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Biofilm, Pilonidal Cysts and Sinuses pp 89–108Cite as

Antibiofilm Efficacy of Honeybee Products Against Wound Biofilm

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Part of the book series: Recent Clinical Techniques, Results, and Research in Wounds ((RCTRRW,volume 1))

Abstract

Treatment of bacterial biofilm in the wound is complicated by the mechanisms underlying biofilm growth. Many clinically relevant biofilms are polymicrobial. Furthermore, mixed species biofilms have complementary metabolic strategies for obtaining nutrients and degrading host immune molecules. Therefore, there is an urgent need to introduce novel or reemerging effective approaches to combat bacterial biofilms in chronic wounds.

Honeybee products such as honey, royal jelly, and propolis have been successfully used for treating chronic wounds associated with bacterial biofilms. One of the major benefits of these natural products is that there is no risk of developing antibacterial resistance.

This chapter discusses the current knowledge about antibacterial and antibiofilm activity of selected honeybee products and presents the experimental data from the testing of honey antibiofilm activity using multispecies Lubbock in vitro chronic wound biofilm model.

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Acknowledgments

We thank Mrs. Darina Majercikova for her technical help. This work was supported by the Scientific Grant Agency of the Ministry of Education of the Slovak Republic and the Slovak Academy of Sciences VEGA 2/0007/14.

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Authors and Affiliations

  1. Faculty of Medicine, Department of Microbiology, Slovak Medical University, Bratislava, Slovakia

    Martin Sojka, Miroslava Horniackova, Viktor Majtan & Juraj Majtan

  2. Laboratory of Apidology and Apitherapy, Institute of Molecular Biology, Slovak Academy of Sciences, Bratislava, Slovakia

    Marcela Bucekova & Juraj Majtan

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  1. Martin Sojka
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  2. Miroslava Horniackova
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  3. Marcela Bucekova
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  4. Viktor Majtan
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Correspondence to Juraj Majtan .

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  1. Tustin, CA, USA

    Melvin A. Shiffman

  2. Newport Beach, CA, USA

    Mervin Low

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Sojka, M., Horniackova, M., Bucekova, M., Majtan, V., Majtan, J. (2018). Antibiofilm Efficacy of Honeybee Products Against Wound Biofilm. In: Shiffman, M., Low, M. (eds) Biofilm, Pilonidal Cysts and Sinuses. Recent Clinical Techniques, Results, and Research in Wounds, vol 1. Springer, Cham. https://doi.org/10.1007/15695_2018_108

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