Abstract
Coronary artery bypass grafting (CABG) gives the long-term patency of the conduit.
The left internal thoracic artery (ITA) is acknowledged as the best coronary conduit.
Harvesting the ITA(s) with a pedicled technique may potentially lead to significant sternal devascularization, while there is limited tissue mobilization associated with skeletonized ITA harvesting, and this preserves substantial collateral flow to the sternum by sparing sternal and intercostal branches that arise from the ITA as a common trunk. The authors discuss single versus bilateral internal thoracic artery and arterial revascularization trial (ART). It has been found that bilateral internal thoracic artery (BITA) grafting is associated with more superior long-term survival and has very little clinical difference compared to deep sternal wound infection (DSWI) with single ITA grafting.
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References
Loop FD, Lytle BW, Cosgrove DM, Stewart RW, Goormastic M, Williams GW, Golding LA, Gill CC, Taylor PC, Sheldon WC et al (1986) Influence of the internal-mammary-artery graft on 10-year survival and other cardiac events. N Engl J Med 314:1–6
Benedetto U, Raja SG, Albanese A, Amrani M, Biondi-Zoccai G, Frati G (2015) Searching for the second best graft for coronary artery bypass surgery: a network meta-analysis of randomized controlled trials. Eur J Cardiothorac Surg 47:59–65
Taggart DP, D’Amico R, Altman DG (2001) Effect of arterial revascularisation on survival: a systematic review of studies comparing bilateral and single internal mammary arteries. Lancet 358(9285):870–875
Yi G, Shine B, Rehman SM, Altman DG, Taggart DP (2014) Effect of bilateral internal mammary artery grafts on long-term survival: a meta-analysis approach. Circulation 130:539–545
Tabata M, Grab JD, Khalpey Z, Edwards FH, O’Brien SM, Cohn LH, Bolman RM 3rd (2009) Prevalence and variability of internal mammary artery graft use in contemporary multivessel coronary artery bypass graft surgery. Circulation 120:935–940
Catarino PA, Black E, Taggart DP (2002) Why do UK cardiac surgeons not perform their first choice operation for coronary artery bypass graft? Heart 88:643–644
Taggart DP, Altman DG, Gray AM, Lees B, Gerry S, Benedetto U, Flather M, Investigators ART (2016) Randomized trial of bilateral versus single internal-thoracic-artery grafts. N Engl J Med 375:2540–2549
Kamiya H, Akhyari P, Martens A, Karck M, Haverich A, Lichtenberg A (2008) Sternal microcirculation after skeletonized versus pedicled harvesting of the internal thoracic artery: a randomized study. J Thorac Cardiovasc Surg 135:32–37
Boodhwani M, Lam BK, Nathan HJ, Mesana TG, Ruel M, Zeng W, Sellke FW, Rubens FD (2006) Skeletonized internal thoracic artery harvest reduces pain and dysesthesia and improves sternal perfusion after coronary artery bypass surgery: a randomized, double blind, within-patient comparison. Circulation 114:766–773
Sa MP, Cavalcanti PE, de Andrade Costa Santos HJ, Soares AF, Albuquerque Miranda RG, Araujo ML, Lima RC (2015) Skeletonized versus pedicled bilateral internal mammary artery grafting: outcomes and concerns analyzed through a meta-analytical approach. Int J Surg 16(Pt B):146–152
Sa MP, Ferraz PE, Escobar RR, Vasconcelos FP, Ferraz AA, Braile DM, Lima RC (2013) Skeletonized versus pedicled internal thoracic artery and risk of sternal wound infection after coronary bypass surgery: meta-analysis and meta-regression of 4817 patients. Interact Cardiovasc Thorac Surg 16:849–857
Onorati F, Esposito A, Pezzo F, di Virgilio A, Mastroroberto P, Renzulli A (2007) Hospital outcome analysis after different techniques of left internal mammary grafts harvesting. Ann Thorac Surg 84:1912–1919
Raja SG, Dreyfus GD (2005) Internal thoracic artery: to skeletonize or not to skeletonize? Ann Thorac Surg 79:1805–1811
