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Estrogens and Other Hormones in the Treatment of Premenstrual Syndromes

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Estrogen Effects in Psychiatric Disorders
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Reference

  • American Psychiatric Association (1994) Premenstrual dysphoric disorder. In: Diagnostic and statistical manual of mental disorders, 4th ed. American Psychiatric Association, Washington DC, 715–718

    Google Scholar 

  • Bäckström T, Hansson-Malmström Y, Lindhe B-Ã…, Cavalli-Björkman B, Nordenström S (1992) Oral contraceptives in premenstrual syndrome: a randomized comparison of triphasic and monophasic preparations. Contraception 46: 253–268

    PubMed  Google Scholar 

  • Bancroft J, Rennie D (1993) The impact of oral contraceptives on the experience of perimenstrual mood, clumsiness, food craving and other symptoms. J Psychosom Res 37: 195–202

    Article  PubMed  CAS  Google Scholar 

  • Bancroft J, Sanders D, Warner P, Loudon N (1987) The effects of oral contraceptives on mood and sexuality: a comparison of triphasic and combined preparations. J Psychosom Obstet Gynaecol 7: 1–8

    Google Scholar 

  • Bicikova M, Dibbelt L, Hill M, Hampl R, Starka L (1998) Allopregnanolone in women with premenstrual syndrome. Horm Metab Res 30: 227–30

    PubMed  CAS  Google Scholar 

  • Born L, Steiner M (2001) Current management of premenstrual syndrome and premenstrual dysphoric disorder. Curr Psychiatr Reports 3: 463–469

    CAS  Google Scholar 

  • Brown CS, Ling FW, Andersen RN, Farmer RG, Arheart KL (1994) Efficacy of depot leuprolide in premenstrual syndrome: effect of symptom severity and type in a controlled trial. Obstet Gynecol 84: 779–786

    PubMed  CAS  Google Scholar 

  • Burnet RB, Radden HS, Easterbrook EG, McKinnon RA (1991) Premenstrual syndrome and spironolactone. Aust N Z J Obstet Gynaecol 31: 366–368

    PubMed  CAS  Google Scholar 

  • Casper RF, Hearn MT (1990) The effect of hysterectomy and bilateral oophorectomy in women with severe premenstrual syndrome. Am J Obstet Gynecol 162: 105–109

    PubMed  CAS  Google Scholar 

  • Casson P, Hahn PM, Van Vugt DA, Reid RL (1990) Lasting response to ovariectomy in severe intractable premenstrual syndrome. Am J Obstet Gynecol 162: 99–105

    PubMed  CAS  Google Scholar 

  • Chan AF, Mortola JF, Wood SH, Yen SS (1994) Persistence of premenstrual syndrome during low-dose administration of the progesterone antagonist RU 486. Obstet Gynecol 84: 1001–1005

    PubMed  CAS  Google Scholar 

  • Crammer JL (1986) Premenstrual depression, cortisol and oestradiol treatment. Psychol Med 16: 451–455

    Article  PubMed  CAS  Google Scholar 

  • Dalton K (1990) The aetiology of premenstrual syndrome is with the progesterone receptors. Med Hypotheses 31: 323–327

    Article  PubMed  CAS  Google Scholar 

  • Dennerstein L, Morse C, Gotts G, Brown J, Smith M, Oats J, Burrows G (1986) Treatment of premenstrual syndrome a double-blind trial of dydrogesterone. J Affect Disord 11: 199–205

    Article  PubMed  CAS  Google Scholar 

  • Dennerstein L, Spencer-Gardner C, Gotts G, Brown JB, Smith MA, Burrows GD (1985) Progesterone and the premenstrual syndrome: a double blind crossover trial. Br Med J 290: 1617–1621

    CAS  Google Scholar 

  • Dhar V, Murphy BE (1990) Double-blind randomized crossover trial of luteal phase estrogens (Premarin) in the premenstrual syndrome (PMS). Psychoneuroen-docrinology 15: 489–493

    CAS  Google Scholar 

  • Dhar V, Murphy BE (1991) The premenstrual syndrome and its treatment. J Steroid Biochem Mol Biol 9: 275–281

