Zusammenfassung
Ösophagusvarizen gehören zu den Hauptmanifestationsformen der portalen Hypertension. Ihr klinisches Erscheinungsbild wird durch die akute Blutung bestimmt. Die durchschnittliche Mortalität einer akuten Ösophagusvarizenblutung liegt zwischen 30 und 50%. Die meisten Todesfälle treten im Rahmen einer frühen Rezidivblutung innerhalb der ersten Woche auf.
Die Therapieoptionen zur Behandlung und Rezidivprophylaxe von blutenden Ösophagusvarizen schließen medikamentöse, endoskopische, radiologische und chirurgische Behandlungsmaßnahmen ein. Alle diese Therapiemöglichkeiten haben sich weiterentwickelt. Dies führte zu einer exakteren Definition der Rolle der einzelnen Verfahren. Endoskopische Sklerotherapie und Varizenligatur sind der »golden standard« der akuten Blutung. In der weiteren Behandlungsstrategie werden nichtchirurgische und chirurgische Verfahren sequenziell und komplementär im Rahmen multimodaler Therapiekonzepte eingesetzt.
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Menke, D., Witzigmann, H., Wehrmann, T., Uhlmann, D., Hauss, J. (2005). Ösophagusvarizenblutung. In: Caspary, W.F., Mössner, J., Stein, J. (eds) Therapie gastroenterologischer Krankheiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26660-7_6
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