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Systematischer Vergleich der Testverfahren

  • Henriette Schleberger
  • Dorothea Gadzicki
  • Brigitte Schlegelberger
  • Ansgar Gerhardus
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Eingeschlossene Literatur

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  2. [2]
    [2]_Arnold N, Gross E, Schwarz-Boeger U, Pfisterer J, Jonat W, Kiechle M. (1999) A highly sensitive, fast, and economical technique for mutation analysis in hereditary breast and ovarian cancers. Hum Mutat 14:333–339.CrossRefPubMedGoogle Scholar
  3. [3]
    [3]_Casadei S, Cortesi L, Pensotti V et al. (2001) Detection of germline BRCA1 mutations by Multiple-Dye Cleavase Fragment Length Polymorphism (MD-CFLP) method. Br J Cancer 85: 845–849.CrossRefPubMedGoogle Scholar
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    [4]_Eng C, Brody LC, Wagner TM et al. (2001) Interpreting epidemiological research: blinded comparison of methods used to estimate the prevalence of inherited mutations in BRCA1. J Med Genet 38: 824–833.CrossRefPubMedGoogle Scholar
  5. [5]
    [5]_Ganguly T, Dhulipala R, Godmilow L, Ganguly A. (1998) High throughput fluorescence-based conformation-sensitive gel electrophoresis (F-CSGE) identifies six unique BRCA2 mutations and an overall low incidence of BRCA2 mutations in high-risk BRCA1-negative breast cancer families. Hum Genet 102:549–556.CrossRefPubMedGoogle Scholar
  6. [6]
    [6]_Gross E, Arnold N, Goette J, Schwarz-Boeger U, Kiechle M. (1999) A comparison of BRCA1 mutation analysis by direct sequencing, SSCP and DHPLC. Hum Genet 105: 72–78.CrossRefPubMedGoogle Scholar
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    [7]_Jakubowska A, Gorski B, Byrski T et al. (2001) Detection of germline mutations in the BRCA1 gene by RNA-based sequencing. Hum Mutat 18: 149–156.PubMedGoogle Scholar
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    [8]_Kringen P, Egedal S, Pedersen JC et al. (2002) BRCA1 mutation screening using restriction endonuclease fingerprinting-single-strand conformation polymorphism in an automated capillary electrophoresis system. Electrophoresis 23: 4085–4091.CrossRefPubMedGoogle Scholar
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    [9]_Rothfuss A, Schutz P, Bochum S et al. (2000) Induced micronucleus frequencies in peripheral lymphocytes as a screening test for carriers of a BRCA1 mutation in breast cancer families. [see comment]. Cancer Res. 60: 390–394.PubMedGoogle Scholar
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    [10]_Sakayori M, Kawahara M, Shiraishi K et al. (2003) Evaluation of the diagnostic accuracy of the stop codon (SC) assay for identifying protein-truncating mutations in the BRCA1and BRCA2genes in familial breast cancer. J Hum Genet 48: 130–137. PubMedGoogle Scholar

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Copyright information

© Springer Medizin Verlag Heidelberg 2005

Authors and Affiliations

  • Henriette Schleberger
    • 1
  • Dorothea Gadzicki
    • 2
  • Brigitte Schlegelberger
    • 2
  • Ansgar Gerhardus
    • 1
    • 3
  1. 1.Abteilung Epidemiologie, Sozialmedizin und GesundheitssystemforschungMedizinische Hochschule HannoverHannover
  2. 2.Abteilung für Zell- und MolekularpathologieMedizinische Hochschule HannoverHannover
  3. 3.Institut für Gesundheits- und MedizinrechtUniversität Bremen, FB 6Bremen

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