Abstract
Three-dimensional conformal radiation therapy (3DCRT) has been the standard technique for hepatocellular carcinoma (HCC). Intensity-modulated radiation therapy (IMRT) may be useful to improve target coverage and for normal organ sparing, especially in the setting of unusually shaped target volumes. More recently, stereotactic body radiation therapy (SBRT) has been increasingly used. Individualized prescription doses are commonly used due to variable liver volume irradiation and proximity to luminal gastrointestinal tissues.
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Further Reading
Bi AH et al (2010) Impact factors for microinvasion in intrahepatic cholangiocarcinoma: a possible system for defining clinical target volume. Int J Radiat Oncol Biol Phys 78:1427–1436
Cheng JC et al (2000) Local radiotherapy with or without transcatheter arterial chemoembolization for patients with unresectable hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 47:435–442
Todoroki T et al (2000) Benefits of adjuvant radiotherapy after radical resection of locally advanced main hepatic duct carcinoma. Int J Radiat Oncol Biol Phys 46:581–587
Tse RV et al (2008) Phase I study of individualized stereotactic radiotherapy for hepatocellular carcinoma and intrahepatic cholangiocarcinoma. J Clin Oncol 26:657–664
Tsuji T et al (2001) Lymphatic spreading pattern of intrahepatic cholangiocarcinoma. Surgery 129:401–407
Wang NH et al (2010) Impact factors for microinvasion in patients with hepatocellular carcinoma: possible application to the definition of clinical tumor volume. Int J Radiat Oncol Biol Phys 76:467–476
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© 2014 Springer International Publishing Switzerland
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Cheng, J.CH., Wang, CC., Miguel, I.S., Dawson, L.A. (2014). Hepatocellular Carcinoma and Cholangiocarcinoma. In: Lee, N.Y., Riaz, N., Lu, J.J. (eds) Target Volume Delineation for Conformal and Intensity-Modulated Radiation Therapy. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2014_978
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DOI: https://doi.org/10.1007/174_2014_978
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