Skip to main content

Postoperative Übelkeit und Erbrechen

  • Chapter
  • 924 Accesses

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   74.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Andrews PLR (1992) Physiology of nausea and vomiting. Br J Anaesth 69: S2–19

    Google Scholar 

  2. Apfel CC, Greim CA, Goepfert C, Grundt D, Usadel J, Sefrin P, Roewer N (1998) Postoperatives Erbrechen: Ein Score zur Voraussage des Erbrechensrisikos nach Inhalationsanästhesien. Anästhesist 47: 732–740

    CAS  Google Scholar 

  3. Apfel CC, Greim CA, Haubitz I, Goepfert C, Usadel J, Sefrin P, Roewer N (1998) A risk score to predict the probability of postoperative vomiting in adults. Acta Anaesthesiol Scand 42: 495–501

    PubMed  CAS  Google Scholar 

  4. Apfel CC, Greim CA, Haubitz I, Grundt D, Goepfert C, Sefrin P, Roewer N (1998) The discriminating power of a risk score for postoperative vomiting in adults undergoing various types of surgery. Acta Anaesthesiol Scand 42: 502–509

    PubMed  CAS  Google Scholar 

  5. Apfel CC, Laara E, Koivuranta M, Greim CA, Roewer N (1999) A simplified risk score for predicting postoperative nausea and vomiting: Conclusions from crossvalidations between two centers. Anesthesiology 91: 693–700

    PubMed  CAS  Google Scholar 

  6. Apfel CC, Roewer N (2000) Einflussfaktoren von Uebelkeit und Erbrechen nach Narkosen: Fiktionen und Fakten. Anästhesist 49: 629–641

    CAS  Google Scholar 

  7. Apfel CC, Kranke P, Greim CA, Roewer N (2001) What can be expected from risk scores for predicting postoperative nausea and vomiting? Br J Anaesth 86: 822–827

    Article  PubMed  CAS  Google Scholar 

  8. Apfel CC, Kranke P, Eberhart LHJ, Roos IA, Roewer N (2002) A comparison of predicting models for postoperative nausea and vomiting. Br J Anaesth 88: 234–240

    PubMed  CAS  Google Scholar 

  9. Apfel CC, Kranke P, Katz MH, Goepfert C, Papenfuss T, Rauch S, Heineck R, Greim CA, Roewer N (2002) Volatile anaesthetics may be the main cause for early but not delayed postoperative nausea and vomiting: a randomized controlled trial of factorial design. British Journal of Anaesthesia 88: 659–668

    PubMed  CAS  Google Scholar 

  10. Apfel CC, Koivuranta M, Sweeney B, Thomas R, Jones N, Strike P (2003) Study of postoperative nausea and vomiting: recommending risk models for group comparisons. Anaesthesia 58: 492–493

    Article  PubMed  CAS  Google Scholar 

  11. Apfel CC, Korttila K, Abdalla M, Biedler A, Pocock S, Roewer N (2003) An International Multicenter Protocol to Assess the Single and Combined Benefits of Antiemetic Strategies in a Controlled Clinical Trial of a 2x2x2x2x2x2 factorial design (IMPACT). Controlled Clinical Trials 24: 736–751

    Article  PubMed  Google Scholar 

  12. Apfel CC et al. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. New England Journal of Medicine 2004; 50(24): 2441–2451

    Google Scholar 

  13. Barnes NM, Bunce KT, Naylor RJ, Rudd JA (1991) The actions of fentanyl to inhibit drug-induced emesis. Neuropharmacology 30:1073–1083

    PubMed  CAS  Google Scholar 

  14. Biedler A, Wilhelm W (1998) Postoperative Übelkeit und Erbrechen. Anästhesist 47:145–158

    CAS  Google Scholar 

  15. Boeke AJ, de Lange JJ, van Druenen B, Langemeijer JJ (1994) Effect of antagonizing residual neuromuscular block by neostigmine and atropine on postoperative vomiting. Br J Anaesth 72:654–656

