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Literatur

  • Acosta JJ, San Roman JI, Lopez MA, Calvo JJ (2000) Influence of chronic ethanol consumption on the muscarinic cholinergic control of rat pancreatic acinar cells. J Physiol Biochem 56: 145–154

    PubMed  Google Scholar 

  • Ammann RW (1997) A clinically based classification system for alcoholic chronic pancreatitis: Summary of an international workshop on chronic pancreatitis. Pancreas 14: 215–221

    PubMed  Google Scholar 

  • Ammann RW, Akovbiantz A, Largiader F, Schueler G (1984) Course and outcome of chronic pancreatitis. Longitudinal study of a mixed medical-surgical series of 245 patients. Gastroenterology 86: 820–828

    PubMed  Google Scholar 

  • Ammann RW, Heitz PhU, Klöppel G (1996) Course of alcoholic chronic pancreatitis: a prospective clinicomorphological long term study. Gastroenterology 111: 224–231

    Article  PubMed  Google Scholar 

  • Apte MV, Haber PS, Applegate TL et al. (1998) Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture. Gut 43: 128–133

    PubMed  Google Scholar 

  • Apte MV, Phillips PA, Fahmy RG et al. (2000) Does alcohol directly stimulate pancreatic fibrogenesis? Studies with rat pancreatic stellate cells. Gastroenterology 118: 780–794

    PubMed  Google Scholar 

  • Apte MV, Wilson JS (2002) Experimental models of pancreatic fibrogenesis and the role of stellate cells. In: Büchler MW, Friess H, Uhl W, Malfertheiner P (eds) Chronic pancreatitis. Blackwell, Berlin, pp 134–147

    Google Scholar 

  • Apte MV, Wilson JS, Korsten MA, McCaughan GW, Haber PS, Pirola RC (1995a) Effects of ethanol and protein deficiency on pancreatic digestive and lysosomal enzymes. Gut 36: 287–293

    PubMed  Google Scholar 

  • Apte MV, Wilson JS, McCaughan GW, Korsten MA, Haber PS, Norton ID, Pirola RC (1995b) Ethanol-induced alterations in messenger RNA levels correlate with glandular content of pancreatic enzymes. J Lab Clin Med 125: 634–640

    PubMed  Google Scholar 

  • Axon ATR, Classen M, Cotton PB et al. (1984) Pancreatography in Chronic Pancreatitis: International Definitions. Gut 25: 1107–1109

    PubMed  Google Scholar 

  • Bachem MG, Schneider E, Gross H et al. (1998) Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 115: 421–432

    PubMed  Google Scholar 

  • Baghurst PA, McMichael AJ, Slavotinek AH, Baghurst KI, Boyle P, Walker AM (1991) A case-control study of diet and cancer of the pancreas. Am J Epidemiol 134: 167–179

    PubMed  Google Scholar 

  • Bagnardi V, Blangiardo M, La Vecchia C, Corrao G (2001) A meta-analysis of alcohol drinking and cancer risk. Br J Cancer 85: 17000–17005

    Article  Google Scholar 

  • Bockman DE, Büchler M, Malfertheiner P, Beger HG (1988) Analysis of nerves in chronic pancreatitis. Gastroentrology 94: 1459–1469

    Google Scholar 

  • Bonelli L, Aste H, Bovo P et al. (2003) Exocrine pancreatic cancer, cigarette smoking, and diabetes mellitus: a case-control study in northern Italy. Pancreas 27: 143–149

    PubMed  Google Scholar 

  • Bouchardy C, Clavel F, La Vecchia C, Raymond L, Boyle P (1990) Alcohol, beer and cancer of the pancreas. Int J Cancer 45: 842–846

    PubMed  Google Scholar 

  • Bradley ED (1982) Pancreatic duct pressure in chronic pancreatitis. Am J Surg 144: 313–316

    Article  PubMed  Google Scholar 

  • Büchler M, Malfertheiner P, Block S et al. (1985) Morphologische und funktionelle Veränderungen des Pankreas nach akuter nekrotisierender Pankreatitis. Z Gastroenterol 2: 79–83

    Google Scholar 

  • Bueno de Mesquita HB, Maisonneuve P, Moerman CJ, Runia S, Boyle P (1992) Lifetime consumption of alcoholic beverages, tea and coffee and exocrine carcinoma of the pancreas: a population-based case-control study in The Netherlands. Int J Cancer 50: 514–522

    PubMed  Google Scholar 

  • Cavallini G, Angelini G, Vantini I et al. (1984) Relationship between morphological (ERP) and functional (secretin-caerulein) infusion test findings in chronic relapsing pancreatitis and following acute pancreatitis. In: Gyr KE, Singer MV, Sarles H (eds) Pancreatitis-Concepts and Classifications. Excerpta Medica, Amsterdam, pp 371–376

    Google Scholar 

  • Chandak GR, Idris MM, Reddy DN, Bhaskar S, Sriram PV, Singh L (2002) Mutations in the pancreatic secretory trypsin inhibitor gene (PSTI/SPINK1) rather than the cationic trypsinogen gene (PRSS1) are significantly associated with tropical calcific pancreatitis. J Med Genet 39: 347–351

    Article  PubMed  Google Scholar 

  • Chari ST, Harder H, Teyssen S, Knodel C, Riepl RL, Singer MV (1996) Effect of beer, yeast-fermented glucose, and ethanol on pancreatic enzyme secretion in healthy human subjects. Dig Dis Sci 6: 1216–1224

    Google Scholar 

  • Chari ST, Singer MV (1994) The Problem of Classification and Staging of Chronic Pancreatitis. Scand J Gastroenterol 29: 949–960

    PubMed  Google Scholar 

  • Chariot J, Roze C, de la Tour J, Souchard M, Hollande E, Vaille C, Debray C (1977) Effects of chronic ethanol consumption on pancreatic response to central vagal stimulation by 2-deoxy-D-glucose in the rat. Digestion 15: 425–437

    PubMed  Google Scholar 

  • Chemtob A, Lévy Ph, Zins M, Bernades P (1995) Influence de l’ancienneté de la pancréatite chronique alcoolique sur la gravité des possées de pancréatite aiguë. Gastroenterol Clin Biol 19: 664–667

    PubMed  Google Scholar 

  • Clavel F, Benhamou E, Auquier A, Tarayre M, Flamant R (1989) Coffee, alcohol, smoking and cancer of the pancreas: a case-control study. Int J Cancer 43: 17–21

    PubMed  Google Scholar 

  • Cohn JA, Friedman KJ, Noone PG, Knowles MR, Silverman LM, Jowell PS (1998) Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis. N Engl J Med 339: 653–658

    PubMed  Google Scholar 

  • Cronin KA, Weed DL, Connor RJ, Prorok PC (1998) Case-control studies of cancer screening: theory and practice. J Natl Cancer Inst 90: 498–504

    Article  PubMed  Google Scholar 

  • Cuzick J, Babiker AG (1989) Pancreatic cancer, alcohol, diabetes mellitus and gall-bladder disease. Int J Cancer 43: 415–421

    PubMed  Google Scholar 

  • Dancour A, Lévy Ph, Milan FCH, Bernades P (1993) Histoire naturelle de la pancréatite chronique alcoolique. Gastroenterol Clin Biol 17: 915–924

    PubMed  Google Scholar 

  • Devaux MA, Lechêne de la Porte P, Johnson C, Sarles H (1990) Structural and functional effects of long-term alcohol administration on the dog exocrine pancreas submitted by two different diets. Pancreas 5: 200–209

    PubMed  Google Scholar 

  • Diem P (2002) Pathogenesis and treatment of diabetes secondary to chronic pancreatitis. In: Büchler MW, Friess H, Uhl W, Malfertheiner P (eds) Chronic pancreatitis. Blackwell, Berlin, pp 355–358

    Google Scholar 

  • Durbec JP, Chevillotte G, Bidart JM, Berthezene P, Sarles H (1983) Diet, alcohol, tobacco and risk of cancer of the pancreas: a case-control study. Br J Cancer 47: 463–470

