Key Points
Primary tumours of the chest wall and pleura are rare in comparison to tumours of the lung such as bronchial carcinomas. Chest wall tumours are a heterogeneous group that pose an interesting diagnostic challenge for radiologists. They make up less than 5% of thoracic malignancies and vary widely in pathology as they arise from all anatomic structures of the chest wall. Since chemotherapy is rarely effective and local control is the most important prognostic factor, wide local excision might be the solely curative treatment. Therefore, the margins need to be identified by imaging prior to surgery and adjuvant radiation, which might be applied in cases with positive margins. Malignant pleural mesothelioma is an aggressively growing tumour and a rising incidence is expected in the next decades. CT is still the general diagnostic tool for staging and therapy planning of malignant pleural mesothelioma. However, within the last years novel MRI techniques have been developed and introduced into clinical routine to improve tumour delineation and characterization in order to optimize individual therapy planning. Typical findings of those tumours using modern MRI techniques are discussed. Techniques are compared with CT and modern PET techniques, especially concerning characterization, precision of tumour delineation, therapy planning, and monitoring.
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References
Armato SG 3rd, Blyth KG, Keating JJ, Katz S, Tsim S, Coolen J, Gudmundsson E, Opitz I, Nowak AK (2016) Imaging in pleural mesothelioma: a review of the 13th international conference of the international mesothelioma interest group. Lung Cancer 101:48–58
Aslam M, Rajesh A, Entwisle J et al (2002) Pictorial review: MRI of the sternum and sternoclavicular joints. Br J Radiol 75:627–634
Baysal T, Bulut T, Gokimak M et al (2003) Diffusion-weighted MR imaging of pleural fluid: differentiation of transudative vs. exudative pleural effusions. Eur Radiol 14:890–896
Bibby AC, Tsim S, Kanellakis N, Ball H, Talbot DC, Blyth KG, Maskell NA, Psallidas I (2016) Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment. Eur Respir Rev 25(142):472–486
Butchart EG, Ashcroft T, Barnsley WC et al (1976) Pleuropneumonectomy in the management of diffuse malignant mesothelioma of the pleura. Experience with 29 patients. Thorax 31:15–24
Byrne MJ, Nowak AK (2004) Modified RECIST criteria for assessment of response in malignant pleural mesothelioma. Ann Oncol 15:257–260
David EA, Marshall MB (2011) Review of chest wall tumors: a diagnostic, therapeutic, and reconstructive challenge. Semin Plast Surg 25(1):16–24
Falaschi F, Boraschi P, Neri S et al (1995) High-resolution computed tomography (HRCT) in the detection of “early asbestosis”. Eur Radiol 5:291–296
Fiola C, Cantoni S, Turtulici I et al (1997) Transudative vs exudative pleural effusions: differentiation using Gd-DTPA-enhanced MRI. Eur Radiol 7:860–867
Ge W, Yu D-C, Chen G, Ding Y-T (2016) Clinical analysis of 47 cases of solitary fibrous tumor. Oncol Lett 12:2475–2480
Havelock T, Teoh R, Laws D, Gleeson F (2010) Pleural procedures and thoracic ultrasound: British Thoracic Society pleural disease guideline 2010. Thorax 65:i61–i76
Kishimoto T, Ohnishi K, Saito Y (2003) Clinical study of asbestos-related lung cancer. Ind Health 41:94–100
Koenigkam-Santos M, Sommer G, Puderbach M, Safi S, Schnabel PA, Kauczor HU, Heussel CP (2014) Primary intrathoracic malignant mesenchymal tumours: computed tomography features of a rare group of chest neoplasms. Insights Imaging 5:237–244
Laiho K, Soini I, Martio J (2001) Magnetic resonance imaging findings of manubriosternal joint involvement in SAPHO syndrome. Clin Rheumatol 20:232–233
Lynch DA, Gamsu G, Aberle DR (1989) Conventional and high resolution computed tomography in the diagnosis of asbestos-related diseases. Radiographics 9:523–551
McLoud TC, Flower CD (1991) Imaging of the pleura: sonography, CT, and MR imaging. Am J Roentgenol 156:1145–1152
Mitchell JD (2003) Solitary fibrous tumor of the pleura. Semin Thorac Cardiovasc Surg 15:305–309
Mossman BT, Gee JB (1989) Asbestos-related diseases. N Engl J Med. 320:1721–1730
Müller NL (1993) Imaging of the pleura. Radiology 186:297–309
Müller LP, Wolf HK, Heussel CP et al (1999) Bilateral elastofibroma dorsi. Chirurg 70:1357–1360
Pass H, Giroux D, Kennedy C, Ruffini E, Cangir AK, Rice D, Asamura H, Waller D, Edwards J, Weder W, Hoffmann H, van Meerbeeck JP, Nowak A, Rusch VW IASLC Staging and Prognostic Factors Committee, Advisory Boards and Participating Institutions. The IASLC mesothelioma staging project: improving staging of a rare disease through international participation. J Thorac Oncol 2016;11(12):2082–2088
Peacock C, Copley SJ, Hansell DM (2000) Asbestos-related benign pleural disease. Clin Radiol 55:422–432
Plathow C, Klopp M, Zuna I, Schmähl M, Kauczor HU (2008) Therapy response in malignant pleural mesothelioma – role of MRI using RECIST, Modified RECIST and volumetric approaches in comparison with CT. Eur Radiol 18:1635–1643
Rusch V (1996) A proposed new International TNM Staging System for malignant pleural mesothelioma from the International Mesothelioma Interest Group. Lung Cancer 14:1–12
Schwartz DA (1991) New developments in asbestos-induced pleural disease. Chest 99:191–198
Soeberg MJ, Leigh J, van Zandwijk N (2016) Malignant mesothelioma in Australia 2015: current incidence and asbestos exposure trends. J Toxicol Environ Health B Crit Rev 19(5–6):173–189
Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, Verweij J, Van Glabbeke M, van Oosterom AT, Christian MC, Gwyther SG (2000) New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 92:205–216
Tsao AS, Garland L, Redman M, Kernstine K, Gandara D, Marom EM (2011) A Practical Guide of the Southwest Oncology Group to Measure Malignant Pleural Mesothelioma Tumors by RECIST and Modified RECIST Criteria. J Thorac Oncol 6:598–601
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Heussel, C.P., Wielpütz, M.O., Kauczor, HU. (2017). Diseases of the Pleura and the Chest Wall. In: Kauczor, HU., Wielpütz, M.O. (eds) MRI of the Lung. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2017_50
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DOI: https://doi.org/10.1007/174_2017_50
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