Abstract
Radiation therapy plays an integral role in the management of benign primary brain tumors as either primary or adjuvant treatment. These tumors are generally associated with good prognosis, which makes consideration of the risk of late treatment toxicity especially important. Though they are nonmalignant, benign primary brain tumors can certainly cause significant morbidity or even mortality owing to their intracranial and skull base locations, with possible mass effects on the cranial nerves or the brain itself. Given the competing considerations of toxicity and therapeutic need, controversy frequently surrounds the decision between the use of surgery and radiation therapy for primary treatment. When surgery is limited or resection is subtotal, there may also be controversy regarding the timing of. In radiation therapy addition, as technological advancements in planning and delivery of conformal radiation therapy allow for decreased risk of acute and long-term side effects, additional controversies over fractionation (e.g., standard fractionation versus radiosurgery) and the technique for delivery of radiation therapy (e.g., protons versus IMRT) are ongoing. In this chapter we highlight the controversies in management of meningioma, vestibular schwannoma, craniopharyngioma, pituitary adenoma, and glomus tumor and review the pertinent literature.
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Day, S.E., Halasz, L.M. (2017). Benign Primary Brain Tumors. In: Lo, S., Teh, B., Jiang, GL., Mayr, N. (eds) Controversies in Radiation Oncology. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2017_12
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