    PubMed  Google Scholar 

  • Durbec JP, Sarles H (1978) Multicenter survey of the aetiology of pancreatic diseases, relationship between the relative risk of developing chronic pancreatitis and alcohol, protein and lipid consumption. Digestion 18: 337–350

    PubMed  Google Scholar 

  • Dürr H-K (1985) Funktionseinbußen nach akuter nekrotisierender Pankreatitis? Editorial Z Gastroenterologie 23: 84–86

    Google Scholar 

  • Ebbehoj N, Borly L, Bulow J, Rasmussen SG, Madsen P, Matzen P et al. (1990) Pancreatic tissue fluid pressure in chronic pancreatitis. Relation to pain, morphology, and function. Scand J Gastroenterol 25: 1046–1051

    PubMed  Google Scholar 

  • Etemad B, Whitcomb DC (2001) Chronic pancreatitis: diagnosis, classification, and new genetic developments. Gastroenterology 120: 682–707

    PubMed  Google Scholar 

  • Falk RT, Pickle LW, Fontham ET, Correa P, Fraumeni JF Jr (1988) Lifestyle risk factors for pancreatic cancer in Louisiana: a case-control study. Am J Epidemiol 128: 324–336

    PubMed  Google Scholar 

  • Farrow DC, Davis S (1990) Risk of pancreatic cancer in relation to medical history and the use of tobacco, alcohol and coffee. Int J Cancer 45: 816–820

    PubMed  Google Scholar 

  • Fornes NS, Stringhini ML, Elias BM (2003) Reproducibility and validity of a food-frequency questionnaire for use among low-income Brazilian workers. Public Health Nutr 6: 821–827

    Article  PubMed  Google Scholar 

  • Friedman GD, van den Eeden SK (1993) Risk factors for pancreatic cancer: an exploratory study. Int J Epidemiol 22: 30–37

    PubMed  Google Scholar 

  • Ghadirian P, Lynch HT, Krewski D (2003) Epidemiology of pancreatic cancer: an overview. Cancer Detect Prev 27: 87–93

    Article  PubMed  Google Scholar 

  • Grattagliano I, Palmieri V, Vendemiale G, Portincasa P, Altomare E, Palasciano G (1999) Chronic ethanol administration induces oxidative alterations and functional impairment of pancreatic mitochondria in the rat. Digestion 60: 549–553

    Article  PubMed  Google Scholar 

  • Gullo L, Barbara L, Labo G (1988) Effect of cessation of alcohol use on the course of pancreatic dysfunction in alcoholic pancreatitis. Gastroenterology 95: 1063–1968

    PubMed  Google Scholar 

  • Gullo L, Durbec JP (1984) Epidemiology and etiology of pancreatitis. Summary. In: Gyr KE, Singer MV, Sarles H (eds) Pancreatitis — concepts and classifications. Excerpta Medica, Amsterdam, pp 371–376

    Google Scholar 

  • Gullo L, Pezzilli R, Morselli-Labate AM (1995) Coffee and cancer of the pancreas: an Italian multicenter study. The Italian Pancreatic Cancer Study Group. Pancreas 11: 223–229

    PubMed  Google Scholar 

  • Hajnal F, Flores M, Radley S, Valenzuela JE (1990) Effect of alcohol and alcoholic beverages on meal-stimulated pancreatic secretion in humans. Gastroenterology 98: 191–196

    PubMed  Google Scholar 

  • Hajnal F, Flores MC, Valenzuela JE (1989) Effect of alcohol and alcoholic beverages on nonstimulated pancreatic secretion in humans. Pancreas 4: 486–491

    PubMed  Google Scholar 

  • Hajnal F, Flores MC, Valenzuela JE (1993) Pancreatic secretion in chronic alcoholics. Effects of acute alcohol or wine on response to a meal. Dig Dis Sci 38: 12–17

    Article  PubMed  Google Scholar 

  • Hanck C, Schneider A, Whitcomb DC (2003) Genetic polymorphisms in alcoholic pancreatitis. Best Pract Res Clin Gastroenterol 17: 613–623

