Skip to main content
SpringerLink
Log in

Tumorbiologie und moderne Labordiagnostik

  • Chapter
Pleuramesotheliom

  • 277 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 9.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Aitman TJ (2001) DNA microarrays in medical practice. Br Med J 323: 611–615

    CAS  Google Scholar 

  • Balaña C, Ramirez JL, Taron M et al. (2003) MGMT methylation in serum and tumor DNA predicts response to BCNU but not to temozolamide plus cisplatin in glioblastoma multiform. Clin Cancer Res 9(4): 1461–1468

    PubMed  Google Scholar 

  • Bustin SA (2000) Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol 25: 169–193

    Article  CAS  PubMed  Google Scholar 

  • Chen X, Sullivan PF (2003) Single nucleotide polymorphism genotyping: biochemistry, protocol, cost and throughput. Pharmocol J 3: 77–96

    Google Scholar 

  • Dabholkar M, Vionnet J, Bostick-Bruton F et al (1994) Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy. J Clin Invest 94: 703–708

    CAS  PubMed  Google Scholar 

  • Duggan DJ, Bittner M, Chen Y et al (1999) Expression profiling using cDNA microarrays. Nat Genet 21(Suppl 1): 10–14

    CAS  PubMed  Google Scholar 

  • Esteller M, Garcia-Foncillas J, Andion et al. (2000) Inactivation of the DNA repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343: 1350–1354

    Article  CAS  PubMed  Google Scholar 

  • Ford BN, Ruttan CC, Kyle VL et al. (2000) Identification of single nucleotide polymorphisms in human DNA repair genes. Carcinogenesis 21: 1977–1981

    CAS  PubMed  Google Scholar 

  • Herman JG, Baylin SB (2003) Gene silencing in cancer in association with promoter hypermethylation. New Engl J Med 20: 2042–2054

    Google Scholar 

  • Hu G, Modrek B, Stensland HMFR et al. (2002) Efficient dis-covery of single-nucleotide polymorphisms in coding regions of human genes. Pharmacogenomics J 2: 236–242

    Article  CAS  PubMed  Google Scholar 

  • Isla D, Sarries C, Rosell R et al. (2004) Single nucleotide polymorphisms and outcome in docetaxel/cisplatin-treated advanced non-small-cell lung cancer. Ann Oncol 15:1194–1203

    Article  CAS  PubMed  Google Scholar 

  • Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3: 415–428

    Article  CAS  PubMed  Google Scholar 

  • Krug L Azzoli CG, Kris MG, et al (2003) 10-Propargyl-10-deazaaminopterin: an antifolate with activity in patients with previously treated non-small cell lung cancer. Clin Cancer Res 9: 2072–2078

    CAS  PubMed  Google Scholar 

  • Lander ES (1999) Array as a hope. Nat Genet 21(Suppl 1): 3–4

    CAS  PubMed  Google Scholar 

  • Lehmann U, Kreipe H (2001) Real Time PCR analysis of DNA and RNA extracted from formalin-fixed and paraffin-embedded bio-psies. Methods 25: 409–418

    Article  CAS  PubMed  Google Scholar 

  • Li Q, Yu JJ, Mu C. et al. (2000) Association between the level of ERCC1 expression and the repair of cisplatin-induced DNA damage in human ovarian cancer cells. Anticancer Res 20: 645–652

    CAS  PubMed  Google Scholar 

  • Lord RVN, Brabender J, Gandara D et al. (2002) Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small-cell lung cancer. Clin Cancer Res 8: 2286–2291

    CAS  PubMed  Google Scholar 

  • Metzger R, Leichman G, Danenberg KD et al. (1998) ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy. J Clin Oncol 16: 309–316

    CAS  PubMed  Google Scholar 

  • Ntzani E, Ioannidis JPA (2003) Predictive ability of microarrays for cancer outcomes and correlates: an empirical assess-ment. The Lancet 362: 1439–1444

    Article  CAS  Google Scholar 

  • Ramírez JL, Sàrries C, López de Castro P et al. (2003) Methylation patterns and k-ras mutations in tumors and paired serum of resected NSCLC patients. Cancer Letters 193(2): 207–216

    PubMed  Google Scholar 

  • Ring HZ, Kroetz DL (2002) Candidate gene approach for pharmacogenomic studies. Pharmacogenomics 3(1): 47–56

    Article  CAS  PubMed  Google Scholar 

  • Roden DM, George AL (2002) The genetic basis of variability in drug responses. Nature Rev 1: 37–44

    CAS  Google Scholar 

  • Rosell R, Crino L, Danenberg K et al. (2003a) Targeted therapy in combination with gemcitabine in NSCLC. Sem Oncol 30(4): 19–25

    CAS  Google Scholar 

  • Rosell R, Scagliotti G, Danenberg KD et al. (2003b) Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer. Oncogene 22: 3548–3553

    Article  CAS  PubMed  Google Scholar 

  • Rosell R, Danenberg KD, Alberola V et al. (2004) Ribonucleotide reductase mRNA expression and survival in gemcitabine/ cisplatin-treated advanced non-small-cell lung cancer patients. Clin Cancer Res 15: 1318–1325

    Google Scholar 

  • Sarries C, Haura EB, Roig B et al. (2002) Pharmacogenomic strategies for developing customized chemotherapy in nonsmall cell lung cancer. Pharmacogenomics 3(6): 1–18

    Article  Google Scholar 

  • Specht K, Richter T, Müller M et al. (2001) Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissue. Am J Path 158: 419–429

    CAS  PubMed  Google Scholar 

  • Twyman RM, Primrose SB (2003) Techniques patents for SNP genotyping. Pharmacogenomics 4(1): 67–79

    Article  CAS  PubMed  Google Scholar 

  • Watters JW, McLeod HL (2003) Cancer pharmagenomics: current and future applications. Biochim Biophys Acta 1603: 99–111

    CAS  PubMed  Google Scholar 

  • Winegarden N (2003) Microarrays in cancer: moving from hype to clinical reality. The Lancet 362: 1428

    Article  Google Scholar 

  • Yu JJ, Mu C, Lee KB, et al (1997) A nucleotide polymorphism in ERCC1 in human ovarian cancer cell lines and tumor tissues. Mutat Res 382: 13–20

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Medical Oncology Service Institut Català d’Oncologia, Hospital Germans Trias i Pujol, Crta Canyet, s/n, 08916, Badalona (Barcelona), Spain

    M. Taron, C. Sàrries, J.L. Ramírez & R. Rossell

Authors
  1. M. Taron
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. Sàrries
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J.L. Ramírez
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. Rossell
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer Medizin Verlag Heidelberg

About this chapter

Cite this chapter

Taron, M., Sàrries, C., Ramírez, J., Rossell, R. (2005). Tumorbiologie und moderne Labordiagnostik. In: Pleuramesotheliom. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27329-8_2

Download citation

  • DOI: https://doi.org/10.1007/3-540-27329-8_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-23014-4

  • Online ISBN: 978-3-540-27329-5

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation