Skip to main content
Book cover

Fetal MRI pp 247–258Cite as

MRI of the Fetal Heart

  • Chapter
  • First Online:

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Visualization of the fetal heart with MRI is complicated because of the small size of the fetal heart and the high heart rate of app­roximately 140 beats per minute. While con­ventional T2-weighted sequences only allow assessment of its size and position, steady-state free-precession sequences are currently the best way to image the fetal heart. The anatomical detail that can be depicted depends on fetal size and on section plane. However, as cardiac triggering is not possible in the fetal setting, the images are taken at random points in the fetal cardiac cycle. This leads to blurring and prevents exact visualization of the thin moving parts, such as the cusps and valves. This may be partly overcome by using dynamic sequences. While a variety of fetal cardiac malformations, especially those associated with cardiomegaly, can also be detected with MRI, its additional value in evaluating fetal cardiac pathologies remains to be determined.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Allwork SP, Anderson RH (1979) Developmental anatomy of the membranous part of the ventricular septum in the human heart. Br Heart J 41:275–280

    Article  PubMed  CAS  Google Scholar 

  • Amaral HB, Zielinsky P, da Silveira AF, Costabeber I, Nicoloso LH, de Souza Filho OC, Salum M, Manica JL, Zanettini JS, Costabeber AM (2007) Morphological basis for the study of the interatrial septum in the human fetus. Arq Bras Cardiol 88:559–564

    Article  PubMed  Google Scholar 

  • Amin RS, Nikolaidis P, Kawashima A, Kramer LA, Ernst RD (1999) Normal anatomy of the fetus at MR imaging. Radiographics 19(spec no):S201–S214

    Google Scholar 

  • Arteaga-Martinez M, Halley-Castillo E, Garcia-Pelaez I, Villasis-Keever MA, Aguirre OM, Vizcaino-Alarcon A (2009) Morphometric study of the ventricular segment of the human fetal heart between 13 and 20 weeks’ gestation. Fetal Pediatr Pathol 28:78–94

    Article  PubMed  Google Scholar 

  • Brandt W (1954) Fetal circulation and the development of the prime movers of right atrioventricular ring in the human heart. Acta Anat (Basel) 22:216–227

    Article  CAS  Google Scholar 

  • Budorick NE, Millman SL (2000) New modalities for imaging the fetal heart. Semin Perinatol 24:352–359

    Article  PubMed  CAS  Google Scholar 

  • Castillo EH, Arteaga-Martinez M, Garcia-Pelaez I, Villasis-Keever MA, Aguirre OM, Moran V, Vizcaino Alarcon A (2005) Morphometric study of the human fetal heart. I. Arterial segment. Clin Anat 18:260–268

    Article  PubMed  Google Scholar 

  • Conte G, Grieco M (1984) Closure of the interventricular foramen and morphogenesis of the membranous septum and ventricular septal defects in the human heart. Anat Anz 155:39–55

    PubMed  CAS  Google Scholar 

  • Douglas YL, Jongbloed MR, Gittenberger-de Groot AC, Evers D, Dion RA, Voigt P, Bartelings MM, Schalij MJ, Ebels T, DeRuiter MC (2006) Histology of vascular myocardial wall of left atrial body after pulmonary venous incorporation. Am J Cardiol 97:662–670

    Article  PubMed  Google Scholar 

  • Ertl-Wagner B, Lienemann A, Strauss A, Reiser MF (2002) Fetal magnetic resonance imaging: indications, technique, anatomical considerations and a review of fetal abnormalities. Eur Radiol 12:1931–1940

    PubMed  Google Scholar 

  • Figueira RR, Prates JC, Hayashi H (1991) Development of the pars membranacea septi interventricularis of the human heart. II. Thickness change. Arch Ital Anat Embriol 96:303–307

    PubMed  CAS  Google Scholar 

  • Fogel MA, Wilson RD, Flake A, Johnson M, Cohen D, McNeal G, Tian ZY, Rychik J (2005) Preliminary investigations into a new method of functional assessment of the fetal heart using a novel application of ‘real-time’ cardiac magnetic resonance imaging. Fetal Diagn Ther 20:475–480

    Article  PubMed  Google Scholar 

  • Glastonbury CM, Kennedy AM (2002) Ultrafast MRI of the fetus. Australas Radiol 46:22–32

    Article  PubMed  Google Scholar 

  • Gorincour G, Bourliere-Najean B, Bonello B, Fraisse A, Philip N, Potier A, Kreitmann B, Petit P (2007) Feasibility of fetal cardiac magnetic resonance imaging: preliminary experience. Ultrasound Obstet Gynecol 29:105–108

