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Advanced Peripheral Nerve Surgery and Minimal Invasive Spinal Surgery pp 87–92Cite as

CT-guided oxygen-ozone treatment for first degree spondylolisthesis and spondylolysis

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Part of the book series: Acta Neurochirurgica ((NEUROCHIRURGICA,volume 97))

Summary

Aim of this study was to assess the therapeutic outcome of CT- guided periganglionic infiltration of oxygen-ozone and injection of the gas mixture into the lysis points in patients with first grade spondylolisthesis and spondylolysis. We selected 18 patients presenting with low back pain and sciatica resistant to physical and medical management with a radiological diagnosis of spondylolis-thesis and spondylolysis subsequently confirmed on CT scan. Following CT-guided bilateral periganglionic O2–O3 infiltration and injection into the lysis points, 15 patients (83.3%) obtained a complete remission of pain. None of the patients reported pain recurrence at clinical follow-up visits one, three and six months after treatment.

Oxygen-ozone therapy administered in this way is even more effective than CT-guided periganglionic infiltration alone as it has an additional anti-inflammatory and analgesic effect on the nerve structures in the neural arch, namely Luschka’s recurrent nerve.

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References

  1. Al-Sebai MW, Al-Khawashki H (1999) Spondyloptosis and multiple-level spondylolysis. European Spine Journal 8(1): 75–77

    Article  PubMed  Google Scholar 

  2. Andreula C (2002) Ernie discali lombosacrali: tecnica di chemiodiscolisi con nucleoptesi con 02-03 e infiltrazione periradicolare e periganglionare sotto guida TC Rivista Italiana di Ossigeno-Ozono Terapia 1: 79–85

    Google Scholar 

  3. Baksi DP (1998) Sacrospinalis muscle-pedicle bone graft in posterolateral fusion for spondylolisthesis. International Ortho-paedics 22(4): 234–240

    Google Scholar 

  4. Bernicker JP, Kohl HW, 3rd. Sahni I, Esses SI (1999) Long-term functional and radiographic follow-up of surgically treated isthmic spondylolisthesis. American Journal of Orthopedics (Chatham, NJ) 28(11): 631–636

    PubMed  Google Scholar 

  5. Bocci V, Luzzi E, Corradeschi F et al (1993) Studies on the biological effect of ozone: 4, Cytokine production and glutathione levels in human erythrocytes. J Biol Regular Homeost Agent 7:133–138

    Google Scholar 

  6. Bocci V (1996) Does ozone therapy normalize the cellular redox balance? Med Hypotheses 46: 150–154

    PubMed  Google Scholar 

  7. Bocci V (1997) Ozone as a bioregulator. Pharmacology and toxicology of ozonotherapy today. J Biol Reg Homeo Agents 10: 31–53

    Google Scholar 

  8. Bocci V, Lucci E, Coradeschi F, Paulesu C (1994) Studies on the biological effects of ozone: 5. Evaluation of immunological parameters and tolerability in normal volunteers receiving ambulatory autohaemotherapy. Biotherapy 7: 83–90

    Google Scholar 

  9. Bonetti M (2002) Tecnica intraforaminale TC guidata. Rivista Italiana di Ossigeno-Ozono Terapia 1: 69–72

    Google Scholar 

  10. Booth KC, Bridwell KH, Eisenberg BA, Baldus CR, Lenke LG (1999) Minimum 5-year results of degenerative spondylolisthesis treated with decompression and instrumented posterior fusion. Spine 24(16): 1721–1727

    PubMed  Google Scholar 

  11. Cinotti G, Postacchini F, Fassari F, Urso S (1997) Predisposing factors in degenerative spondylolisthesis. A radiographic and CT study. International Orthopaedics 21(5): 337–342

    PubMed  Google Scholar 

  12. Fabris G (2002) Tecnica Intraforaminale con guida fluoroscopica. Rivista Italiana di Ossigeno-Ozono Terapia 1: 63–68

    Google Scholar 

  13. Fabris G, Tomassini G, Petralia B, Lavaroni A, De Nardi F, De Luca G, Biasizzo E, Laiza F (2001) L’ossigeno terapia intraforaminale. Rivista di Neuroradiologia 14[Suppl 1]: 25–30

    Google Scholar 

  14. Ghosez JP, Himmer O, Devyver B, Rossillon R, Beugnies A, Lootvoet L (1992) Surgical treatment of isthmic spondylolis-thesis. A comparative study of 3 types of arthrodesis. Revue de Chirurgie Orthopedique et Reparatrice de 1 Appareil Moteur 78(8): 515–528