    Google Scholar 

  • Di Carlo C, Palomba S, Tommaselli GA, Guida M, Di Spiezio Sardo A, Nappi C (2001) Use of leuprolide acetate plus tibolone in the treatment of severe premenstrual syndrome. Fertil Steril 75: 380–384

    PubMed  Google Scholar 

  • Dimmock PW, Wyatt KM, Jones PW, O'Brien PMS (2000) Efficacy of selective serotonin-reuptake inhibitors in premenstrual syndrome: a systematic review. Lancet 356: 1131–1136

    Article  PubMed  CAS  Google Scholar 

  • Endicott J, Amsterdam J, Eriksson E, Frank E, Freeman E, Hirschfeld R, Ling F, Parry B, Pearlstein T, Rosenbaum J, Rubinow D, Schmidt P, Severino S, Steiner M, Stewart DE, Thys-Jacobs S (1999) Is premenstrual dysphoric disorder a distinct clinical entity? J Womens Health Gender-based Med 8: 663–679

    CAS  Google Scholar 

  • Epperson CN, Haga K, Mason GF, Sellers E, Gueorguieva R, Zhang W, Weiss E, Rothman DL, Krystal JH (2002) Cortical γ-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder. Arch Gen Psychiatry 59: 851–858

    PubMed  CAS  Google Scholar 

  • Epperson CN, Wisner KL, Yamamoto B (1999) Gonadal steroids in the treatment of mood disorders. Psychosom Med 61: 676–697

    PubMed  CAS  Google Scholar 

  • Eriksson E, Endicott J, Andersch B, Angst J, Demyttenaere K, Facchinetti F, Lanczik M, Montgomery S, Muscettola G, O'Brien PMS, Studd J, Sundblad C, Young AH (2002) New perspectives on the treatment of premenstrual syndrome and premenstrual dysphoric disorder. Arch Women Ment Health 4: 111–119

    Google Scholar 

  • Eriksson E, Sundblad C, Landén M, Steiner M (2000b) Behavioural effects of androgens in women. In: Steiner M, Yonkers KA, Eriksson E (eds) Mood disorders in women. Martin Dunitz, London, 233–245

    Google Scholar 

  • Eriksson E, Sundblad C, Yonkers KA, Steiner M (2000a) Premenstrual dysphoria and related conditions: symptoms, pathophysiology and treatment. In: Steiner M, Yonkers KA, Eriksson E (eds) Mood disorders in women. Martin Dunitz, London, 269–293

    Google Scholar 

  • Frank R (1931) The hormonal causes of premenstrual tension. Arch Neurol Psychiatry 26: 1053–1057

    Google Scholar 

  • Freeman EW, Frye CA, Rickels K, Martin PA, Smith SS (2002) Allopregnanolone levels and symptom improvement in severe premenstrual syndrome. J Clin Psychopharmacol 22: 516–520

    Article  PubMed  CAS  Google Scholar 

  • Freeman EW, Kroll R, Rapkin A, Pearlstein T, Brown C, Parsey K, Zhang P, Patel H, Foegh M, for the PMS/PMDD Research group (2001b) Evaluation of a unique oral contraceptive in the treatment of premenstrual dysphoric disorder. J Womens Health Gender-based Med 10: 561–569

    CAS  Google Scholar 

  • Freeman EW, Purdy RH, Coutifaris C, Rickels K, Paul SM (1993) Anxiolytic metabolites of progesterone: correlation with mood and performance measures following oral progesterone administration to healthy female volunteers. Neuroendocrinology 58: 478–484

    PubMed  CAS  Google Scholar 

  • Freeman EW, Rickels K, Sondheimer SJ, Polansky M (2001a) Concurrent use of oral contraceptives with antidepressants for premenstrual syndromes. J Clin Psychopharmacol 21: 540–542

    Article  PubMed  CAS  Google Scholar 

  • Freeman EW, Rickels K, Sondheimer SJ, Polansky M (1995) A double-blind trial of oral progesterone, alprazolam, and placebo in treatment of severe premenstrual syndrome. J Am Med Assoc 274: 51–57