    Article  PubMed  Google Scholar 

  • Hanck Ch, Singer MV (1997) Does acute alcoholic pancreatitis exist without preexisting chronic pancreatitis? Scand J Gastroenterol 32: 625–626

    PubMed  Google Scholar 

  • Harnack LJ, Anderson KE, Zheng W, Folsom AR, Sellers TA, Kushi LH (1997) Smoking, alcohol, coffee, and tea intake and incidence of cancer of the exocrine pancreas: the Iowa Women’s Health Study. Cancer Epidemiol Biomarkers Prev 6: 1081–1086

    PubMed  Google Scholar 

  • Hayakawa T, Kondo T, Shibata T, Sugimoto Y, Kitagawa M (1989) Chronic alcoholism and evolution of pain and prognosis in chronic pancreatitis. Dig Dis Science 34: 33–38

    Article  Google Scholar 

  • Heuch I, Kvale G, Jacobsen BK, Bjelke E (1983) Use of alcohol, tobacco and coffee, and risk of pancreatic cancer. Br J Cancer 48: 637–643

    PubMed  Google Scholar 

  • Howe GR, Burch JD (1996) Nutrition and pancreatic cancer. Cancer Causes Control 7: 69–82

    Article  PubMed  Google Scholar 

  • International Agency for Resarch on Cancer (IARC) (1988) Alcohol drinking. IARC monograph on the evaluation of carcinogenic risks to humans, vol 44. IARC, Lyon, pp 155–158

    Google Scholar 

  • Jain M, Howe GR, St Louis P, Miller AB (1991) Coffee and alcohol as determinants of risk of pancreas cancer: a case-control study from Toronto. Int J Cancer 47: 384–389

    PubMed  Google Scholar 

  • Ji BT, Chow WH, Dai Q et al. (1995) Cigarette smoking and alcohol consumption and the risk of pancreatic cancer: a case-control study in Shanghai, China. Cancer Causes Control 6: 369–376

    Article  PubMed  Google Scholar 

  • Jian R, Cortot A, Ducrot F, Jobin G, Chayvialle JA, Modigliani R (1986) Effect of ethanol ingestion on postprandial gastric emptying and secretion, biliopancreatic secretions, and duodenal absorption in man. Dig Dis Sci 31: 604–614

    Article  PubMed  Google Scholar 

  • Kalapothaki V, Tzonou A, Hsieh CC, Toupadaki N, Karakatsani A, Trichopoulos D (1993) Tobacco, ethanol, coffee, pancreatitis, diabetes mellitus, and cholelithiasis as risk factors for pancreatic carcinoma. Cancer Causes Control 4: 375–382

    Article  PubMed  Google Scholar 

  • Klöppel G, Maillet B (1992) The morphological basis for the evolution of acute pancreatitis into chronic pancreatitis. Virchows Arch 420: 1–4

    Article  Google Scholar 

  • Kölbel CBM, Singer MV, Dorsch W, Krege P, Eysselein VE, Layer P, Geobell H (1988) Pancreatic and gastric responses to gastric versus jejunal beer in humans. Pancreas 3: 89–94

    PubMed  Google Scholar 

  • Laugier R, Sarles H (1977) Effets de la consommation chronique d’alcool sur la sécrétion pancréatique exocrine du rat. Variations en fonction de la durée de consommation. Gastroenterol Clin Biol 1: 767–774

    PubMed  Google Scholar 

  • Layer P, Yamamoto H, Kalthoff L, Clain JE, Bakken LJ, DiMagno EP (1994) The different courses of early and late-onset idiopathic and alcoholic chronic pancreatitis. Gastroenterology 107: 1481–1487

    PubMed  Google Scholar 

  • Lee CT, Chang FY, Lee SD (1996) Risk factors for pancreatic cancer in orientals. J Gastroenterol Hepatol 11: 491–495

    PubMed  Google Scholar 

  • Lewitt NS, Adams G, Salmon J et al. (1995) The prevalence and severity of microvascular complications in pancreatic diabetes and IDDM. Diabetes Care 18: 971–974

    PubMed  Google Scholar 

  • Lin Y, Tamakoshi A, Kawamura T et al. (2002b) Risk of pancreatic cancer in relation to alcohol drinking, coffee consumption and medial history: findings from the Japan collaborative cohort study for evaluation of cancer risk. Int J Cancer 99: 742–746

    Article  PubMed  Google Scholar 

  • Lin Y, Tamakoshi A, Kawamura T, Inaba Y, Kikuchi S, Motohashi Y, Kurosawa M; JACC Study Group. Japan Collaborative Cohort (2002a) A prospective cohort study of cigarette smoking and pancreatic cancer in Japan. Cancer Causes Control 13: 249–254

    Article  PubMed  Google Scholar 

  • Löhr M (2000) Pankreas. Gutachterliche Stellungnahme. In: Hahn HG, Riemann JF (Hrsg) Klinische Gastroenterologie, 3. Aufl. Thieme, S 1216–1223

    Google Scholar 

  • Lowenfels AB, Maisonneuve P, Cavallini G et al. (1993) Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. N Engl J Med 328: 1433–1437

    Article  PubMed  Google Scholar 

  • Lyon JL, Mahoney AW, French TK, Moser R Jr (1992) Coffee consumption and the risk of cancer of the exocrine pancreas: a case-control study in a low-risk population. Epidemiology 3: 164–170

    PubMed  Google Scholar 

  • Maisonneuve P, Lowenfels AB (2002) Chronic pancreatitis and pancreatic cancer. Dig Dis 20: 32–37

    PubMed  Google Scholar 

  • Malka D, Hammel P, Maire F et al. (2002) Risk of pancreatic adenocarcinoma in chronic pancreatitis. Gut 51: 849–852

    Article  PubMed  Google Scholar 

  • Mews P, Phillips P, Fahmy R, Korsten MA, Pirola RC, Wilson JS, Apte MV (2002) Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis. Gut 50: 535–541

    Article  PubMed  Google Scholar 

  • Michaud DS, Giovannucci E, Willett WC, Colditz GA, Fuchs CS (2001) Coffee and alcohol consumption and the risk of pancreatic cancer in two prospective United States cohorts. Cancer Epidemiol Biomarkers Prev 10: 429–437

    PubMed  Google Scholar 

  • Mizuno S, Watanabe S, Nakamura K et al. (1992) A multi-institute case-control study on the risk factors of developing pancreatic cancer. Jpn J Clin Oncol 22: 286–291

    PubMed  Google Scholar 

  • Mössner J, Keim V, Niederau C, Büchler M, Singer MV, Lankisch PG, Göke B (1998) Leitlinien zur Therapie der chronischen Pankreatitis. Z Gastroenterol 36: 359–367

    PubMed  Google Scholar 

  • Mulder I, Hoogenveen RT, van Genugten ML, Lankisch PG, Lowenfels AB, de Hollander AE, Bueno-de-Mesquita HB (2002) Smoking cessation would substantially reduce the future incidence of pancreatic cancer in the European Union. Eur J Gastroenterol Hepatol 14: 1343–1353

    Article  PubMed  Google Scholar 

  • Nakamura T, Okabayashi Y, Fujii M, Tani S, Fujisawa T, Otsuki M (1991) Effect of ethanol on pancreatic exocrine secretion in rats. Pancreas 6: 571–577

    PubMed  Google Scholar 

  • Niebergall-Roth E, Harder H, Singer MV (1998) A review: acute and chronic effects of ethanol and alcoholic beverages on the pancreatic exocrine secretion in vivo and in vitro. Alcohol Clin Exp Res 22: 1570–1583

    PubMed  Google Scholar 

  • Nilsen TI, Vatten LJ (2000) A prospective study of lifestyle factors and the risk of pancreatic cancer in Nord-Trondelag, Norway. Cancer Causes Control 11: 645–652

