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Sarcoma

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Decision Tools for Radiation Oncology

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Soft tissue sarcomas are malignant tumors that arise in the mesoderm. There are over 50 subtypes of these tumors that vary greatly in biological behavior. While small, low-grade lesions may be adequately treated by resection alone; larger, higher-grade lesions require adjuvant therapy to maximize local control. We will examine the prognostic factors that predict for disease recurrence and the role of radiation therapy in this setting. We will also examine the toxicities associated with radiation, and how this information is utilized to help or guide decision making for the treatment of soft tissue sarcomas.

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Notes

  1. 1.

    This corresponds to Table 33.5 and 33.6 (page 950 and 951) “Decision making in radiation oncology” (Lu and Brady)

Abbreviations

STS:

Soft tissue sarcoma

SO:

Second opinion

AJCC:

American Joint Committee on Cancer

MSKCC:

Memorial Sloan-Kettering Cancer Center

DFS:

Disease-free survival

OS:

Overall survival

MDACC:

University of Texas M. D. Anderson Cancer Center

MGH:

Massachusetts General Hospital

PMH:

The Princess Margaret Hospital

RLNM:

Regional lymph node metastases

MPNST:

Malignant peripheral-nerve tumor

CI:

Concordance index

LS:

Liposarcoma

GPS:

General postoperative sarcoma nomogram from MSKCC

DSS:

Disease-specific survival

pathCR:

Greater than or equal to 95 % necrosis

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Authors and Affiliations

  1. Department of Radiation Oncology, Abramson Cancer Center, Hospital of the University of Pennsylvania, PCAM, TRC 2 West, 3400 Civic Center Blvd, Philadelphia, PA, USA

    William P. Levin

  2. Connective Tissue Oncology Center, Francis H. Burr Proton Therapy Center, Radiation Oncology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA

    Thomas F. DeLaney

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Correspondence to William P. Levin .

Editor information

Editors and Affiliations

  1. Department of Oncology, Nordland Hospital Trust Bodø University of Tromsø, Bodø, Norway

    Carsten Nieder

  2. Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado, USA

    Laurie E. Gaspar

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Levin, W.P., DeLaney, T.F. (2013). Sarcoma. In: Nieder, C., Gaspar, L. (eds) Decision Tools for Radiation Oncology. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2013_857

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  • DOI: https://doi.org/10.1007/174_2013_857

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-37101-1

  • Online ISBN: 978-3-642-37102-8

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