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Imaging of cerebral blood flow and metabolism in brain injury in the ICU

  • Conference paper
Intracranial Pressure and Brain Monitoring XII

Part of the book series: Acta Neurochirurgica Supplementum ((NEUROCHIRURGICA,volume 95))

Summary

The heterogeneity of the initial insult and subsequent pathophysiology has made both the study of human head injury and design of randomised controlled trials exceptionally difficult. The combination of multimodality bedside monitoring and functional brain imaging positron emission tomography (PET) and magnetic resonance (MR), incorporated within a Neurosciences Critical Care Unit, provides the resource required to study critically ill patients after brain injury from initial ictus through recovery from coma and rehabilitation to final outcome. Methods to define cerebral ischemia in the context of altered cerebral oxidative metabolism have been developed, traditional therapies for intracranial hypertension re-evaluated and bedside monitors cross-validated. New modelling and analytical approaches have been developed.

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Author information

Authors and Affiliations

  1. Wolfson Brain Imaging Centre, University of Cambridge, Addenbrookes Hospital, Cambridge, UK

    J. D. Pickard, P. J. Hutchinson, J. P. Coles, L. A. Steiner, A. J. Johnston, T. D. Fryer, M. R. Coleman, P. Smielewski, D. A. Chatfield, F. Aigbirhio, G. B. Williams, J. C. Clark, C. H. Salmond, P. G. Bradley, T. A. Carpenter, R. Salvador, A. Pena, J. H. Gillard, A. S. Cunningham, S. Piechnik & D. K. Menon

  2. Academic Neurosurgery Unit, University of Cambridge, Addenbrookes Hospital, Box 167, Cambridge, CB22QQ, UK

    J. D. Pickard, P. J. Hutchinson, L. A. Steiner, M. R. Coleman, P. Smielewski, A. Pena, S. Piechnik & M. Czosnyka

  3. Academic Anaesthesia Unit, University of Cambridge, Addenbrookes Hospital, Cambridge, UK

    J. P. Coles, A. J. Johnston, D. A. Chatfield, P. G. Bradley, A. S. Cunningham & D. K. Menon

  4. MRC Biostatistics Unit, University of Cambridge, Addenbrookes Hospital, Cambridge, UK

    K. Rice, C. H. Salmond & B. J. Sahakian

  5. Academic Radiology Unit, University of Cambridge, Addenbrookes Hospital, Cambridge, UK

    J. H. Gillard

Authors
  1. J. D. Pickard
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  2. P. J. Hutchinson
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  3. J. P. Coles
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  4. L. A. Steiner
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  5. A. J. Johnston
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  6. T. D. Fryer
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  7. M. R. Coleman
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  8. P. Smielewski
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  9. D. A. Chatfield
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  10. F. Aigbirhio
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  11. G. B. Williams
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  12. K. Rice
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  13. J. C. Clark
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  14. C. H. Salmond
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  15. B. J. Sahakian
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  16. P. G. Bradley
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  17. T. A. Carpenter
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  18. R. Salvador
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  19. A. Pena
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  20. J. H. Gillard
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  21. A. S. Cunningham
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  22. S. Piechnik
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  23. M. Czosnyka
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  24. D. K. Menon
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Corresponding author

Correspondence to J. D. Pickard .

Editor information

Editors and Affiliations

  1. Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China

    Wai S. Poon , Matthew T. V. Chan , Keith Y. C. Goh , Joseph M. K. Lam  & Stephanie C. P. Ng , , ,  & 

  2. Medical College of Virginia Commonwealth University, Virginia, USA

    Anthony Marmarou

  3. Academisch Ziekenhuis Dijkzigt, Erasmus University Rotterdam, Rotterdam, The Netherlands

    Cees J. J. Avezaat

  4. Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK

    John D. Pickard , Marek Czosnyka  & Peter J. A. Hutchinson ,  & 

  5. School of Medicine, Nihon University, Tokyo, Japan

    Yoichi Katayama

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© 2005 Springer-Verlag

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Pickard, J.D. et al. (2005). Imaging of cerebral blood flow and metabolism in brain injury in the ICU. In: Poon, W.S., et al. Intracranial Pressure and Brain Monitoring XII. Acta Neurochirurgica Supplementum, vol 95. Springer, Vienna. https://doi.org/10.1007/3-211-32318-X_94

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  • DOI: https://doi.org/10.1007/3-211-32318-X_94

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-24336-7

  • Online ISBN: 978-3-211-32318-2

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