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Fluorinated-Gas MRI

  • Chapter
MRI of the Lung

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Fluorinated-gas MRI for ventilation imaging is an alternative approach to hyperpolarized-gas MRI using 3He or 129Xe, which may have the potential to be translated into clinical routine in the future. Although in general the contrast-to-noise ratio is less in fluorinated-gas MRI than that achieved with hyperpolarized gases, fluorinated-gas MRI has the advantage of comparatively simple technical requirements: An MRI system with multinuclear imaging capabilities and a dedicated fluorine-19 (19F) MRI coil is required. Manufactured fluorinated gases do not need a complex preparatory treatment on site before their use in patients and their signal-enhancing capabilities do not show a rapid decay. This makes their application less demanding for the local infrastructure and also reduces costs. These gases have not been approved as contrast agents for routine clinical ventilation MR imaging in most countries yet, which is the only major drawback to date.

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Authors and Affiliations

  1. Hannover Medical School, Institute of Diagnostic and Interventional Radiology, Carl-Neuberg Str. 1, Hannover, 30625, Germany

    Marcel Gutberlet & Jens Vogel-Claussen

  2. Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Hannover, Germany

    Marcel Gutberlet & Jens Vogel-Claussen

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  1. Marcel Gutberlet
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  2. Jens Vogel-Claussen
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Correspondence to Jens Vogel-Claussen .

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Editors and Affiliations

  1. Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany

    Hans-Ulrich Kauczor  & Mark Oliver Wielpütz  & 

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Gutberlet, M., Vogel-Claussen, J. (2017). Fluorinated-Gas MRI. In: Kauczor, HU., Wielpütz, M.O. (eds) MRI of the Lung. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2017_80

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  • DOI: https://doi.org/10.1007/174_2017_80

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-42616-7

  • Online ISBN: 978-3-319-42617-4

  • eBook Packages: MedicineMedicine (R0)

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