    Article  PubMed  Google Scholar 

  • Olsen GW, Mandel JS, Gibson RW, Wattenberg LW, Schuman LM (1989) A case-control study of pancreatic cancer and cigarettes, alcohol, coffee and diet. Am J Public Health 79: 1016–1019

    PubMed  Google Scholar 

  • Patel AG, Toyama MT, Alvarez C, Nguyen TN, Reber PU, Ashley SW et al. (1995) Pancreatic interstitial pH in human and feline chronic pancreatitis. Gastroenterology 109: 1639–1645

    Article  PubMed  Google Scholar 

  • Perec CJ, Celener D, Tiscornia OM, Baratti C (1979) Effects of chronic ethanol administration on the autonomic innervation of salivary glands, pancreas and heart. Am J Gastroenterol 72: 46–59

    PubMed  Google Scholar 

  • Pfützer RH, Barmada MM, Brunskill AP et al. (2000) SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis. Gastroenterology 119: 615–623

    PubMed  Google Scholar 

  • Planche NE, Palasciano G, Meullenet J, Laugier R, Sarles H (1982) Effect of intravenous alcohol on pancreatic and biliary secretion in man. Dig Dis Sci 27: 449–453

    Article  PubMed  Google Scholar 

  • Ponnappa BC, Hoek JB, Jubinski L, Rubin E (1990) Ethanol withdrawal stimulates protein synthesis in rat pancreatic lobules. Biochem Biophys Acta 1036: 107–112

    PubMed  Google Scholar 

  • Rehm J, Greenfield TK, Walsh G, Xie X, Robson L, Single E (1999) Assessment methods for alcohol consumption, prevalence of high risk drinking and harm: a sensitivity analysis. Int J Epidemiol 28: 219–224

    Article  PubMed  Google Scholar 

  • Rinderknecht H, Stace NH, Renner IG (1985) Effects of chronic alcohol abuse on exocrine pancreatic secretion in man. Dig Dis Sci 30: 65–71

    Article  PubMed  Google Scholar 

  • Sahel J, Sarles H (1979) Modifications of pure human pancreatic juice induced by chronic alcohol consumption. Dig Dis Sci 24: 897–905

    Article  PubMed  Google Scholar 

  • Saluja AK, Lu L, Yamaguchi Y, Hofbauer B, Rünzi M, Dawra R, Bhatia M, Steer ML (1997) A cholecystokinin-releasing factor mediates ethanol-induced stimulation of rat pancreatic secretion. J Clin Invest 99: 506–512

    PubMed  Google Scholar 

  • Sarles H (1986) Chronic pancreatitis: Etiology and pathophysiology. In: Go VLW (ed) The exocrine pancreas: Biology, pathobiology, and diseases. Raven, New York, pp 527–540

    Google Scholar 

  • Sarles H (1991) The geographical distribution of chronic pancreatitis. In: Johnson CD, Imrie CW (eds) Pancreatic disease. Progress and prospects. Springer, Berlin Heidelberg New York Tokyo, pp 177–184

    Google Scholar 

  • Sarles H, Figarella C, Clemente F (1971) The interaction of ethanol, dietary lipids, and proteins on the rat pancreas. Digestion 4: 12–22

    Google Scholar 

  • Sarles H, Sarles JC, Camatte R (1965) Observations on 205 confirmed cases of acute pancreatitis, recurring pancreatitis, and chronic pancreatitis. Gut 6: 545–559

    PubMed  Google Scholar 

  • Schmidt DN, Devaux M-A, Biedzinski TM, Sarles H (1983) Cholinergic stimulation and inhibition of pancreatic secretion in alcohol-adapted dogs. Scand J Gastroenterol 18: 425–431

    PubMed  Google Scholar 

  • Schmidt DN, Pandol SJ (1990) Differing effects of ethanol on in vitro stimulated pancreatic enzyme secretion in ethanol-fed and control rats. Pancreas 5: 27–36

    PubMed  Google Scholar 

  • Schneider A, Pfützer RH, Barmada MM, Slivka A, Martin J, Whitcomb DC (2003) Limited contribution of the SPINK1 N34S mutation to the risk and severity of alcoholic chronic pancreatitis: a report from the United States. Dig Dis Sci 48: 1110–1115

