Skip to main content

Re-irradiation for Recurrent Skin Cancer

  • Chapter
  • First Online:
Re-Irradiation: New Frontiers

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

Radiotherapy has an important role in the management of patients with cutaneous malignancy. Non-melanoma skin cancer (NMSC) is the most frequent malignancy worldwide, and as such the absolute number of patients receiving radiotherapy each year is high. An often and well-documented scenario is the development of a second NMSC, if not within a previous radiotherapy field, certainly in close proximity to a previous radiotherapy field, and therefore there may be a requirement to consider overlapping any new radiotherapy field with previously irradiated tissue, if other options are not considered. Published evidence for cutaneous re-irradiation is sparse especially as other options such as surgery are often available. Despite this select patients may be considered for re-irradiation, be that local or occasionally regional, especially where other options are not feasible.

The original version of this chapter was revised. An erratum to this chapter can be found at 10.1007/978-3-319-41825-4_78.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Babington S, Veness MJ, Cakir B, Gebski V, Morgan G (2003) Squamous cell carcinoma of the lip: does adjuvant radiotherapy improve local control following incomplete or inadequate excision? ANZ J Surg 73:621–625

    Article  PubMed  Google Scholar 

  • Barton M (1995) Tables of equivalent dose in 2 Gy fractions: a simple application of the linear quadratic formula. Int J Radiat Oncol Biol Phys 31:371–378

    Article  CAS  PubMed  Google Scholar 

  • Brotherston D, Poon I (2015) SBRT treatment of multiple recurrent auricular squamous cell carcinoma following surgical and conventional radiation treatment failure. Cureus 7, e325

    PubMed  PubMed Central  Google Scholar 

  • Chao CKS, Gerber RM, Perez CA (1995) Reirradiation of recurrent skin cancer of the face. Cancer 75:2351–2355

    Article  CAS  PubMed  Google Scholar 

  • Cognetta AB, Howard BM, Heaton HP et al (2012) Superficial x-ray in the treatment of basal and squamous cell carcinomas: a viable option in select patients. J Am Acad Dermatol 67:1235–1241

    Article  PubMed  Google Scholar 

  • Duprez F, Madani I, Bonte K et al (2009) Intensity-modulated radiotherapy for recurrent and second primary head and neck cancer in previously irradiated territory. Radiol Oncol 93:563–569

    Article  Google Scholar 

  • Ferro M, Deodata F, Macchia G et al (2015) Short-course radiotherapy in elderly patients with early stage non-melanoma skin cancer: A phase 2 study. Cancer Invest 33:34–38

    Google Scholar 

  • Fogarty GB, Hong A, Scolyer RA et al (2014) Radiotherapy for lentigo maligna: a literature review and recommendations for treatment. Br J Dermatol 170:52–58

    Article  CAS  PubMed  Google Scholar 

  • Gauden R, Pracy M, Avery AM et al (2013) HDR brachytherapy for superficial non-melanoma skin cancers. JMIRO 57:212–217

    PubMed  Google Scholar 

  • Gunaratne D, Howle J, Veness MJ (2016) Sentinel lymph node biopsy in Merkel cell carcinoma: a 15 year institutional experience and statistical analysis of 721 reported cases. BJD 174:273–281

    Google Scholar 

  • Henderson MA, Burmeister BH, Ainslie J et al (2015) Adjuvant lymph-node field radiotherapy versus observation only in patients with melanoma at high risk of further lymph-node field relapse after lymphadenectomy (ANZMTG 01.02/TROG 02.01): 6-year follow-up of a phase 3, randomised controlled trial. Lancet Oncol 16:1049–1060

    Article  PubMed  Google Scholar 

  • Hernandez-Machin B, Borrego L, Gil-Garcia M, Hernandez BH (2007) Office-based radiation therapy for cutaneous carcinoma: evaluation of 710 treatments. Int J Dermatol 46:453–459

    Article  PubMed  Google Scholar 

  • Hruby G, Scolyer RA, Thompson JF (2013) The important role of radiation treatment in the management of Merkel cell carcinoma. Br J Dermatol 169:975–982

    Article  CAS  PubMed  Google Scholar 

  • Hong A, Fogarty G (2012) Role of radiation therapy in cutaneous melanoma. Cancer J 18:203–207

    Article  PubMed  Google Scholar 

  • Kramkimel N, Dendal R, Bolle S, Zefkili S, Fourquet A, Kirova YM (2014) Management of advanced non-melanoma skin cancers using helical tomotherapy. JEADV 28:641–650

    CAS  PubMed  Google Scholar 

  • Marcil I, Stern RS (2000) Risk of developing a subsequent nonmelanoma skin cancer in patients with a history of nonmelanoma skin cancer: a critical review of the literature and meta-analysis. Arch Dermatol 136:1524–1530

    Article  CAS  PubMed  Google Scholar 

  • Perera E, Gnaneswaran N, Staines C, Win AK, Sinclair R (2015) Incidence and prevalence of non-melanoma skin cancer in Australia: a systematic review. Austral J Dermatol 56:258–267

    Article  Google Scholar 

  • Porceddu S, Veness M, Guminski A (2015) Non-melanoma cutaneous head and neck cancer and Merkel cell carcinoma – Current concepts, advances and controversies. J Clin Oncol 33:3338–3345

    Google Scholar 

  • Simmonds RH, Hopewell JW, Robbins ME (1989) Residual radiation-induced injury in dermal tissue: implications for retreatment. Br J Radiol 62:915–920

    Article  CAS  PubMed  Google Scholar 

  • Smith SP, Grande DJ (1991) Basal cell carcinoma recurring after radiotherapy: a unique, difficult treatment subclass of recurrent basal cell carcinoma. J Dermatol Surg Oncol 17:26–10

    Article  CAS  PubMed  Google Scholar 

  • Smith TL, Morris CG, Mendenhall NP (2014) Angiosarcoma after breast-conserving therapy: Long-term disease control and late effects with hyperfractionated accelerated re-irradiation (HART). Acta Oncol 53:235–241

    Google Scholar 

  • Van Hezewijk M, Creutzberg CL, Putter H et al (2010) Efficacy of a hypofractionated schedule in electron beam radiotherapy for epithelial skin cancer: analysis of 434 cases. Radiol Oncol 95:245–249

    Article  Google Scholar 

  • Veness MJ (2008) The important role of radiotherapy in patients with non-melanoma skin cancer and other cutaneous entities. JMIRO 52:278–286

    CAS  PubMed  Google Scholar 

  • Veness M, Howle J (2015) Radiotherapy alone in patients with Merkel cell carcinoma: the Westmead hospital experience of 41 patients. Australas J Dermatol 56:19–24

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michael J. Veness .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Veness, M.J., Sundaresan, P. (2016). Re-irradiation for Recurrent Skin Cancer. In: Nieder, C., Langendijk, J. (eds) Re-Irradiation: New Frontiers. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2016_37

Download citation

  • DOI: https://doi.org/10.1007/174_2016_37

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-41823-0

  • Online ISBN: 978-3-319-41825-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics