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Diagnostics of Platelet Function Disorders by Lumi-Aggregometry — Results and Comparison of Methods

  • Conference paper
34th Hemophilia Symposium

Conclusions

The lumi-aggregometry is a useful method for detection of platelet function disorders. The results correspond well with those obtained from aggregometry in PRP which is one the most established platelet function test in the clinical laboratory. However, lumi-aggregometry is superior because of the smaller blood volume requirement which is important especially in pediatrics, the measurement in the more physiologic whole blood environment and the minimal sample manipulation. The bleeding time as in-vivo test is needed to clarify the bleeding tendency in patients with disturbed primary hemostasis. The PFA 100 test seems to be only partially suitable for the detection of platelet function disorders in children.

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Author information

Authors and Affiliations

  1. Klinik und Poliklinik für Kinderheilkunde, Carl Gustav Carus-Universität, D-Dresden, Germany

    Dr. R. Knoefler

  2. D-Dresden, Germany

    Prof. Dr. G. Weissbach

Authors
  1. Dr. R. Knoefler
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  2. G. Siegert
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  3. E. Kuhlisch
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  4. Prof. Dr. G. Weissbach
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Editor information

Editors and Affiliations

  1. Hemophilia Center, Dept. of Internal Medicine, University Hospital, Theodor-Stern-Kai 7, D-60590, Frankfurt am Main, Germany

    I. Scharrer

  2. Dept. of Hemostaseology, University Hospital, Ziemssenstr. 1a, D-80336, München, Germany

    W. Schramm

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© 2005 Springer Medizin Verlag Heidelberg

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Knoefler, R., Siegert, G., Kuhlisch, E., Weissbach, G. (2005). Diagnostics of Platelet Function Disorders by Lumi-Aggregometry — Results and Comparison of Methods. In: Scharrer, I., Schramm, W. (eds) 34th Hemophilia Symposium. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27022-1_17

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  • DOI: https://doi.org/10.1007/3-540-27022-1_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-22886-8

  • Online ISBN: 978-3-540-27022-5

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