    PubMed  CAS  Google Scholar 

  16. Breitfeld C, Peters J, Vockel T, Lorenz C, Eikermann M (2003) Emetic effects of morphine and piritramide. Br J Anaesth 91:218–223

    Article  PubMed  CAS  Google Scholar 

  17. Bremner WG, Kumar CM (1993) Delayed surgical emphysema, pneumomediastinum and bilateral pneumothoraces after postoperative vomiting. Br J Anaesth 71:296–297

    PubMed  CAS  Google Scholar 

  18. Cheatham ML, Chapman WC, Key SP, Sawyers JL (1995) A meta-analysis of selective vs. routine nasogastric decompression after elective laparotomy. Ann Surg 221:469–478

    PubMed  CAS  Google Scholar 

  19. Cohen MM, Duncan PG, DeBoer DP, Tweed WA (1994) The postoperative interview: assessing risk factors for nausea and vomiting. Anesth Analg 78:7–16

    PubMed  CAS  Google Scholar 

  20. Costello DJ, Borison HL (1977) Naloxone antagonizes narcotic self blockade of emesis in the cat. J Pharmacol Exp Ther 203:222–230

    PubMed  CAS  Google Scholar 

  21. Culebras X, Corpataux JB, Gaggero G, Tramer MR (2003) The antiemetic efficacy of droperidol added to morphine patient-controlled analgesia: a randomized, controlled, multicenter dose-finding study. Anesth Analg 97:816–821

    PubMed  CAS  Google Scholar 

  22. Divatia JV, Vaidya JS, Badwe RA, Hawaldar RW (1996) Omission of nitrous oxide during anesthesia reduces the incidence of postoperative nausea and vomiting. A meta-analysis. Anesthesiology 85:1055–1062

    PubMed  CAS  Google Scholar 

  23. Eberhart LH, Morin AM, Felbinger TW, Falkner Y, Georgieff M, Seeling W (1998) Ergebnisse einer Umfrage unter Anasthesisten zum Thema Ubelkeit und Erbrechen in der postoperativen Phase. Anesthesiol Intensivmed Notfallmed Schmerzther 33:545–551

    CAS  Google Scholar 

  24. Eberhart LH, Hogel J, Seeling W, Staack AM, Geldner G, Georgieff M (2000) Evaluation of three risk scores to predict postoperative nausea and vomiting. Acta Anaesthesiol Scand 44:480–488

    PubMed  CAS  Google Scholar 

  25. Eberhart LH, Morin AM, Georgieff M (2000) Menstruationszyklus in der postoperativen Phase: Der Einfluss auf die Inzidenz von Übelkeit und Erbrechen. Anästhesist 49:532–535

    CAS  Google Scholar 

  26. Eberhart LH, Morin AM, Georgieff M (2000) Dexamethason zur Prophylaxe von Übelkeit und Erbrechen in der postoperativen Phase. Eine Meta-analyse kontrollierter randomisierter Studien. Anästhesist 49:713–720

    CAS  Google Scholar 

  27. Eberhart LHJ, Morin AM, Seeling W, Bothner U, Georgieff M (1999) Metaanalyse kontrollierter randomisierter Studien zum Einsatz von Droperidol zur Prophylaxe von Übelkeit und Erbrechen in der postoperativen Phase. Anesthesiol Intensivmed Notfallmed Schmerzther 34:528–536

    CAS  Google Scholar 

  28. Eberhart LHJ, Mauch M, Morin AM, Wulf H, Geldner G (2002) Impact of a multimodal anti-emetic prophylaxis on patient satisfaction in high-risk patients for postoperative nausea and vomiting. Anaesthesia 57:1022–1027