    Article  PubMed  Google Scholar 

  • Schneider A, Suman A, Rossi L et al. (2002) SPINK1/PSTI mutations are associated with tropical pancreatitis and type II diabetes mellitus in Bangladesh. Gastroenterology 123: 1026–1030

    Article  PubMed  Google Scholar 

  • Schneider A, Whitcomb DC (2002) Hereditary pancreatitis: a model for inflammatory diseases of the pancreas. Best Pract Res Clin Gastroenterol 16: 347–363

    Article  PubMed  Google Scholar 

  • Schneider A, Whitcomb DC, Singer MV (2002) Animal models in alcoholic pancreatitis — what can we learn? Pancreatology 2: 189–203

    Article  PubMed  Google Scholar 

  • Sharer N, Schwarz M, Malone G, Howarth A, Painter J, Super M, Braganza J (1998) Mutations in the cystic fibrosis gene in patients with chronic pancreatitis. N Engl J Med 339: 645–652

    PubMed  Google Scholar 

  • Shu XO, Yang G, Jin F et al. (2004) Validity and reproducibility of the food frequency questionnaire used in the Shanghai Women’s Health Study. Eur J Clin Nutr 58: 17–23

    Article  PubMed  Google Scholar 

  • Siegmund E, Pommerenke H, Jonas L, Nizze H, Hollerich I, Rohring A, Schuff-Werner P (2000) Inositol 1,4,5-trisphosphate formation, cytoplasmic calcium dynamics, and alpha-amylase secretion of pancreatic acini isolated from aged and chronically alcohol-fed rats. Int J Pancreatol 27: 39–50

    PubMed  Google Scholar 

  • Silverman DT, Brown LM, Hoover RN et al. (1995) Alcohol and pancreatic cancer in blacks and whites in the United States. Cancer Res 55: 4899–4905

    PubMed  Google Scholar 

  • Singer MV, Chari ST (1998) Classification of chronic pancreatitis. In: Beger HG, Warshaw AL, Büchler MW, Carr-Locke DL, Neoptolemos JP, Russel C, Saar MG (eds) The pancreas. Blackwell Science, Oxford, pp 668–671

    Google Scholar 

  • Singer MV, Gyr K, Sarles H (1985) Revised Classification of Pancreatitis. Gastroenterology 89: 683–690

    PubMed  Google Scholar 

  • Singer MV, Müller MK (1995) Epidemiologie, Ätiologie und Pathogenese der chronischen Pankreatitis. In: Mössner J, Adler G, Fölsch UR, Singer MV (Hrsg) Erkrankungen des exkretorischen Pankreas. Fischer, Jena Stuttgart, S 313–324

    Google Scholar 

  • Singer MV, Teyssen S, Eysselein VE (1991) Action of beer and its ingredients on gastric acid secretion and release of gastrin in humans. Gastroenterology 101: 935–942

    PubMed  Google Scholar 

  • Singh M (1987) Alcoholic pancreatitis in rats fed ethanol in a nutritionally adequate liquid diet. Int J Pancreatol 2: 311–324

    PubMed  Google Scholar 

  • Singh M, Simsek H (1990) Ethanol and the pancreas. Current status. Gastroenterology 98: 1051–1062

    PubMed  Google Scholar 

  • Skinazi F, Lévy Ph, P Bernades (1995) Les pancréatites aiguës alcooliques révèlent-elles toujours une pancréatite chronique? Gastroenterol Clin Biol 19: 266–269

    PubMed  Google Scholar 

  • Soler M, Chatenoud L, La Vecchia C, Franceschi S, Negri E (1998) Diet, alcohol, coffee and pancreatic cancer: final results from an Italian study. Eur J Cancer Prev 7: 455–460

    PubMed  Google Scholar 

  • Strum WB (1995) Abstinence in alcoholic chronic pancreatitis. Effect on pain and outcome. J Clin Gastroenterol 20: 37–41

