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Bleeding Tendency of Carriers of Hemophilia A — Dependent on the Age of the Carriers?

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34th Hemophilia Symposium

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References

  1. Srámek A, Kriek M, Rosendaal FR. Decreased mortality of ischaemic heart disease among carriers of haemophilia. Lancet 2003;362:351–4.

    PubMed  Google Scholar 

  2. Lusher JM, McMillan CW. Severe factor VIII and factor IX deficiency in females. Am J Med 1978;65:637–48.

    Article  PubMed  CAS  Google Scholar 

  3. Lyonz MF. Sex chromatin and gene action in the mammalian x-chromosome. Am J Hum Genet 1962;14:135–48.

    Google Scholar 

  4. Gitschier J, Wood WI, Goralka TM, et al. Characterization of the human factor VIII gene. Nature 1984;312:326–30.

    Article  PubMed  CAS  Google Scholar 

  5. Wood WI, Capon DJ, Simonsen CC, et al. Expression of active human factor VIII from recombinant DNA clones. Nature 1984;312:330–7.

    Article  PubMed  CAS  Google Scholar 

  6. Toole JJ, Knopf JL, Wozney JM, et al. Molecular cloning of a cDNA encoding human antihaemophilic factor. Nature 1984;312:342–7.

    Article  PubMed  CAS  Google Scholar 

  7. Higuchi M, Kochhan L, Schwaab R, Egli H, Brackmann HH, Horst J, Olek K. Molecular defects in haemophilia A: identification and characterization of mutations in the factor VIII gene and family analysis. Blood 1989;74:1045–51.

    PubMed  CAS  Google Scholar 

  8. Antonarakis SE, Kazazian HH Jr. The molecular basis of haemophilia A in man. Trends Genet 1988;4:233–7.

    Article  PubMed  CAS  Google Scholar 

  9. Lakich D, Kazazian HH, Antoarakis SE, Gitschier J. Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A. Nature Genetics 1993;5:236–41.

    Article  PubMed  CAS  Google Scholar 

  10. Miesbach W, Vigh T, Stier-Brück I, Oldenburg J, Scharrer I. Bleeding symptoms in carriers of hemophilia A — association to the factor VIII gene mutation? In: Scharrer I, Schramm W (editors). 33rd Hemophilia symposium Hamburg 2002. Springer Verlag Berlin Heidelberg 2004:228–231.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Innere Medizin, Hämophilie-Ambulanz, Klinikum der J.W.Goethe-Universität, D-Frankfurt/Main, Germany

    Dr. W. Miesbach

  2. Blutspendienst Frankfurt/M., D-Frankfurt/Main, Germany

    Dr. J. Oldenburg

  3. Zentum der Inneren Medizin, Hämophilie-Ambulanz, Klinikum der J.W.Goethe-Universität, D-Frankfurt/Main, Germany

    T. Vigh

  4. Zentrum der Inneren Medizin, Hämophilia-Ambulanz, Klinikum der J. W. Goethe-Universität, D-Franfurt/Main, Germany

    Frau Prof. Dr. I. Scharrer

Authors
  1. Dr. W. Miesbach
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  2. Dr. J. Oldenburg
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  3. Dipl-Biochemiker I. Stier-Brück
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  4. T. Vigh
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  5. Frau Prof. Dr. I. Scharrer
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Editor information

Editors and Affiliations

  1. Hemophilia Center, Dept. of Internal Medicine, University Hospital, Theodor-Stern-Kai 7, D-60590, Frankfurt am Main, Germany

    I. Scharrer

  2. Dept. of Hemostaseology, University Hospital, Ziemssenstr. 1a, D-80336, München, Germany

    W. Schramm

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© 2005 Springer Medizin Verlag Heidelberg

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Miesbach, W., Oldenburg, J., Stier-Brück, I., Vigh, T., Scharrer, I. (2005). Bleeding Tendency of Carriers of Hemophilia A — Dependent on the Age of the Carriers?. In: Scharrer, I., Schramm, W. (eds) 34th Hemophilia Symposium. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27022-1_30

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  • DOI: https://doi.org/10.1007/3-540-27022-1_30

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-22886-8

  • Online ISBN: 978-3-540-27022-5

  • eBook Packages: MedicineMedicine (R0)

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