Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Dahn MS, Lange P, Lobdell K, et al (1987). Splanchnic and total body oxygen consumption differences in septic and injured patients. Surgery 101:69–80
De Backer D, Creteur J, Noordally O, et al (1998) Does hepato-splanchnic VO2/DO2 dependency exist in critically ill septic patients? Am J Respir Crit Care Med 157:1219–1225
Zhao KS, Junker D, Delano FA, et al (1985) Microvascular adjustments during irreversible hemorrhagic shock in rat skeletal muscle. Microvasc Res 30:143–153
Dammers R, Wehrens XH, oude Egbrink MG, Slaaf DW, Kurvers HA, Ramsay G (2001) Microcirculatory effects of experimental acute limb ischaemia-reperfusion. Br J Surg 88:816–824
Cryer HM, Garrison RN, Kaebnick HW, Harris PD, Flint LM (1987) Skeletal microcirculatory responses to hyperdynamic Escherichia coli sepsis in unanesthetized rats. Arch Surg 122:86–92
Baker CH, Wilmoth FR (1984) Microvascular responses to E. coli endotoxin with altered adrenergic activity. Circ Shock 12:165–176
Lam CJ, Tyml K, Martin CM, Sibbald W (1994) Microvascular perfusion is impaired in a rat model of normotensive sepsis. J Clin Invest 94:2077–2083
Piper R D, Pitt-Hyde ML, Anderson L A, et al (1998) Leukocyte activation and flow behavior in rat skeletal muscle in sepsis. Am J Respir Crit Care Med 157:129–134
Piper RD, Pitt-Hyde M, Li F, Sibbald WJ, Potter RF (1996) Microcirculatory changes in rat skeletal muscle in sepsis. Am J Respir Crit Care Med 154:931–937
Farquhar I, Martin CM, Lam C, Potter R, Ellis CJ, Sibbald WJ (1996) Decreased capillary density in vivo in bowel mucosa of rats with normotensive sepsis. J Surg Res 61:190–196
McCuskey RS, Urbaschek R, Urbaschek B (1996) The microcirculation during endotoxemia. Cardiovasc Res 32:752–763
Boczkowski J, Vicaut E, Aubier M (1992) In vivo effects of Escherichia coli endotoxemia on diaphragmatic microcirculation in rats. J Appl Physiol 72:2219–2224
Nakajima Y, Baudry N, Duranteau J, et al (2001) Microcirculation in Intestinal Villi. A comparison between hemorrhagic and endotoxin shock. Am J Respir Crit Care Med 164:1526–1530
Drazenovic R, Samsel RW, Wylam ME, Doerschuk DM, Schumacker PT (1992) Regulation of perfused capillary density in canine intestinal mucosa during endotoxemia. J Appl Physiol 72:259–265
Ellis CG, Bateman RM, Sharpe MD, Sibbald WJ, Gill R (2002) Effect of a maldistribution of microvascular blood flow on capillary O(2) extraction in sepsis. AmJ Physiol 282:H156–H164
Vicaut E, Hou X, Payen D, Bousseau A, Tedgui A (1991). Acute effects of tumor necrosis factor on the microcirculation in rat cremaster muscle. J Clin Invest 87:1537–1540
Groeneveld AB, Hartemink KJ, de Groot MC, Visser J, Thijs LG (1999) Circulating endothelin and nitrate-nitrite relate to hemodynamic and metabolic variables in human septic shock. Shock 11:160–166
Hollenberg SM, Broussard M, Osman J, Parrillo JE (2000) Increased microvascular reactivity and improved mortality in septic mice lacking inducible nitric oxide synthase. Circ Res 86:774–778
Diaz NL, Finol HJ, Torres SH, Zambrano CI, Adjounian H (1998) Histochemical and ultrastructural study of skeletal muscle in patients with sepsis and multiple organ failure syndrome (MOFS). Histol Histopathol 13:121–128
Schneider J (1993) Fibrin-specific lysis of microthrombosis in endotoxemic rats by saruplase. Thromb Res 72:71–82
Drost EM, Kassabian G, Meiselman HJ, et al (1999) Increased rigidity and priming of polymorphonuclear leukocytes in sepsis. Am J Respir Crit Care Med 159:1696–1702
Astiz ME, DeGent GE, Lin RY, Rackow EC (1995) Microvascular function and rheologic changes in hyperdynamic sepsis. Crit Care Med 23:265–271
Kirschenbaum LA, Astiz ME, Rackow EC, Saha DC, Lin R (2000) Microvascular response in patients with cardiogenic shock. Crit Care Med 28:1290–1294
Eichelbronner O, Sielenkamper A, Cepinskas G, et al (2000) Endotoxin promotes adhesion of human erythrocytes tohuman vascular endothelial cells under conditions of flow. Crit Care Med 28:1865–1870
Walley KR. (1996)Heterogeneity of oxygen delivery impairs oxygen extraction by peripheral tissues: theory. J Appl Physiol 81:885–894
Humer MF, Phang PT, Friesen BP, et al (1996) Heterogeneity of gut capillary transit times and impaired gut oxygen extraction in endotoxemic pigs. J Appl Physiol 81:895–904
Ince C, Sinaasappe lM (1999) Microcirculatory oxygenation and shunting in sepsis and shock. Crit Care Med 27:1369–1377
Zuurbier CJ, van Iterson M, Ince C (1999) Functional heterogeneity of oxygen supply-consumption ratio in the heart. Cardiovasc Res 44:488–497
De Backer D, Creteur J, Dubois MJ (2003) Microvascular alterations in patients with circulatory failure. In: Vincent JL (ed) Yearbook of Intensive Care and Emergency Medicine Springer, Heidelberg, pp 535–544
De Backer D, Dubois MJ (2001) Assessment of the microcirculatory flow in patients in the intensive care unit. Curr Opin Crit Care 7:200–203
Groner W, Winkelman JW, Harris AG, et al (1999) Orthogonal polarization spectral imaging: a new method for study of the microcirculation. Nat Med 5:1209–1212
Mathura KR, Vollebregt KC, Boer K, et al (2001) Comparison of OPS imaging and conventional capillary microscopy to study the human microcirculation. J Appl Physiol 91:74–78
Langer S, von Dobschuetz E, Harris AG, Krombach F, Messmer K (2000) Validation of the orthogonal polarization spectral imaging technique on solid organs. In: Messmer K (ed) Orthogonal Polarization Spectral Imaging, Progress in Applied Microcirculation vol 24. Karger, Basel, pp 32–46
Laemmel E, Tadayoni R, Sinitsina I, Boczkowski J, Vicaut E (2000). Using orthogonal polarization spectral imaging for the experimental study of microcirculation: comparison with intravital microscopy. In: Messmer K (ed) Orthogonal Polarization Spectral Imaging, Progress in Applied Microcirculation vol 24. Karger, Basel, pp 50–60.