    Article  PubMed  CAS  Google Scholar 

  29. Forrest JB, Cahalan MK, Rehder K, Goldsmith CH, Levy WJ, Strunin L, Bota W, Boucek CD, Cucchiara RF, Dhamee S, et al. (1990) Multicenter study of general anesthesia. II. Results. Anesthesiology 72:262–268

    PubMed  CAS  Google Scholar 

  30. Foster PN, Stickle BR, Laurence AS (1996) Akathisia following low-dose droperidol for antiemesis in day-case patients. Anaesthesia 51:491–494

    PubMed  CAS  Google Scholar 

  31. Gan T, Sloan F, Dear G, El Moalem HE, Lubarsky DA (2001) How much are patients willing to pay to avoid postoperative nausea and vomiting? Anesth Analg 92:393–400

    PubMed  CAS  Google Scholar 

  32. Gan T, Meyer T, Apfel C, Chung F, Davis P, Eubanks S, Kovac A, Philip B, Sessler D, Temo J, Tramèr M, Watcha M (2003) Consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg 97:62–71

    PubMed  Google Scholar 

  33. Gan TJ, White PF, Scuderi PE, Watcha MF, Kovac A (2002) FDA ≫black box≪ warning regarding use of droperidol for postoperative nausea and vomiting: is it justified? Anesthesiology 97:287

    Article  PubMed  Google Scholar 

  34. Hechler A, Naujoks F, Ataman K, Hopf HB (1999) Die Inzidenz an postoperativer Übelkeit und Erbrechen ist unabhaengig von der routinemaessigen Maskenvorbeatmung waehrend der Narkoseeinleitung. Anesthesiol Intensivmed Notfallmed Schmerzther 34:684–688

    CAS  Google Scholar 

  35. Henzi I, Walder B, Tramer MR (1999) Metoclopramide in the prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized, placebocontrolled studies. Br J Anaesth 83:761–771

    PubMed  CAS  Google Scholar 

  36. Hill RP, Lubarsky DA, Phillips-Bute B, Fortney JT, Creed MR, Glass PS, Gan TJ (2000) Cost-effectiveness of prophylactic antiemetic therapy with ondansetron, droperidol, or placebo. Anesthesiology 92:958–967

    PubMed  CAS  Google Scholar 

  37. Hofer CK, Zollinger A, Buchi S, Klaghofer R, Serafino D, Buhlmann S, Buddeberg C, Pasch T, Spahn DR (2003) Patient well-being after general anaesthesia: a prospective, randomized, controlled multi-centre trial comparing intravenous and inhalation anaesthesia. Br J Anaesth 91:631–637

    Article  PubMed  CAS  Google Scholar 

  38. Junger A, Hartmann B, Benson M, Schindler E, Dietrich G, Jost A, Bye-Basse A, Hempelmannn G (2001) The use of an anesthesia information management system for prediction of antiemetic rescue treatment at the postanesthesia care unit. Anesth Analg 92:1203–1209

    PubMed  CAS  Google Scholar 

  39. Kazemi-Kjellberg F, Henzi I, Tramer MR (2001) Treatment of established postoperative nausea and vomiting: a quantitative systematic review. BMC Anesthesiol 1:2

    Article  PubMed  Google Scholar 

  40. Klockgether-Radke A, Demmel C, Braun U, Muehlendyck H (1993) Erbrechen und okulocardialer Reflex. Anästhesist 42:356–360

    CAS  Google Scholar 

  41. Koivuranta M, Laara E, Snare L, Alahuhta S (1997) A survey of postoperative nausea and vomiting. Anaesthesia 52: 443–449

    Article  PubMed  CAS  Google Scholar 

  42. Kovac AL, O’ Connor TA, Pearman MH, Kekoler LJ, Edmondson D, Baughman VL, Angel JJ, Campbell C, Jense HG, Mingus M, Shahvari MB, Creed MR (1999) Efficacy of repeat intravenous dosing of ondansetron in controlling postoperative nausea and vomiting: a randomized, double-blind, placebo-controlled multicenter trial. J Clin Anesth 11:453–459