    Article  PubMed  CAS  Google Scholar 

  • Hata K, Hata T, Manabe A, Kitao M (1995) Hypoplastic left heart syndrome: color Doppler sonographic and magnetic resonance imaging features in utero. Gynecol Obstet Invest 39:70–72

    Article  PubMed  CAS  Google Scholar 

  • Huppert BJ, Brandt KR, Ramin KD, King BF (1999) Single-shot fast spin-echo MR imaging of the fetus: a pictorial essay. Radiographics 19(spec no):S215–S227

    Google Scholar 

  • Kachalia P, Bowie JD, Adams DB, Carroll BA (1991) In utero sonographic appearance of the atrial septum primum and septum secundum. J Ultrasound Med 10:423–426

    PubMed  CAS  Google Scholar 

  • Kiserud T, Rasmussen S (2001) Ultrasound assessment of the fetal foramen ovale. Ultrasound Obstet Gynecol 17:119–124

    Article  PubMed  CAS  Google Scholar 

  • Kivelitz DE, Mühler M, Rake A, Scheer I, Chaoui R (2004) MRI of cardiac rhabdomyoma in the fetus. Eur Radiol 14:1513–1516

    Article  PubMed  Google Scholar 

  • Levine D (2001) Ultrasound versus magnetic resonance imaging in fetal evaluation. Top Magn Reson Imaging 12:25–38

    Article  PubMed  CAS  Google Scholar 

  • Levine D, Barnes PD, Sher S, Semelka RC, Li W, McArdle CR, Worawattanakul S, Edelman RR (1998) Fetal fast MR imaging: reproducibility, technical quality, and conspicuity of anatomy. Radiology 206:549–554

    PubMed  CAS  Google Scholar 

  • Manganaro L, Savelli S, Di Maurizio M, Perrone A, Tesei J, Francioso A, Angeletti M, Coratella F, Irimia D, Fierro F, Ventriglia F, Ballesio L (2008) Potential role of fetal cardiac evaluation with magnetic resonance imaging: preliminary experience. Prenat Diagn 28:148–156

    Article  PubMed  Google Scholar 

  • Manganaro L, Savelli S, Di Maurizio M, Francioso A, Fierro F, Tomei A, Coratella F, Ballesio L, Ventriglia F (2009a) Fetal MRI of the cardiovascular system: role of steady-state free precession sequences for the evaluation of normal and pathological appearances. Radiol Med 114:852–870

    Article  PubMed  CAS  Google Scholar 

  • Manganaro L, Savelli S, Di Maurizio M, Perrone A, Francioso A, La Barbera L, Totaro P, Fierro F, Tomei A, Coratella F, Giancotti A, Ballesio L, Ventriglia F (2009b) Assessment of congenital heart disease (CHD): is there a role for fetal magnetic resonance imaging (MRI)? Eur J Radiol 72:172–180

    Article  PubMed  CAS  Google Scholar 

  • Mansfield P, Stehling MK, Ordidge RJ, Coxon R, Chapman B, Blamire A, Gibbs P, Johnson IR, Symonds EM, Worthington BS et al (1990) Echo planar imaging of the human fetus in utero at 0.5 T. Br J Radiol 63:833–841

    Article  PubMed  CAS  Google Scholar 

  • Maron BJ, Hutchins GM (1974) The development of the semilunar valves in the human heart. Am J Pathol 74:331–344

    PubMed  CAS  Google Scholar 

  • Mühler MR, Rake A, Schwabe M, Chaoui R, Heling KS, Planke C, Lembcke A, Fischer T, Kivelitz D (2004) Truncus arteriosus communis in a midtrimester fetus: comparison of prenatal ultrasound and MRI with postmortem MRI and autopsy. Eur Radiol 14:2120–2124

    Article  PubMed  Google Scholar 

  • Noback GJ, Rehman I (1941) The ductus arteriosus in the human fetus and newborn infant. Anat Rec 81:505–527

    Article  Google Scholar 

  • Oosthoek PW, Wenink AC, Vrolijk BC, Wisse LJ, DeRuiter MC, Poelmann RE, Gittenberger-de Groot AC (1998a) Development of the atrioventricular valve tension apparatus in the human heart. Anat Embryol (Berl) 198:317–329

    Article  CAS  Google Scholar 

  • Oosthoek PW, Wenink AC, Wisse LJ, Gittenberger-de Groot AC (1998b) Development of the papillary muscles of the mitral valve: morphogenetic background of parachute-like asymmetric mitral valves and other mitral valve anomalies. J Thorac Cardiovasc Surg 116:36–46

