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Stereotactic Body Radiotherapy with Functional Treatment Planning in Hepatocellular Carcinoma

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Alternate Fractionation in Radiotherapy

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

Hepatocellular carcinoma (HCC) is the fastest growing cause of cancer-related death in the United States, and considered an aggressive tumor with mean survival estimated between 6 and 20 months (El-Serag, NEJM 365:1118–1127, 2011). The choice of curative liver resection is limited by the presence of hepatic cirrhosis in 90% of patients, and the most appropriate therapy for HCC has historically been hepatic transplantation with 5-year survival rate of up to 85%. However, only 10% of patients are eligible for surgery (Fortune et al., J Clin Gastroenterol 47:S37–S42, 2013). We discuss functional treatment planning for patients with hepatic cirrhosis and HCC and present an argument in favor of liver SBRT as a viable option.

The original version of this chapter was revised. The affiliations of the authors have been updated.

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Authors and Affiliations

  1. Department of Radiation Oncology, Allegheny Health Network Cancer Institute, Pittsburgh, PA, USA

    Alexander Kirichenko & Shaakir Hasan

  2. MD Anderson Cancer Center, Houston, TX, USA

    Eugene J. Koay

  3. Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Christopher Crane

Authors
  1. Alexander Kirichenko
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  2. Eugene J. Koay
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  3. Shaakir Hasan
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  4. Christopher Crane
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Corresponding author

Correspondence to Alexander Kirichenko .

Editor information

Editors and Affiliations

  1. Allegheny General Hospital Allegheny Health Network Cancer Institute, Drexel University College of Medicine, Pittsburgh, PA, USA

    Mark Trombetta

  2. Radiation Oncology Department, Erasmus University Medical Center, Rotterdam, The Netherlands

    Jean-Philippe Pignol

  3. Allegheny Health Network, Temple University School of Medicine, Pittsburgh Campus, Pittsburgh, PA, USA

    Paolo Montemaggi

  4. Hylda Cohn/American Cancer Society, Drexel University College of Medicine, Philadelphia, PA, USA

    Luther W. Brady

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Kirichenko, A., Koay, E.J., Hasan, S., Crane, C. (2017). Stereotactic Body Radiotherapy with Functional Treatment Planning in Hepatocellular Carcinoma. In: Trombetta, M., Pignol, JP., Montemaggi, P., Brady, L.W. (eds) Alternate Fractionation in Radiotherapy. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2017_42

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  • DOI: https://doi.org/10.1007/174_2017_42

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-51197-9

  • Online ISBN: 978-3-319-51198-6

  • eBook Packages: MedicineMedicine (R0)

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