    PubMed  CAS  Google Scholar 

  43. Kovac AL (2000) Prevention and treatment of postoperative nausea and vomiting. Drugs 59:213–243

    PubMed  CAS  Google Scholar 

  44. Kranke P, Apfel CC, Papenfuss T, Rauch S, Lobmann U, Rubsam B, Greim CA, Roewer N (2001) An increased body mass index is no risk factor for postoperative nausea and vomiting. A systematic review and results of original data. Acta Anaesthesiol Scand 45:160–166

    PubMed  CAS  Google Scholar 

  45. Kranke P, Morin AM, Roewer N, Eberhart LH (2002) Dimenhydrinate for prophylaxis of postoperative nausea and vomiting: a meta-analysis of randomized controlled trials. Acta Anaesthesiol Scand 46:238–244

    Article  PubMed  CAS  Google Scholar 

  46. Kranke P, Morin AM, Roewer N, Wulf H, Eberhart LH (2002) The efficacy and safety of transdermal scopolamine for the prevention of postoperative nausea and vomiting: a quantitative systematic review. Anesth Analg 95:133–143

    PubMed  CAS  Google Scholar 

  47. Kretz FJ (1997) Postoperatives Erbrechen: Medikamentoese Prophylaxe und Therapie mit etablierten Substanzen beim Kind. Anesthesiol Intensivmed Notfallmed Schmerzther 32:620–622

    CAS  Google Scholar 

  48. Lim BS, Pavy TJ, Lumsden G (1999) The antiemetic and dysphoric effects of droperidol in the day surgery patient. Anaesthesia and Intensive Care 27:371–374

    PubMed  CAS  Google Scholar 

  49. Lischke V, Behne M, Doelken P, Schledt U, Probst S, Vettermann J (1994) Droperidol causes a dose-dependent prolongation of the QT interval. Anesth Analg 79:983–986

    PubMed  CAS  Google Scholar 

  50. Liu K, Hsu CC, Chia YY (1999) The effect of dose of dexamethasone for antiemesis after major gynecological surgery. Anesth Analg 89:1316–1318

    PubMed  CAS  Google Scholar 

  51. Macario A, Weinger M, Carney S, Kim A (1999) Which clinical anesthesia outcomes are important to avoid? The perspective of patients. Anesth Analg 89:652–658

    PubMed  CAS  Google Scholar 

  52. Melnick B, Sawyer R, Karambelkar D, Phitayakorn P, Uy NT, Patel R (1989) Delayed side effects of droperidol after ambulatory general anesthesia. Anesth Analg 69:748–751

    PubMed  CAS  Google Scholar 

  53. Palazzo M, Evans R (1993) Logistic regression analysis of fixed patient factors for postoperative sickness: a model for risk assessment. Br J Anaesth 70:135–140

    PubMed  CAS  Google Scholar 

  54. Pierre S, Benais H, Pouymayou J (2002) Apfel’s simplified score may favourably predict the risk of postoperative nausea and vomiting. Can J Anesth 49:237–242

    Article  PubMed  Google Scholar 

  55. Rauch S, Apfel CC, Loebmann U, Sefrin P, Roewer N (1998) Zeitliche Verteilung postoperativen Erbrechens bei Kindern und Erwachsenen. Anesthesiol Intensivmed Notfallmed Schmerzther 33:S165

    Google Scholar 

  56. Rose JB, Watcha MF (1999) Postoperative nausea and vomiting in paediatric patients. Br J Anaesth 83:104–117

    PubMed  CAS  Google Scholar 

  57. Rusch D, Happe W, Wulf H (1999) Postoperative Übelkeit und postoperatives Erbrechen nach Strabismuschirurgie bei Kindern. Inhalationsanästhesie mit Sevofluran/Lachgas im Vergleich zu intravenöser Anästhesie mit Propofol/ Remifentanil. Anästhesist 48:80–88