    Article  CAS  Google Scholar 

  • Girdler SS, Straneva PA, Light KC, Pedersen CA, Morrow AL (2001) Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder. Biol Psychiatry 49: 788–797

    Article  PubMed  CAS  Google Scholar 

  • Halbreich U, Kahn LS (2001) Role of estrogen in the aetiology and treatment of mood disorders. CNS Drugs 15: 797–817

    PubMed  CAS  Google Scholar 

  • Halbreich U, Kahn LS (2000) Selective oestrogen receptor modulators-current and future brain and behaviour applications. Exp Opin Pharmacother 1: 1385–1398

    CAS  Google Scholar 

  • Hammarbäck S, Bäckström T, Holst J, von Schoultz B, Lyrenas S (1985) Cyclical mood changes as in the premenstrual tension syndrome during sequential estrogen-progestagen postmenopausal replacement therapy. Acta Obstet Gynecol Scand 64: 393–397

    Article  PubMed  Google Scholar 

  • Hammarbäck S, Ekholm UB, Bäckström T (1991) Spontaneous anovulation causing disappearance of cyclical symptoms in women with the premenstrual syndrome. Acta Endocrin (Cophenh) 125: 132–137

    Google Scholar 

  • Henshaw C, Foreman D, Belcher J, Cox J, O'Brien S (1996) Can one induce premenstrual symptomatology in women with prior hysterectomy and bilateral oophorectomy? J Psychosom Obstet Gynecol 17: 21–28

    CAS  Google Scholar 

  • Ho HP, Olsson M, Westberg L, Melke J, Eriksson E (2001) The serotonin reuptake inhibitor fluoxetine reduces sex steroid-related aggression in female rats: an animal model of premenstrual irritability? Neuropsychopharmacology 24: 502–510

    Article  PubMed  CAS  Google Scholar 

  • Kendler KS, Karkowski LM, Corey LA, Neale MC (1998) Longitudinal population-based twin study of retrospectively reported premenstrual symptoms and lifetime major depression. Am J Psychiatry 155: 1234–1240

    PubMed  CAS  Google Scholar 

  • Lyall H, Campbell-Brown M, Walker JJ (1999) GnRH analogue in everyday gynecology: is it possible to rationalize its use? Acta Obstet Gynecol Scand 78: 340–345

    Article  PubMed  CAS  Google Scholar 

  • Magos AL, Brincat M, Studd JW (1986) Treatment of the premenstrual syndrome by subcutaneous oestradiol implants and cyclical oral norethisterone: placebo controlled study. Br Med J 292: 1629–1633

    Article  CAS  Google Scholar 

  • Majewska MD (1992) Neurosteroids: endogenous bimodal modulators of the GABA receptor Mechanism of action and physiological significance. Progr Neurobiol 38: 379–395

    Article  PubMed  CAS  Google Scholar 

  • Marriott A, Faragher EB (1986) An assessment of psychological state associated with the menstrual cycle in users of oral contraception. J Psychosom Res 30: 41–47

    Article  PubMed  CAS  Google Scholar 

  • Mezrow G, Shoupe D, Spicer D, Lobo R, Leung B, Pike M (1994) Depot leuprolide acetate with estrogen and progestin add-back for long-term treatment of premenstrual syndrome. Fertil Steril 62: 932–937

    PubMed  CAS  Google Scholar 

  • Mitwally MFM, Gotlieb L, Casper RF (2002) Prevention of bone loss and hypoes-trogenic symptoms by estrogen and interrupted progestogen add-back in longterm GnRH-agonist down-regulated patients with endometriosis and premenstrual syndrome. Menopause 9: 236–241

    PubMed  Google Scholar 

  • Monteleone P, Luisi S, Tonetti A, Bernardi F, Genazzani AD, Luisi M, Petraglia F, Genazzani AR (2000) Allopregnanolone concentrations and premenstrual syndrome. Eur J Endocrin 142: 269–73.

