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PET/CT Interpretation

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PET-CT and PET-MRI in Oncology

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

PET/SPECT interpretation is a challenging task, which is aided by a systematic approach to image review. The PET/SPECT report is the final product of interpretation and needs to be crafted carefully. The impression should answer the referring physician's clinical question and delineate all diagnoses requiring his action. A thorough knowledge of the normal distribution of FDG is very important for PET/CT interpretation.

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References

  • ACR practice guideline for performing FDG-PET/CT in oncology. http://www.acr.org/SecondaryMainMenuCategories/quality_safety/guidelines/nuc_med/fdg_pet_ct.aspx. Accessed 10 Jan 2012

  • Agress H Jr, Wong TZ, Shreve P (2008) Interpretation and reporting of positron emission tomography-computed tomographic scans. Semin Ultrasound CT MR 29(4):283–90

    Article  PubMed  Google Scholar 

  • Ak I, Stokkel MP, Pauwels EK (2000) Positron emission tomography with 2-[18F]fluoro-2-deoxy-d-glucose in oncology. Part II. The clinical value in detecting and staging primary tumours. J Cancer Res Clin Oncol 126(10):560–74

    Article  PubMed  CAS  Google Scholar 

  • Brink I, Reinhardt MJ, Hoegerle S, Altehoefer C, Moser E, Nitzsche EU (2001) Increased metabolic activity in the thymus gland studied with 18F-FDG PET: age dependency and frequency after chemotherapy. J Nucl Med 42(4):591–5

    PubMed  CAS  Google Scholar 

  • CMS released Transmittals R108 NCD; R1833 CP rescinding transmittals R106 NCD and R1817 CP. http://www.cms.gov/transmittals/downloads/R108NCD.pdf. Accessed 10 Jan 2012

  • Coleman RE, Hillner BE, Shields AF et al (2010) PET and PET/CT reports: observations from the National Oncologic PET Registry. J Nucl Med 51:158–163

    Article  PubMed  Google Scholar 

  • Culverwell AD, Scarsbrook AF, Chowdhury FU (2011) False-positive uptake on 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography/computed tomography (PET/CT) in oncological imaging. Clin Radiol 66(4):366–82

    Article  PubMed  CAS  Google Scholar 

  • Dilsizian V, Bacharach SL, Khin MM, Smith MF (2001) Fluorine-18-deoxyglucose SPECT and coincidence imaging for myocardial viability: clinical and technologic issues. J Nucl Cardiol 8(1):75–88

    Article  PubMed  CAS  Google Scholar 

  • El-Haddad G, Alavi A, Mavi A, Bural G, Zhuang H (2004) Normal variants in [18F]-fluorodeoxyglucose PET imaging. Radiol Clin North Am 42(6):1063–81

    Article  PubMed  Google Scholar 

  • Ferdinand B, Gupta P, Kramer EL (2004) Spectrum of thymic uptake at 18F-FDG PET. Radiographics 24(6):1611–6

    Article  PubMed  Google Scholar 

  • Goerres GW, Von Schulthess GK, Hany TF (2002) Positron emission tomography and PET/CT of the head and neck: FDG uptake in normal anatomy, in benign lesions, and in changes resulting from treatment. AJR Am J Roentgenol 179(5):1337–43

    PubMed  Google Scholar 

  • Gontier E, Fourme E, Wartski M, Blondet C, Bonardel G, Le Stanc E, Mantzarides M, Foehrenbach H, Pecking AP, Alberini JL (2008) High and typical 18F-FDG bowel uptake in patients treated with metformin. Eur J Nucl Med Mol Imaging 35(1):95–9

    Article  PubMed  CAS  Google Scholar 

  • Hicks RJ, Binns D, Stabin MG (2001) Pattern of uptake and excretion of (18)F-FDG in the lactating breast. J Nucl Med 42(8):1238–42

    PubMed  CAS  Google Scholar 

  • Israel O, Yefremov N, Bar-Shalom R, Kagana O, Frenkel A, Keidar Z, Fischer D (2005) PET/CT detection of unexpected gastrointestinal foci of 18F-FDG uptake: incidence, localization patterns, and clinical significance. J Nucl Med 46(5):758–62

    PubMed  Google Scholar 

  • Kamel EM, Jichlinski P, Prior JO, Meuwly JY, Delaloye JF, Vaucher L, Malterre J, Castaldo S, Leisinger HJ, Delaloye AB (2006) Forced diuresis improves the diagnostic accuracy of 18F-FDG PET in abdominopelvic malignancies. J Nucl Med 47(11):1803–7

    PubMed  CAS  Google Scholar 

  • Karantanis D, Bogsrud TV, Wiseman GA, Mullan BP, Subramaniam RM, Nathan MA, Peller PJ, Bahn RS, Lowe VJ (2007) Clinical significance of diffusely increased 18F-FDG uptake in the thyroid gland. J Nucl Med 48(6):896–901

    Article  PubMed  CAS  Google Scholar 

  • Kitajima K, Nakamoto Y, Senda M, Onishi Y, Okizuka H, Sugimura K (2007) Normal uptake of 18F-FDG in the testis: an assessment by PET/CT. Ann Nucl Med 21(7):405–10

    Article  PubMed  Google Scholar 

  • Kostakoglu L, Agress H Jr, Goldsmith SJ (2003) Clinical role of FDG PET in evaluation of cancer patients. Radiographics 23(2):315–40

    Article  PubMed  Google Scholar 

  • Lerman H, Metser U, Grisaru D, Fishman A, Lievshitz G, Even-Sapir E (2004) Normal and abnormal 18F-FDG endometrial and ovarian uptake in pre- and postmenopausal patients: assessment by PET/CT. J Nucl Med 45(2):266–71

    PubMed  Google Scholar 

  • Nakamoto Y, Tatsumi M, Hammoud D, Cohade C, Osman MM, Wahl RL (2005) Normal FDG distribution patterns in the head and neck: PET/CT evaluation. Radiology 234(3):879–85

    Article  PubMed  Google Scholar 

  • Ozülker T, Ozülker F, Mert M, Ozpaçaci T (2010) Clearance of the high intestinal (18)F-FDG uptake associated with metformin after stopping the drug. Eur J Nucl Med Mol Imaging 37(5):1011–7

    Article  PubMed  Google Scholar 

  • Reiner BI, Knight N, Siegel EL (2007) Radiology reporting, past, present, and future: the radiologist’s perspective. J Am Coll Radiol 4:313–319

    Article  PubMed  Google Scholar 

  • Skehan SJ, Brown AL, Thompson M, Young JE, Coates G, Nahmias C (2000) Imaging features of primary and recurrent esophageal cancer at FDG PET. Radiographics 20(3):713–23

    PubMed  CAS  Google Scholar 

  • SNM PET pros, elements of PET/CT reporting. http://www.snm.org/docs/PET_PROS/ElementsofPETCTReporting.pdf. Accessed 10 Jan 2012

  • Tatlidil R, Jadvar H, Bading JR, Conti PS (2002) Incidental colonic fluorodeoxyglucose uptake: correlation with colonoscopic and histopathologic findings. Radiology 224(3):783–7

    Article  PubMed  Google Scholar 

  • Townsend DW (2008) Combined positron emission tomography-computed tomography: the historical perspective. Semin Ultrasound CT MR 29(4):232–5

    Article  PubMed  Google Scholar 

  • Vranjesevic D, Schiepers C, Silverman DH, Quon A, Villalpando J, Dahlbom M, Phelps ME, Czernin J (2003) Relationship between 18F-FDG uptake and breast density in women with normal breast tissue. J Nucl Med 44(8):1238–42

    PubMed  Google Scholar 

  • Zhuang H, Kumar R, Mandel S, Alavi A (2004) Investigation of thyroid, head, and neck cancers with PET. Radiol Clin North Am 42(6):1101–11

    Article  PubMed  Google Scholar 

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Correspondence to Patrick J. Peller .

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© 2012 Springer-Verlag Berlin Heidelberg

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Peller, P.J. (2012). PET/CT Interpretation. In: Peller, P., Subramaniam, R., Guermazi, A. (eds) PET-CT and PET-MRI in Oncology. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2012_602

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  • DOI: https://doi.org/10.1007/174_2012_602

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-01138-2

  • Online ISBN: 978-3-642-01139-9

  • eBook Packages: MedicineMedicine (R0)

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