    PubMed  Google Scholar 

  • Tachibana I, Okabayashi Y, Akiyama T, Koide M, Masushita K, Otsuki M (1996) Ethanol inhibits CCK-induced enzyme secretion by affecting calcium pump activity in solated rat pancreatic acini. Pancreas 13: 316–323

    PubMed  Google Scholar 

  • Tavani A, Pregnolato A, Negri E, La Vecchia C (1997) Alcohol consumption and risk of pancreatic cancer. Nutr Cancer 27: 157–161

    PubMed  Google Scholar 

  • Teich N, Mössner J, Keim V (1999) Screening for mutations in the cationic trypsinogen gene: are they of relevance in chronic alcoholic pancreatitis? Gut 44: 413–416

    PubMed  Google Scholar 

  • Tiscornia OM, Palasciano G, Sarles H (1974) Pancreatic changes induced by chronic (two years) ethanol treatment in the dog. Gut 15: 893

    Google Scholar 

  • Tsai J-H, Kobari M, Takeda K, Miyashita E, Rahman MM, Matsuno S (1991) Changes of duodenal pH and pancreatic exocrine function after upper GI intraluminal ethanol administration. Tohoku J Exp Med 164: 81–91

    PubMed  Google Scholar 

  • Vaccaro MI, Tiscornia OM, Calvo EL, Cresta MA, Celener D (1992) Effect of ethanol intake on pancreatic exocrine secretion in mice. Scand J Gastroenterol 27: 783–786

    PubMed  Google Scholar 

  • Van Gossum A, Closset P, Noel E, Cremer M, Neve J (1996) Deficiency in antioxidant factors in patients with alcohol-related chronic pancreatitis. Dig Dis Sci 41: 1225–1231

    PubMed  Google Scholar 

  • Whitcomb DC, Gorry MC, Preston RA et al. (1996) Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 14: 141–145

    PubMed  Google Scholar 

  • Witt H, Luck W, Becker M et al. (2001) Mutation in the SPINK1 trypsin inhibitor gene, alcohol abuse, and chronic pancreatitis. JAMA 285: 2716–2717

    Article  Google Scholar 

  • Witt H, Luck W, Hennies HC et al. (2000) Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet 25: 213–216

    PubMed  Google Scholar 

  • World Cancer Research Fund, American Institute for Cancer Research (1997) Food, nutrition and the prevention of cancer: a global perspective. American Institute for Cancer Research, Washington, DC

    Google Scholar 

  • Yamamoto A, Ishiguro H, Ko SB et al. (2003) Ethanol induces fluid hypersecretion from guinea-pig pancreatic duct cells. J Phyiol 551: 917–926

    Article  Google Scholar 

  • Ye W, Lagergren J, Weiderpass E, Nyren O, Adami HO, Ekbom A (2002) Alcohol abuse and the risk of pancreatic cancer. Gut 51: 236–239

    Article  PubMed  Google Scholar 

  • Zatonski WA, Boyle P, Przewozniak K, Maisonneuve P, Drosik K, Walker AM (1993) Cigarette smoking, alcohol, tea and coffee consumption and pancreas cancer risk: a case-control study from Opole, Poland. Int J Cancer 53: 601–607

    PubMed  Google Scholar 

  • Zheng W, McLaughlin JK, Gridley G et al. (1993) A cohort study of smoking, alcohol consumption, and dietary factors for pancreatic cancer (United States). Cancer Causes Control 4: 477–482

    Article  PubMed  Google Scholar 

  • Zondervan KT, Cardon LR, Kennedy SH (2002) What makes a good case-control study? Design issues for complex traits such as endometriosis. Hum Reprod 17: 1415–1423

    Article  PubMed  Google Scholar 

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© 2005 Springer Medizin Verlag Heidelberg

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(2005). Alkohol und Pankreas. In: Singer, M.V., Teyssen, S. (eds) Alkohol und Alkoholfolgekrankheiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26446-9_19

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  • DOI: https://doi.org/10.1007/3-540-26446-9_19

  • Publisher Name: Springer, Berlin, Heidelberg

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