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Technical Basis of Radiation Therapy pp 801–827Cite as

Bladder Cancer

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Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

The management of invasive bladder cancer requires a multidisciplinary approach to optimize the treatment of the disease while maintaining the best quality of life. In early-stage disease, combined surgery and radiation offers good results with sparing of the functional bladder in selected patients. For patients with locally advanced disease, maximal transurethral resection followed by radiotherapy and possibly chemotherapy can offer a valuable alternative to radical surgical approaches. A wide variety of planning, dosing, and actual therapy techniques is nowadays available. A challenge in radiotherapy for bladder cancer is caused by organ motion, which limits the precision of radiotherapy for bladder cancer. New treatment techniques and tools for image guidance and adaptive radiotherapy increase precision of dose delivery together with a substantial reduction of treatment volumes. Further investigations toward defining optimal fractionation schemes, techniques, and systemic agents remain to be continued. The development of new diagnostic tools utilizing molecular markers is being explored to further individualize the treatments to the patient with his/her specific tumor characteristics.

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Authors and Affiliations

  1. Department of Radiation Oncology, State University of New York, Health Science Center at Brooklyn, 450 Clarkson Aven, Box 1211, Brooklyn, NY, 11203-2098, USA

    Peter Han, Marvin Rotman & Alan R. Schulsinger

  2. Department of Radiation Oncology, Long Island College Hospital, Brooklyn, NY, USA

    Alan R. Schulsinger

  3. Department of Radiation Oncology, Academic Medical Center/University of Amsterdam, P.O. Box 22660, Z0-214, 1100 DD, Amsterdam, The Netherlands

    Bradley R. Pieters, Caro C. E. Koning & Maarten C. C. M. Hulshof

  4. Department of Radiation Oncology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands

    Floris J. Pos

  5. Department of Radiation Oncology, Institute Verbeeten, Tilburg, The Netherlands

    Philip Poortmans

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  1. Peter Han
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Correspondence to Peter Han .

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Editors and Affiliations

  1. Institutet Stockholm Sweden, MMC 436, Dept.of Oncol-Pathol Karolinska, Delaware St. SE 420, Minneapolis, 55455, Minnesota, USA

    Seymour H. Levitt

  2. UC Davis Cancer Center, Dept. Radiation Oncology, University of California, Davis, X Street 4501, Sacramento, 95817, California, USA

    James A. Purdy

  3. School of Medicine, Dept. Radiation Oncology, Washington University, Forest Park Ave. 4511, St. Louis, 63108-2138, Michigan, USA

    Carlos A. Perez

  4. Instituut Verbeeten, Tilburg, 5042 SB, Netherlands

    Philip Poortmans

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Han, P. et al. (2011). Bladder Cancer. In: Levitt, S., Purdy, J., Perez, C., Poortmans, P. (eds) Technical Basis of Radiation Therapy. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_249

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