    Article  CAS  Google Scholar 

  • Muse KN, Cetel NS, Futterman LA, Yen SC (1984) The premenstrual syndrome: effects of medical "ovariectomy". N Engl J Med 311: 1345–1349

    Article  PubMed  CAS  Google Scholar 

  • O'Brien PM, Craven D, Selby C, Symonds EM (1979) Treatment of premenstrual syndrome by spironolactone. Br J Obstet Gynaecol 86: 142–147

    PubMed  Google Scholar 

  • O'Brien PMS, Abukhalil IEH, Henshaw C (1995) Premenstrual syndrome. Curr Obstet Gynaecol 5: 30–35

    Google Scholar 

  • O'Brien PMS, Abukhalil IEH (1999) Randomized controlled trial of the management of premenstrual syndrome and premenstrual mastalgia using luteal phase-only danazol. Am J Obstet Gynecol 180: 18–23

    PubMed  Google Scholar 

  • Taskin O, Gokdeniz R, Yalcinoglu A, Buhur A, Burak F, Atmaca R, Ozekici U (1998) Placebo-controlled cross-over study of effects of tibolone on premenstrual symptoms and peripheral beta-endorphin concentrations in premenstrual syndrome. Hum Reprod 13: 2402–2405

    PubMed  CAS  Google Scholar 

  • Rapkin AJ, Morgan M, Goldman L, Brann DW, Simone D, Mahesh VB (1997) Progesterone metabolite allopregnanolone in women with premenstrual syndrome. Obstet Gynecol 90: 709–714

    Article  PubMed  CAS  Google Scholar 

  • Roca CA, Schmidt PJ, Block M, Rubinow DR (1996) Implications of endocrine studies of premenstrual syndrome. Psychiatr Annuals 26: 576–580

    Google Scholar 

  • Roy-Byrne P, Rubinow DR, Gold PW, Post RM (1984) Possible antidepressant effect of oral contraceptives: case report. J Clin Psychiatry 45: 350–352

    PubMed  CAS  Google Scholar 

  • Rubinow DR, Hoban MC, Grover GN, Galloway DS, Roy-Byrne P, Anderson R, Merriam GR (1988) Changes in plasma hormones across the menstrual cycle in patients with menstrually related mood disorder and in control subjects. Am J Obstet Gynecol 158: 5–11

    PubMed  CAS  Google Scholar 

  • Rubinow DR, Schmidt PJ, Roca CA (1998) Estrogen-serotonin interactions: implications for affective regulation. Biol Psychiatry 44: 839–850.

    Article  PubMed  CAS  Google Scholar 

  • Sarno AP Jr, Miller EJ Jr, Lundblad EG (1987) Premenstrual syndrome: beneficial effects of periodic, low-dose danazol. Obstet Gynecol 70: 33–36

    PubMed  Google Scholar 

  • Schaller JL, Briggs B, Briggs M (2000) Progesterone organogel for premenstrual dysphoric disorder. J Am Acad Child Adolesc Psychiatry 39: 546–547

    PubMed  CAS  Google Scholar 

  • Schmidt PJ, Nieman LK, Danaceau MA, Adams LF, Rubinow DR (1998) Differential behavioral effects of gonadal steroids in women with and in those without premenstrual syndrome. N Engl J Med 338: 209–216

    Article  PubMed  CAS  Google Scholar 

  • Schmidt PJ, Nieman LK, Grover GN, Muller KL, Merriam GR, Rubinow DR (1991) Lack of effect of induced menses on symptoms in women with premenstrual syndrome. N Engl J Med 324: 1174–1179

    PubMed  CAS  Google Scholar 

  • Schmidt PJ, Purdy RH, Moore RH Jr, Paul SM, Rubinow DR (1994) Circulating levels of anxiolytic steroids in the luteal phase in women with premenstrual syndrome and in control subjects. J Clin Endocrin Metab 79: 1256–1260

    CAS  Google Scholar 

  • Scott RT Jr, Ross B, Anderson C, Archer DF (1991) Pharmacokinetics of percutaneous estradiol: a crossover study using a gel and a transdermal system in comparison with oral micronized estradiol. Obstet Gynecol 77: 758–764