Harris AG, Sinitsina I, Messmer K (2000) The Cytoscan(TM) Model E-II, a new reflectance microscope for intravital microscopy: Comparison with the standard fluorescence method. J Vasc Res 37:469–476
De Backer D, Creteur J, Preiser JC, et al (2002) Microvascular blood flow is altered in patients with sepsis. Am J Respir Crit Care Med 166:98–104
Freedlander SO, Lenhart CH (1922) Clinical observations on the capillary circulation. Arch Intern Med 29:12–32
Young JD, Cameron EM (1995) Dynamics of skin blood flow in human sepsis. Intensive Care Med 21:669–674
Stucker M, Steinberg J, Memmel U, et al (2001) Differences in the two-dimensionally measured laser Doppler flow at different skin localisations. Skin Pharmacol Appl Skin Physiol 14:44–51
Neviere R, Mathieu D, Chagnon JL, et al (1996) Skeletal muscle microvascular blood flow and oxygen transport in patients with severe sepsis. Am J Respir Crit Care Med 153:191–195
De Backer D, Creteur J, Dubois MJ, Sakr Y, Vincent JL (2004) Microvascular alterations in patients with acute severe heart failure and cardiogenic shock. Am Heart J 147:91–99
Buwalda M, Ince C (2002) Opening the microcirculation: can vasodilators be useful in sepsis? Intensive Care Med 28:1208–1217
Spronk PE, Ince C, Gardien MJ, et al (2002) Nitroglycerin in septic shock after intravascular volume resuscitation. Lancet 360:1395–1396
Dubois MJ, De Backer D, Schmartz D, et al (2002) Microcirculatory alterations in cardiac surgery with and without cardiopulmonary bypass. Intensive Care Med 28:S76 (abst)
Tugtekin I, Radermacher P, Theisen M, et al (2001) Increased ileal-mucosal-arterial PCO2 gap is associated with impaired villus microcirculation in endotoxic pigs. Intensive Care Med 27:757–766
LeDoux D, Astiz ME, Carpati CM, Rackow EC (2000) Effects of perfusion pressure on tissue perfusion in septic shock. Crit Care Med 28:2729–2732
De Backer D, Sakr Y, Creteur J, et al (2003) Microvascular alterations are independent of systemic factors in patients with septic shock. Intensive Care Med 29:S10 (abst)
Corso CO, Gundersen Y, Dörger M, et al (1998) Effects of nitric oxide synthase inhibitors NG-nitro-L-arginine methyl eshter and aminoethyl-isothiourea on the liver microcirculation in rat endotoxemia. J Hepatol 28:61–69
Foitzik T, Eibl G, Hotz HG, et al (2000) Endothelin receptor blockade in severe acute pancreatitis leads to systemic enhancement of microcirculation, stabilization of capillary permeability, and improved survival rates. Surgery 128:399–407
Spronk PE, Rommes JH, Hesselink EJ, et al (2003) Comparison of sublingual and intestinal microvascular flow in critically ill patients. Intensive Care Med 29:S179 (abst)
Kerger H, Waschke KF, Ackern KV, Tsai AG, Intaglietta M (1999) Systemic and microcirculatory effects of autologous whole blood resuscitation in severe hemorrhagic shock. Am J Physiol 276:H2035–H2043
Sakr Y, Dubois MJ, De Backer D, et al (2002) Time course of microvascular alterations in patients with septic shock. Intensive Care Med 28:S15 (abst)
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
De Backer, D. (2005). Microcirculatory Blood Flow: Videomicroscopy. In: Pinsky, M.R., Payen, D. (eds) Functional Hemodynamic Monitoring. Update in Intensive Care and Emergency Medicine, vol 42. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26900-2_17
Download citation
DOI: https://doi.org/10.1007/3-540-26900-2_17
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-22349-8
Online ISBN: 978-3-540-26900-7
eBook Packages: MedicineMedicine (R0)