Abstract
Although the validation process necessary to ensure that an analytical method is fit for purpose is universal, the emphasis placed on different aspects of that process will vary according to the end use for which the analytical procedure is designed. It therefore becomes difficult to produce a standard method validation protocol which will be totally applicable to all analytical methods. It is probable that far more than 30% of the methods in routine laboratory use have not been validated to an appropriate level to suit the problem at hand. This situation needs to change and a practical assessment of the degree to which a method requires to be validated is the first step to a reliable and cost effective analytical industry.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
ISO/IEC Guide 25 (draft 5 1996] General Requirements for the Competence of Testing and Calibration Laboratories. International Organisation for Standards, Geneva
Taylor JK (1993) Anal Chem 55:600A–608A
Green JM (1996) Anal Chem 68:305A–309A
Thomson M, Wood R (1995) Pure Appl Chem 87: 649–666
Guideline for collaborative study of procedure to validate characteristics of a method of analysis (1989) J Assoc Off Anal Chem 72: 694–704
Price G (1996) Accred Qual Assur 1:57–66
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer-Verlag
About this chapter
Cite this chapter
Wells, R.J. (1998). Validation requirements for chemical methods in quantitative analysis — horses for courses?. In: De Bièvre, P., Günzler, H. (eds) Validation in Chemical Measurement. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27034-5_12
Download citation
DOI: https://doi.org/10.1007/3-540-27034-5_12
Received:
Accepted:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-20788-7
Online ISBN: 978-3-540-27034-8
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)