Benedetto U, Altman DG, Gerry S, Gray A, Lees B, Pawlaczyk R, Flather M, Taggart DP, Arterial Revascularization Trial investigators (2016) Pedicled and skeletonized single and bilateral internal thoracic artery grafts and the incidence of sternal wound complications: insights from the Arterial Revascularization Trial. J Thorac Cardiovasc Surg 152:270–276
Fitzgibbon GM, Kafka HP, Leach AJ, Keon WJ, Hooper GD, Burton JR (1996) Coronary bypass graft fate and patient outcome: angiographic follow-up of 5,065 grafts related to survival and reoperation in 1,388 patients during 25 years. J Am Coll Cardiol 28:616–626
Weintraub WS, Jones EL, Craver JM, Guyton RA (1994) Frequency of repeat coronary bypass or coronary angioplasty after CABG using saphenous vein grafts. Am J Cardiol 73:103–112
Gansera B, Schmidtler F, Angelis I, Kiask T, Kemkes BM, Botzenhardt F (2007) Patency of internal thoracic artery compared to vein grafts — postoperative angiographic findings in 1189 symptomatic patients in 12 years. Thorac Cardiovasc Surg 55:412–417
Takagi H, Goto SN, Watanabe T, Mizuno Y, Kawai N, Umemoto T (2014) A meta-analysis of adjusted hazard ratios from 20 observational studies of bilateral versus single internal thoracic artery coronary artery bypass grafting. J Thorac Cardiovasc Surg 148:1282–1290
Rizzoli G, Schiavon L, Bellini P (2002) Does the use of bilateral internal mammary artery (IMA) grafts provide incremental benefit relative to the use of a single IMA graft? A meta-analysis approach. Eur J Cardiothorac Surg 22:781–786
Weiss AJ, Zhao S, Tian DH, Taggart DP, TD Y (2013) A meta-analysis comparing bilateral internal mammary artery with left internal mammary artery for coronary artery bypass grafting. Ann Cardiothorac Surg 2:390–400
Bridgewater B, Keogh B, Kinsman R, Walton P Sixth National Adult Cardiac Surgical Database Report 2008. https://www.scts.org/_userfiles/resources/SixthNACSDreport2008withcovers.pdf. Accessed 19 Sep 2017
Gray AM, Murphy J, Altman DG, Benedetto U, Campbell H, Flather M, Gerry S, Lees B, Taggart DP (2017) One-year costs of bilateral or single internal mammary grafts in the Arterial Revascularisation Trial. Heart 103(21):1719–1726
Itagaki S, Cavallaro P, Adams DH, Chikwe J (2013) Bilateral internal mammary artery grafts, mortality and morbidity: an analysis of 1 526 360 coronary bypass operations. Heart 99:849–853
Benedetto U, Montecalvo A, Kattach H, Amrani M, Raja SG, Harefield Cardiac Outcomes Research Group (2015) Impact of the second internal thoracic artery on short- and long-term outcomes in obese patients: a propensity score matched analysis. J Thorac Cardiovasc Surg 149:841–847
Athanasiou T, Crossman MC, Asimakopoulos G, Cherian A, Weerasinghe A, Glenville B, Casula R (2004) Should the internal thoracic artery be skeletonized? Ann Thorac Surg 77:2238–2246
Buttar SN, Yan TD, Taggart DP, Tian DH (2017) Long-term and short-term outcomes of using bilateral internal mammary artery grafting versus left internal mammary artery grafting: a meta-analysis. Heart 103:1419–1426
Cho KR, Kim JS, Choi JS, Kim KB (2006) Serial angiographic follow-up of grafts one year and five years after coronary artery bypass surgery. Eur J Cardiothorac Surg 29:511–516
Wee CC, Girotra S, Weinstein AR, Mittleman MA, Mukamal KJ (2008) The relationship between obesity and atherosclerotic progression and prognosis among patients with coronary artery bypass grafts the effect of aggressive statin therapy. J Am Coll Cardiol 52:620–625
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Bridgeman, A., Benedetto, U. (2018). Pedicled and Skeletonized Single and Bilateral Internal Thoracic Artery Grafts and the Incidence of Sternal Wound Complications. In: Shiffman, M., Low, M. (eds) Vascular Surgery, Neurosurgery, Lower Extremity Ulcers, Antimicrobials, Wound Assessment, Care, Measurement and Repair. Recent Clinical Techniques, Results, and Research in Wounds, vol 5. Springer, Cham. https://doi.org/10.1007/15695_2018_129
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DOI: https://doi.org/10.1007/15695_2018_129
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