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Heart Failure pp 35–66Cite as

Comorbidities in Heart Failure

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 243))

Abstract

Comorbidities frequently accompany chronic heart failure (HF), contributing to increased morbidity and mortality, and an impaired quality of life. We describe the prevalence of several high-impact comorbidities in chronic HF patients and their impact on morbidity and mortality. Furthermore, we try to explain the underlying pathophysiological processes and the complex interaction between chronic HF and specific comorbidities. Although common risk factors are likely to contribute, it is reasonable to believe that factors associated with HF might cause other comorbidities and vice versa. Potential factors are inflammation, neurohormonal activation, and hemodynamic changes.

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Authors and Affiliations

  1. Department of Cardiology, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands

    Haye H. van der Wal, Vincent M. van Deursen, Peter van der Meer & Adriaan A. Voors

  2. Hanzeplein 1, 9713 GZ, Groningen, The Netherlands

    Adriaan A. Voors

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  1. Haye H. van der Wal
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  2. Vincent M. van Deursen
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  3. Peter van der Meer
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  4. Adriaan A. Voors
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Correspondence to Adriaan A. Voors .

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Editors and Affiliations

  1. Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover Klinik für Kardiologie und Angiologie, Hannover, Niedersachsen, Germany

    Johann Bauersachs

  2. Heart Institute, Stony Brook University , Stony Brook, New York, USA

    Javed Butler

  3. Heart and Lung Diseases, Bayer Pharma Aktiengesellschaft Heart and Lung Diseases, Wuppertal, Nordrhein-Westfalen, Germany

    Peter Sandner

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van der Wal, H.H., van Deursen, V.M., van der Meer, P., Voors, A.A. (2017). Comorbidities in Heart Failure. In: Bauersachs, J., Butler, J., Sandner, P. (eds) Heart Failure. Handbook of Experimental Pharmacology, vol 243. Springer, Cham. https://doi.org/10.1007/164_2017_27

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