    PubMed  Google Scholar 

  • Smith RN, Studd JW, Zamblera D, Nigel Holland EF (1995) A randomized comparison over 8 months of 100µg and 200µg twice weekly doses of transdermal oestradiol in the treatment of severe premenstrual syndrome. Br J Obstet Gynaecol 102: 475–484

    PubMed  CAS  Google Scholar 

  • Steiner M, Coote M, Wilkins A, Dunn E (1997) Biological correlates of irritability in women with premenstrual dysphoria. Eur Neuropsychopharmacol 7(Suppl 2): S172

    Google Scholar 

  • Steiner M, Dunn E, Born L (2002) Female-specific mood disorders. In: D'haenen H, den Boer JA, Willner P (eds) Biological psychiatry. Wiley, London, 849–859

    Google Scholar 

  • Steiner M, Haskett RF, Carroll BJ (1980) Premenstrual tension syndrome: The development of research diagnostic criteria and new rating scales. Acta Psychiatr Scand 62: 177–190

    PubMed  CAS  Google Scholar 

  • Sundstrom Poromaa I, Smith S, Gulinello M (2003) GABA receptors, progesterone and premenstrual dysphoric disorder. Arch Women Ment Health 6: 23–41

    PubMed  CAS  Google Scholar 

  • Sveindóttir H, Bäckström T (2000) Prevalence of menstrual cycle symptom cyclicity and premenstrual dysphoric disorder in a random sample of women using and not using oral contraceptives. Acta Obstet Gynecol Scand 79: 405–413

    PubMed  Google Scholar 

  • Walker A, Bancroft J (1990) Relationship between premenstrual symptoms and oral contraceptive use: a controlled study. Psychosom Med 52: 86–96

    PubMed  CAS  Google Scholar 

  • Wang M, Hammarbäck S, Lindhe B-Ã…, Bäckström T (1995) Treatment of premenstrual syndrome by spironolactone: A double-blind placebo-controlled study. Acta Obstet Gynecol Scand 74: 803–808

    PubMed  CAS  Google Scholar 

  • Wang M, Seippel L, Purdy RH, Backstrom T (1996) Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3, 20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one. J Clin Endocrin Metab 81: 1076–1082

    CAS  Google Scholar 

  • Watson NR, Studd JW, Savvas M, Garnett T, Baber RJ (1989) Treatment of severe premenstrual syndrome with oestradiol patches and cyclical oral norethisterone. Lancet 2: 730–732

    PubMed  CAS  Google Scholar 

  • West CP (1990) Inhibition of ovulation with oralprogestins-effectiveness in premenstrual syndrome. Eur J Obstet Gynecol Reproduct Biol 34: 119–128

    CAS  Google Scholar 

  • Willimann H, Walde P, Luisi PL, Gazzaniga A, Stroppolo F (1992) Lecithin organogel as matrix for transdermal transport of drugs. J Pharm Sci 81: 871–874

    PubMed  CAS  Google Scholar 

  • World Health Organization. International statistical classification of diseases and related problems, vol 10(ICD-10) (1992) World Health Organization Press, Geneva

    Google Scholar 

  • Wyatt K, Dimmock P, Jones P, Obhrai M, O'Brien S (2001) Efficacy of progesterone and progestogens in management of premenstrual syndrome: systematic review. Br Med J 323: 776–780

    CAS  Google Scholar 

  • Ylostalo P, Kauppila A, Puolakka J, Ronnberg L, Janne O (1982) Bromocriptine and norethisterone in the treatment of premenstrual syndrome. Obstet Gynecol 59: 292–298

    PubMed  CAS  Google Scholar 

  • Yonkers KA, Bradshaw KD, Halbreich U (2000) Oestrogens, progestins and mood. In: Steiner M, Yonkers KA, Eriksson E (eds) Mood disorders in women. Martin Dunitz, London, 207–232

    Google Scholar 

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Born, L., Steiner, M. (2005). Estrogens and Other Hormones in the Treatment of Premenstrual Syndromes. In: Bergemann, N., Riecher-Rössler, A. (eds) Estrogen Effects in Psychiatric Disorders. Springer, Vienna. https://doi.org/10.1007/3-211-27063-9_8

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