    Article  PubMed  CAS  Google Scholar 

  • Oyer CE, Sung CJ, Friedman R, Hansen K, Paepe MD, Pinar H, Singer DB (2004) Reference values for valve circumferences and ventricular wall thicknesses of fetal and neonatal hearts. Pediatr Dev Pathol 7:499–505

    Article  PubMed  Google Scholar 

  • Oyer CE, Sung CJ, Friedman R, Hansen K, Paepe MD, Pinar H, Singer DB (2005) Reference values for valve circumferences and ventricular wall thicknesses of fetal and neonatal hearts. Erratum Pediatr Dev Pathol 8:139–140

    Article  Google Scholar 

  • Patten BM, Sommerfeld WA, Paff GH (1929) Functional limitations of the foramen ovale in the human foetal heart. Anat Rec 44:165–178

    Article  Google Scholar 

  • Reiff H (1976) Zur funktionellen Anatomie der venösen Einstrombahn ins menschliche fetale Herz. Basic Res Cardiol 71:199–209

    Article  PubMed  CAS  Google Scholar 

  • Saleem SN (2008) Feasibility of MRI of the fetal heart with balanced steady-state free precession sequence along fetal body and cardiac planes. AJR Am J Roentgenol 191:1208–1215

    Article  PubMed  Google Scholar 

  • Savelli S, Di Maurizio M, Francioso A, La Barbera L, Totaro P, Tomei A, Fierro F, Coratella F, Irimia D, Manganaro L (2009) Fetal mid-muscular ventricular septal defect: role of fetal cardio-vascular evaluation with magnetic resonance (MR) imaging and MR-angiography. Eur J Radiol Extra 69:e101–e103

    Article  Google Scholar 

  • Shipp TD, Bromley B, Hornberger LK, Nadel A, Benacerraf BR (1995) Levorotation of the fetal cardiac axis: a clue for the presence of congenital heart disease. Obstet Gynecol 85:97–102

    Article  PubMed  CAS  Google Scholar 

  • Smith RS, Comstock CH, Kirk JS, Lee W (1995) Ultrasonographic left cardiac axis deviation: a marker for fetal anomalies. Obstet Gynecol 85:187–191

    Article  PubMed  CAS  Google Scholar 

  • St John Sutton MG, Raichlen JS, Reichek N, Huff DS (1984) Quantitative assessment of right and left ventricular growth in the human fetal heart: a pathoanatomic study. Circulation 70:935–941

    Article  PubMed  CAS  Google Scholar 

  • Szpinda M (2007) Morphometric study of the ascending aorta in human fetuses. Ann Anat 189:465–472

    Article  PubMed  Google Scholar 

  • Szpinda M, Brazis P, Elminowska-Wenda G, Wisniewski M (2006) Morphometric study of the aortic and great pulmonary arterial pathways in human foetuses. Ann Anat 188:25–31

    Article  PubMed  Google Scholar 

  • Szpinda M, Szwesta A, Szpinda E (2007) Morphometric study of the ductus arteriosus during human development. Ann Anat 189:47–52

    Article  PubMed  Google Scholar 

  • Tandler J (1913) Anatomie des Herzens. Gustav Fischer, Jena

    Google Scholar 

  • Trop I, Levine D (2001) Normal fetal anatomy as visualized with fast magnetic resonance imaging. Top Magn Reson Imaging 12:3–17

    Article  PubMed  CAS  Google Scholar 

  • Walmsley R, Monkhouse WS (1988) The heart of the newborn child: an anatomical study based upon transverse serial sections. J Anat 159:93–111

    PubMed  CAS  Google Scholar 

  • Yamamura J, Schnackenburg B, Kooijmann H, Frisch M, Hecher K, Adam G, Wedegärtner U (2009) High resolution MR imaging of the fetal heart with cardiac triggering: a feasibility study in the sheep fetus. European Journal of Radiology Extra 19:2383–2390

    Article  PubMed  Google Scholar 

  • Zielinsky P, Sallum M, Satler F, Gus EI, Nicoloso LH, Manica JL, Piccoli AL Jr (2004) Mobility of the septum primum does not depend on the foramen ovale diameter in normal fetuses. Arq Bras Cardiol 83:304–307

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Peter C. Brugger .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Brugger, P.C. (2010). MRI of the Fetal Heart. In: Prayer, D. (eds) Fetal MRI. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2010_20

Download citation

  • DOI: https://doi.org/10.1007/174_2010_20

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-73270-9

  • Online ISBN: 978-3-540-73271-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics