Abstract
The contribution of imaging in disorders of sex development is not confined to the diagnosis of the underlying condition. Imaging has an important role in assisting pre-operative planning where surgery is contemplated, in identifying the location of occult gonads and in assessment of suspected complications of these conditions, including malignant transformation. In each of these scenarios, close collaboration with paediatric endocrinologists and paediatric surgeons is essential if an appropriate management strategy is to be adopted, as imaging is of greatest value where the radiologist is aware of the context in which it is performed.
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Abbreviations
- DSD:
-
Disorders of sex development
- AMH:
-
Anti-Müllerian Hormone
- SRY:
-
Sex determining region of the Y chromosome
- AR:
-
Androgen receptor
- 21-OHD:
-
21-hydroxylase deficiency
- AMH:
-
Anti-Müllerian hormone
- AMHR:
-
Anti-Müllerian hormone receptor
- US:
-
Ultrasound
- CT:
-
Computed Tomography
- MRI:
-
Magnetic Resonance Imaging
- TUM:
-
Total Urogenital Mobilisation
- INSL3:
-
Insulin-like 3
- T:
-
Testosterone
- DHT:
-
Dihydrotestosterone
- SF-1:
-
Steroidogenic factor 1
- WT-1:
-
Wilm’s tumour-1
- SOX-9:
-
SRY box 9
- DAX-1:
-
Dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome gene 1
- StAR:
-
steroidogenic acute regulatory
- LH:
-
Luteinising hormone
- TFT:
-
Thyroid function tests
- FSH:
-
Follicle stimulating hormone
- DHEAS:
-
Dehydroepiandrosterone sulfate
- HCG:
-
Human chorionic gonadotropin
- MHz:
-
Megahertz
- LHRH:
-
Luteinising hormone releasing hormone
- 17-hydroxy-progesterone:
-
17-OH progesterone
- AR:
-
Androgen receptor
- MCUG:
-
Micturating Cystourethrogram
- PAIS:
-
Partial Androgen Insensitivity Syndrome
- AIS:
-
Androgen Insensitivity Syndrome
- CAIS:
-
Complete Androgen Insensitivity Syndrome
- CAH:
-
Congenital Adrenal Hyperplasia
- LGR8:
-
Leucine-rich repeat-containing G-protein-coupled receptor 8
- ACTH:
-
Adrenocorticotropic Hormone
- GH:
-
Growth hormone
- AVP:
-
Arginine vasopressin
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Davies, J.H., Malone, P.S., Fairhurst, J. (2010). Disorders of Sex Development. In: Mann, G., Blair, J., Garden, A. (eds) Imaging of Gynecological Disorders in Infants and Children. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2010_81
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DOI: https://doi.org/10.1007/174_2010_81
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