analyses of updated individual data. MACH-NC collaborative group. Lancet 355: 949–955

    CAS  PubMed  Google Scholar 

  • Posner MR, Colevas D (2000) The role of induction chemotherapy in the curative treatment of squamous cell cancer of the head and neck. Sem Oncol 27: 13–24

    CAS  Google Scholar 

  • Vokes EE, Athanasiadis I (1996) Chemotherapy for squamous cell carcinoma of head and neck: the future is now. Ann Oncol 7: 15–29

    CAS  PubMed  Google Scholar 

  • Wendt TG, Grabenhauer GG, Rödel CM (1998) Simultaneous radiochemo-therapy versus radiotherapy alone in advanced head and neck cancer: a randomized multicenter study. J Clin Oncol 16: 1318–1324

    CAS  PubMed  Google Scholar 

  • Wust P, Stahl H, Dieckmann K (1996) Local hyperthermia of N2/N3 cervical lymph node metastases: correlation of technical/thermal parameters and response. Int J Radiat Oncol Biol Phys 34(3): 635–646

    Article  CAS  PubMed  Google Scholar 

Literatur

  • Bokemeyer C (1999) Tumormetastasen bei unbekanntem Primärtumor. In: Thiemes Innere Medizin. Thieme, Stuttgart New York, S 1022–1027

    Google Scholar 

  • Bugat R, Bataillard A, Lesimple T et al. (2002) Summary of the standards, options and recommendations for the management of patients with carcinoma of unknown primary site. Br J Cancer 89: 59–66

    Google Scholar 

  • Culine S, Kramar A, Saghatchian M et al.(2002) Development and validation of a prognostic model to predict the length of survival in patients with carcinomas of an unknown primary site. J Clin Oncol 24: 4679–4683

    Google Scholar 

  • Culine S, Lortholary A, Voigt JJ et al. (2003) Cisplatin in compination with either gemcitabine of Irinotecan in carcinomas of unknown primary site: results of a randomized phase II study — trial for the French study group on carcinomas of unknown primary (GEFCAPI 01). J Clin Oncol 18: 3479–3482

    Google Scholar 

  • Delgado-Bolton RC, Fernandez-Perez C, Gonzalez-Mate A, Carreras J (2003) Meta-analysis of the performance of 18F-FDG PET in primary tumor detection in unknown primary tumors. J Nucl Med 44: 1301–1314

    PubMed  Google Scholar 

  • Hainsworth JD, Erland JB, Kalman LA, Schreeder MT, Greco FA (1997) Carcinoma of unknown primary site: treatment with 1-hour paclitaxel, carboplatin, and extended-schedule etoposide. J Clin Oncol 15: 2385–2393

    CAS  PubMed  Google Scholar 

  • Hess KR, Abbruzzese MC, Lenzi R, Raber MN, Abbruzzese JL (1999) Classification and regression tree analysis of 1000 consecutive patients with unknown primary carcinoma. Clin Cancer Res 5: 3403–3410

    CAS  PubMed  Google Scholar 

  • Hübner G, Wildfang I, Schmoll HJ (1999) Metastasen bei unbekanntem Primärtumor — CUP-Syndrom. In: Schmoll HJ, Höffken K, Possinger K (Hrsg) Kompendium Internistische Onkologie, 3. Aufl. Springer, Berlin Heidelberg New York Tokyo, S 2137–2182

    Google Scholar 

  • Pavlidis N, Briasoulis E, Hainsworth J, Greco FA (2003) Diagnostic and therapeutic management of cancer of an unknown primary. Eur J Cancer 39: 1990–2005

    Article  CAS  PubMed  Google Scholar 

  • Van de Wouw AJ, Jansen RL, Speel EJM, Hillen HFP (2003) The unknown biology of the unknown primary tumour: a literature review. Ann Oncol 14: 191–196

    PubMed  Google Scholar 

  • Varadhachary GR, Abbruzzese JL, Lenzi R (2004) Diagnostic strategies for unknown primary cancer. Cancer 100: 1776–1785

    Article  CAS  PubMed  Google Scholar 

Download references

Authors
  1. Kurt Possinger
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Anne C. Regierer
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Thomas Otto
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Herbert Rübben
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Susanne Krege
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Volker Hanf
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Rolf Kreienberg
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Wilfried Eberhardt
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Rolf D. Issels
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Hanno Riess
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Carsten Bokemeyer
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Klinik und Poliklinik für Innere Medizin I, Klinikum der Universität Regensburg, D-93042, Regensburg

    Jürgen Schölmerich

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Heidelberg

About this chapter

Cite this chapter

Possinger, K. et al. (2005). Solide Tumoren. In: Schölmerich, J., et al. Medizinische Therapie 2005|2006. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27385-9_21

Download citation

  • DOI: https://doi.org/10.1007/3-540-27385-9_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-21226-3

  • Online ISBN: 978-3-540-27385-1

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation