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Pulmonary Nodules and Lung Cancer

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Dual Energy CT in Clinical Practice

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Worldwide, lung cancer is the leading cause of cancer mortality in men and women. The therapeutic options for lung cancer have been substantially improved. Sophisticated surgical techniques have increased the number of patients considered as being technically resectable. On the other hand, multimodal treatment strategies using induction chemotherapy or radiotherapy have increased the number of patients finally undergoing surgical resection. But even in inoperable patients, new chemotherapeutic agents or targeted therapies have improved the survival of patients with lung cancer. As a consequence, the demands for diagnostic radiology in patients with lung cancer have changed. The differentiation of iodinated contrast media by DECT is a potential surrogate marker for regional blood volume and thus angiogenesis, which has already been used for non-invasive characterization of pulmonary nodules. Future studies have to evaluate further potential applications of DECT in lung cancer staging and response evaluation.

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Authors and Affiliations

  1. Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany

    Thomas Henzler & Christian Fink

  2. Interdisciplinary Thoracic Oncology, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany

    Gerald Schmid-Bindert

Authors
  1. Thomas Henzler
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  2. Gerald Schmid-Bindert
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  3. Christian Fink
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Corresponding author

Correspondence to Thomas Henzler .

Editor information

Editors and Affiliations

  1. Klinikum Großhadern, Institut für Klinische Radiologie, Universitätsklinikum München, Marchioninistr. 15, München, 81377, Germany

    Thorsten Johnson

  2. Institut für Klinische Radiologie, Universitätsklinikum Med. Fak. Mannheim, Klinikum Mannheim gGmbH, Theodor-Kutzer Ufer 1-3, Mannheim, 68167, Germany

    Christian Fink

  3. Institut für Klinische Radiologie, Universitätsklinikum Med. Fak. Mannheim, Klinikum Mannheim gGmbH, Theodor-Kutzer Ufer 1-3, Mannheim, 68167, Germany

    Stefan O. Schönberg

  4. Klinikum Großhadern, Institut für Klinische Radiologie, Universitätsklinikum München, Marchioninistr. 15, München, 81377, Germany

    Maximilian F. Reiser

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© 2011 Springer-Verlag Berlin Heidelberg

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Henzler, T., Schmid-Bindert, G., Fink, C. (2011). Pulmonary Nodules and Lung Cancer. In: Johnson, T., Fink, C., Schönberg, S., Reiser, M. (eds) Dual Energy CT in Clinical Practice. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2010_53

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  • DOI: https://doi.org/10.1007/174_2010_53

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-01739-1

  • Online ISBN: 978-3-642-01740-7

  • eBook Packages: MedicineMedicine (R0)

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