Abstract
Advances in radiotherapy planning and delivery in the past decade, including the increased use of three-dimensional conformal radiotherapy and intensity-modulated radiotherapy (IMRT), have made accurate tumor volume delineation critical for radiotherapy planning, particularly since IMRT results in sharp dose gradients between normal tissue and the tumor. As a result, with the simultaneous rapid growth of PET/CT utilization, integration of PET/CT into radiotherapy planning has been important for accurate and consistent tumor volume delineation, improved identification of nodal and distant metastatic disease and assessing response to radiotherapy. Determining the optimal method of using PET/CT for tumor volume delineation with different methods of volumetric segmentation is currently being studied. Experimental studies with novel PET tracers and applications of PET to adaptive radiotherapy planning based on PET/CT response are also being carried out. PET/CT is an important imaging modality for radiotherapy planning in many solid tumors.
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Truong, M.T., Subramaniam, R.M. (2012). Radiotherapy Planning. In: Peller, P., Subramaniam, R., Guermazi, A. (eds) PET-CT and PET-MRI in Oncology. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2012_580
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