Abstract
In this chapter the basic principles of positron emission tomography (PET) imaging will be introduced. The physics of coincidence detection and the instrumentation used to acquire PET data will be presented. Finally, the factors that degrade PET image quality and the correction techniques employed to compensate for these factors will be reviewed.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Badawi RD, Dahlbom M (2005) NEC: some coincidences are more equivalent than others. J Nucl Med 46:1767–1768
Beneditti SD, Cowan CE, Konneker WR et al (1950) On the angular distribution of two photon annihilation radiation. Phys Rev 77:205–212
Casey ME, Nutt R (1986) A multi-slice two-dimensional BGO detector system for PET. IEEE Trans Nucl Sci 33:760–763
Cherry SR (2006) The 2006 Henry N. Wagner lecture: of mice and men (and positrons)—advances in PET imaging technology. J Nucl Med 47:1735–1745
Cherry SR, Dahlbom M, Hoffman EJ (1991) 3D PET using a conventional multislice tomograph without septa. J Comput Assis Tomogr 15:655–668
Humm JL, Rozenfeld A, Del Guerra A (2003) From PET detectors to PET scanners. Eur J Nucl Med Mol Imaging 30:1574–1594
Karp JS, Surti S, Daube-Witherspoon ME, Muehllehner G (2008) Benefit of time-of-flight in PET: experimental and clinical results. J Nucl Med 49:462–470
Kinahan PE, Hasegawa BH, Beyer T (2003) X-ray-based attenuation correction for positron emission tomography/computed tomography scanners. Semin Nucl Med 33:166–179
Levin CS, Hoffman EJ (1999) Calculation of positron range and its effect on the fundamental limit of positron emission tomography system spatial resolution. Phys Med Biol 44:781–799
Lewellen TK (1998) Time-of-flight PET. Semin Nucl Med 28:268–275
Pichler BJ, Judenhofer MS, Catana C, Walton JH et al (2006) Performance test of an LSO-APD detector in a 7-T MRI scanner for simultaneous PET/MRI. J Nucl Med 47:639–647
Strother SC, Casey ME, Hoffman EJ (1990) Measuring PET sensitivity: relating count rates to image-signal-to-noise ratio using noise equivalent counts. IEEE Trans Nucl Sci 37:783–788
Ter Pogossian MM, Mullani NA, Ficke DC (1981) Photon time-of-flight assisted positron emission tomography. J Comput Assist Tomogr 5:227–239
Tomitani T (1981) Image-reconstruction and noise evaluation in photon time-of-flight assisted positron emission tomography. IEEE Trans Nucl Sci 28:4582–4589
Townsend DW, Geissbuhler A, Defrise M et al (1991) Fully 3-dimensional reconstruction for a PET camera with retractable septa. IEEE Trans Med Imag 10:505–512
Wong W-H, Uribe J, Hicks K, Hu G (1995) An analog decoding BGO block detector using circular photomultipliers. IEEE Trans Nucl Sci 42:1095–1101
Further Reading
Bendriem B, Townsend DW (1998) The theory and practice of 3D PET. Kluwer, Dordrecht
Cherry SR, Sorenson JA, Phelps ME (2003) Physics in nuclear medicine, 3rd edn. W.B. Saunders, New York
Knoll GF (2010) Radiation detection and measurement, 4th edn. Wiley, New York
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Kemp, B. (2012). PET Physics and Instrumentation. In: Peller, P., Subramaniam, R., Guermazi, A. (eds) PET-CT and PET-MRI in Oncology. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_526
Download citation
DOI: https://doi.org/10.1007/174_2011_526
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-01138-2
Online ISBN: 978-3-642-01139-9
eBook Packages: MedicineMedicine (R0)