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Brain Tumours

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Re-Irradiation: New Frontiers

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Historically, radiation oncologists have approached re-irradiating brain tumours with caution due to the potential risks of central nervous system late toxicity, especially radionecrosis, which may occur months or years following treatment. There is, however, a paucity of prospective data addressing this approach. Re-irradiation of brain tumours is attracting more interest as our understanding of the tolerance of the brain to radiation evolves. Furthermore, developments in radiation treatment approaches, technology and imaging enable highly accurate targeting of biologically relevant tumour volumes. Thanks to recent advancements in molecular-targeted therapy, further exploration of the role of re-irradiation – primary or in combination with novel agents – is needed.

The original version of this chapter was revised. An erratum to this chapter can be found at 10.1007/978-3-319-41825-4_78.

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Acknowledgement

Susan C. Short and Jennifer E. Gains authored the brain tumours chapter for the first edition of this textbook. The present chapter is based on their updated manuscript.

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Authors and Affiliations

  1. Department of Radiation Oncology, James Comprehensive Cancer Center, The Ohio State University Columbus, Ohio, USA

    Joshua D. Palmer

  2. Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

    Colin Champ

  3. UCL Cancer Institute, London, UK

    Susan C. Short

  4. Department of Radiation Oncology, University of California, San Francisco, CA, USA

    Shannon E. Fogh

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Correspondence to Susan C. Short .

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Editors and Affiliations

  1. Department of Oncology, University of Tromso and Nordland Hospital, Bodo, Norway

    Carsten Nieder

  2. University Medical Center Groningen, Groningen, The Netherlands

    Johannes Langendijk

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Palmer, J.D., Champ, C., Short, S.C., Fogh, S.E. (2016). Brain Tumours. In: Nieder, C., Langendijk, J. (eds) Re-Irradiation: New Frontiers. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2016_66

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  • DOI: https://doi.org/10.1007/174_2016_66

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