    CAS  Google Scholar 

  58. Scuderi PE, James RL, Harris L, Mims GR (1999) Antiemetic prophylaxis does not improve outcomes after outpatient surgery when compared to symptomatic treatment. Anesthesiology 90:360–371

    PubMed  CAS  Google Scholar 

  59. Scuderi PE, James RL, Harris L, Mims GR, III (2000) Multimodal antiemetic management prevents early postoperative vomiting after outpatient laparoscopy. Anesth Analg 91:1408–1414

    PubMed  CAS  Google Scholar 

  60. Sinclair DR, Chung F, Mezei G (1999) Can postoperative nausea and vomiting be predicted? Anesthesiology 91:109–118

    Article  PubMed  CAS  Google Scholar 

  61. Sneyd JR, Carr A, Byrom WD, Bilski AJ (1998) A meta-analysis of nausea and vomiting following maintenance of anaesthesia with propofol or inhalational agents. Eur J Anaesthesiol 15:433–445

    Article  PubMed  CAS  Google Scholar 

  62. Stadler M, Bardiau F, Seidel L, Albert A, Boogaerts JG (2003) Difference in risk factors for postoperative nausea and vomiting. Anesthesiology 98:46–52

    Article  PubMed  Google Scholar 

  63. Thomas R, Jones NA, Strike P (2002) The value of risk scores for predicting postoperative nausea and vomiting when used to compare patient groups in a randomised controlled trial. Anaesthesia 57:1119–1128

    PubMed  CAS  Google Scholar 

  64. Thompson PI, Bingham S, Andrews PL, Patel N, Joel SP, Slevin ML (1992) Morphine 6-glucuronide: a metabolite of morphine with greater emetic potency than morphine in the ferret. Br J Pharmacol 106:3–8

    PubMed  CAS  Google Scholar 

  65. Tramer MR, Reynolds DJ, Moore RA, McQuay HJ (1997) Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized placebo-controlled trials. Anesthesiology 87:1277–1289

    PubMed  CAS  Google Scholar 

  66. Tramer MR, Fuchs-Buder T (1999) Omitting antagonism of neuromuscular block: effect on postoperative nausea and vomiting and risk of residual paralysis. A systematic review. Br J Anaesth 82:379–386

    PubMed  CAS  Google Scholar 

  67. Verheecke G, Apfel CC (2003) Early postoperative vomiting and volatile anaesthetics or nitrous oxide. Br J Anaesth 90:109–110

    Article  PubMed  CAS  Google Scholar 

  68. Wang JJ, Ho ST, Lee SC, Liu YC, Ho CM (2000) The use of dexamethasone for preventing postoperative nausea and vomiting in females undergoing thyroidectomy: a dose-ranging study. Anesth Analg 91:1404–1407

    PubMed  CAS  Google Scholar 

  69. Wang JJ, Ho ST, Tzeng JI, Tang CS (2000) The effect of timing of dexamethasone administration on its efficacy as a prophylactic antiemetic for postoperative nausea and vomiting. Anesth Analg 91:136–139

    PubMed  CAS  Google Scholar 

  70. Watcha MF (2000) The cost-effective management of postoperative nausea and vomiting. Anesthesiology 92:931–933

    PubMed  CAS  Google Scholar 

  71. Watcha MF (2002) Postoperative nausea and emesis. Anesthesiol Clin North America 20:471–484

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer Medizin Verlag Heidelberg

About this chapter

Cite this chapter

Apfel, C.C. (2005). Postoperative Übelkeit und Erbrechen. In: Evidenzbasierte Medizin in Anästhesie und Intensivmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26858-8_14

Download citation

  • DOI: https://doi.org/10.1007/3-540-26858-8_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-20042-0

  • Online ISBN: 978-3-540-26858-1

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics