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Pitfalls and Artifacts

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PET-CT and PET-MRI in Oncology

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

FDG PET is extremely useful in staging and restaging cancer, differentiating malignant from benign processes, and locating otherwise occult sites of malignancy. However, areas of real or apparent FDG activity do not always represent malignancy. In this chapter we will review the more common categories of pitfalls and artifacts and how they can be recognized and avoided. Pitfalls arise when real benign biologic processes result in imaging findings that mimic malignancy. Common pitfalls are seen with abnormal nonmalignant biologic processes, as well as normal physiologic and anatomic variation. Artifacts are imaging findings that arise in the process of patient preparation and imaging. Artifacts can mimic real biologic processes, or can negatively affect the interpretation of real biologic processes. Common artifacts result from errors related to attenuation correction, motion, truncation, glucose and insulin, FDG injection and uptake. When combining PET and CT imaging, some pitfalls and artifacts are avoided, while others may be newly created or multiplied.

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Authors and Affiliations

  1. Department of Radiology and Immunology, Mayo Clinic, Rochester, MN, USA

    Geoffrey Bates Johnson & Christopher Harker Hunt

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  1. Geoffrey Bates Johnson
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  2. Christopher Harker Hunt
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Editors and Affiliations

  1. Rochester, 55901, Minnesota, USA

    Patrick Peller

  2. , Division of Neuroradiology, Boston University School of Medicine, Boston, 02493, Massachusetts, USA

    Rathan Subramaniam

  3. Dept. Radiology, Boston University Medical Center, E. Newton St. 88, Boston, 02118, Massachusetts, USA

    Ali Guermazi

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Johnson, G.B., Hunt, C.H. (2012). Pitfalls and Artifacts. In: Peller, P., Subramaniam, R., Guermazi, A. (eds) PET-CT and PET-MRI in Oncology. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2012_708

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  • DOI: https://doi.org/10.1007/174_2012_708

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