    Google Scholar 

  15. Hilibrand AS, Rand N (1999) Degenerative lumbar stenosis: diagnosis and management. Journal of the American Academy of Orthopaedic Surge-ons 7(4): 239–249

    Google Scholar 

  16. Iliakis E, Valadakis V, Vynios DH, Tsiganos CP, Agapitos E (2001) Rationalization of the activity of medical ozone on intervertebral disc and histological and biochemical study. Rivista di Neuroradiologia 14[Suppl 1]: 25–30

    Google Scholar 

  17. Jinkins JR (1995) The pathoanatomic basis of somatic, autonomic and neurogenic syndromes originating in the lumbosacral spine. Rivista di Neuroradiologia 8[Suppl 1]: 35–51

    Google Scholar 

  18. Kim NH, Lee JW (1999) Anterior interbody fusion versus post-erolateral fusion with transpedicular fixation for isthmic spondylolisthesis in adults. A comparison of clinical results. Spine 24(8): 812–816; discussion 817

    PubMed  Google Scholar 

  19. Meyerding HW (1931) Spondylolisthesis. J Bone Joint Surg 13(A): 39–48

    Google Scholar 

  20. Mochida J, Suzuki K, Chiba M (1999) How to stabilize a single level lesion of degenerative lumbar spondylolisthesis. Clinical Orthopaedics & Related Research (368): 126–134

    Google Scholar 

  21. O’Sullivan PB, Phyty GD, Twomey LT, Allison GT (1997) Evaluation of specific stabilizing exercise in the treatment of chronic low back pain with radiologic diagnosis of spondylolysis or spondylolisthesis. Spine 22(24): 2959–2967

    PubMed  Google Scholar 

  22. Roca J, Ubierna MT, Caceres E, Iborra M (1999) One-stage decompression and posterolateral and interbody fusion for severe spondylolisthesis. An analysis of 14 patients. Spine 24(7):709–714

    PubMed  Google Scholar 

  23. Rothman SL, Glenn WV Jr (1984) CT multiplanar reconstruction in 253 cases of lumbar spondylolysis. AJNR Am J Neuroradiol 5: 81–90

    PubMed  Google Scholar 

  24. Teplick JG, Laffey PA, Berman A, Haskin ME (1986) Diagnosis and evaluation of spondylolisthesis and/or spondylolysis on axial CT. AJNR Am J Neuroradiol 7: 479 491

    PubMed  Google Scholar 

  25. Theiss SM (2001) Isthmic spondylolisthesis and spondylolysis. J South Orthop Assoc Fall 10(3): 164–172

    Google Scholar 

  26. Ulmer JL, Mathews VP, Elster AD, King JC (1995) Lumbar spondylolysis without spondylolisthesis: recognition of isolated posterior element subluxation on sagittal MR. AJNR Am J Neuroradiol 16: 1393–1398

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Servizio di Neuroradiologia, Istituto Clinico Città di Brescia, Brescia, Italy

    Dr. Matteo Bonetti & F. Albertini

  2. Servizio di Neuroradiologia, Casa di Cura S. Anna, Brescia, Italy

    A. Fontana

Authors
  1. Dr. Matteo Bonetti
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  2. A. Fontana
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  3. F. Albertini
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Corresponding author

Correspondence to Matteo Bonetti .

Editor information

Editors and Affiliations

  1. EU.N.I. European Neurosurgical Institute, Treviso, Italy

    Alberto Alexandre

  2. Neurosurgical Department, Verona University, Verona, Italy

    Albino Bricolo

  3. Boltzmann Institut für Experimentelle Plastische Chirurgie, University of Vienna, Austria

    Hanno Millesi

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© 2005 Springer-Verlag

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Bonetti, M., Fontana, A., Albertini, F. (2005). CT-guided oxygen-ozone treatment for first degree spondylolisthesis and spondylolysis. In: Alexandre, A., Bricolo, A., Millesi, H. (eds) Advanced Peripheral Nerve Surgery and Minimal Invasive Spinal Surgery. Acta Neurochirurgica, vol 97. Springer, Vienna. https://doi.org/10.1007/3-211-27458-8_19

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  • DOI: https://doi.org/10.1007/3-211-27458-8_19

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-23368-9

  • Online ISBN: 978-3-211-27458-3

  • eBook Packages: MedicineMedicine (R0)

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