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Boston Type I Keratoprosthesis in Ocular Chemical Burns

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Book cover Plastic and Thoracic Surgery, Orthopedics and Ophthalmology

Part of the book series: Recent Clinical Techniques, Results, and Research in Wounds ((RCTRRW,volume 4))

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Abstract

Chemical burns may produce severe and extensive damage to the ocular surface. The authors discuss the various keratoplasties used for ocular chemical burns and the development of KPro. Contraindications to KPro are described with the procedure, the postoperative management, the outcomes, and the complications. KPro I implantation is a promising surgical modality in eyes with severe chemical burns. Good patient selection and in-depth patient follow-up have a critical impact on patient outcomes.

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References

  1. Sundmacher R, Reinhard T, Althaus C (1997) Homologous central limbo-keratoplasty in limbus stem cell damage. Retrospective study of 3 years’ experience. Ophthalmologe 94(12):897–901

    Article  CAS  PubMed  Google Scholar 

  2. Redbrake C, Buchal V (1996) Keratoplasty with scleral rim after the most severe chemical eye burns of the anterior eye segment. Klin Monatsbl Augenheilkd 208(3):145–151

    Article  CAS  PubMed  Google Scholar 

  3. Kramer SG (1983) Late numerical grading of alkali burns to determine keratoplasty prognosis. Trans Am Ophthalmol Soc 82:97–106

    Google Scholar 

  4. Mattax JB, McCulley JP (1988) Corneal surgery following alkali burns. Int Ophthalmol Clin 28(1):76–82

    Article  CAS  PubMed  Google Scholar 

  5. Tan DT, Ficker LA, Buckley RJ (1996) Limbal transplantation. Ophthalmology 103(1):29–36

    Article  CAS  PubMed  Google Scholar 

  6. Tims S, Lee B (2013) Keratoplasty in ocular surface disease. In: Holland EJ, Mannis MJ, Lee B (eds) Ocular surface disease. Elsevier, London, pp 397–402

    Google Scholar 

  7. Slegers T, Daly M, Larkin P (2006) Corneal transplant rejection. In: Reinhard T, Larkin D (eds) Cornea and external eye disease. Springer, Berlin, pp 73–81

    Chapter  Google Scholar 

  8. Hicks CR, Crawford GJ, Dart JK, Grabner G, Holland EJ, Stulting RD, Tan DT, Bulsara M (2006) AlphaCor: clinical outcomes. Cornea 25(9):1034–1042

    Article  PubMed  Google Scholar 

  9. De La Paz MF, De Toledo JÁ, Charoenrook V, Sel S, Temprano J, Barraquer RI, Michael R (2011) Impact of clinical factors on the long-term functional and anatomic outcomes of osteo-odonto-keratoprosthesis and tibial bone keratoprosthesis. Am J Ophthalmol 151(5):829–839

    Article  Google Scholar 

  10. Homayounfar G, Grassi CM, Al-Moujahed A, Colby KA, Dohlman CH, Chodosh J (2016) Type 1 Boston keratoprosthesis: outcomes at two Canadian centres. Can J Ophthalmol 51(2):76–82

    Article  Google Scholar 

  11. Dohlman CH, Schneider H, Doane MG (1974) Prosthokeratoplasty. Am J Ophthalmol 77:694–700

    Article  CAS  PubMed  Google Scholar 

  12. Ahmad S, Akpek E (2016) Comparing repeat donor corneal transplantation to boston keratoprosthesis in patients with previous graft failure. Boston KPro News 12:1–3

    Google Scholar 

  13. Lee R, Khoueir Z, Tsikata E, Chodosh J, Dohlman CH, Chen TC (2017) Long-term visual outcomes and complications of boston keratoprosthesis type II implantation. Ophthalmology 124(1):27–35

    Article  PubMed  Google Scholar 

  14. Gu J, Zhai J, Zhou S, Chen J (2016) Boston keratoprosthesis outcomes in severe ocular chemical burns in southern China: a retrospective study. Adv Ther 33(5):760–773

    Article  CAS  PubMed  Google Scholar 

  15. Cade F, Grosskreutz CL, Tauber A, Dohlman CH (2011) Glaucoma in eyes with severe chemical burn, before and after keratoprosthesis. Cornea 30(12):1322–1327

    Article  PubMed  Google Scholar 

  16. Magalhães FP, Hirai FE, de Sousa LB, de Oliveira LA (2013) Boston type 1 keratoprosthesis outcomes in ocular burns. Acta Ophthalmol 91(6):e432–e436

    Article  PubMed  Google Scholar 

  17. Phillips DL, Hager JL, Goins KM, Kitzmann AS, Greiner MA, Cohen AW, Welder JD, Wagoner MD (2014) Boston type 1 keratoprosthesis for chemical and thermal injury. Cornea 33(9):905–909

    Article  PubMed  Google Scholar 

  18. Harissi-Dagher M, Dohlman CH (2008) The Boston Keratoprosthesis in severe ocular trauma. Can J Ophthalmol 43(2):165–169

    Article  PubMed  Google Scholar 

  19. Salvador-Culla B, Kolovou PE (2016) Keratoprosthesis: a review of recent advances in the field. J Funct Biomater 7(2):13

    Article  PubMed Central  Google Scholar 

  20. Todani A, Ciolino JB, Ament JD, Colby KA, Pineda R, Belin MW, Aquavella JV, Chodosh J, Dohlman CH (2011) Titanium back plate for a PMMA keratoprosthesis: clinical outcomes. Graefes Arch Clin Exp Ophthalmol 249(10):1515–1518

    Article  CAS  PubMed  Google Scholar 

  21. Ray S, Khan BF, Dohlman CH, D’Amico DJ (2002) Management of vitreoretinal complications in eyes with permanent keratoprosthesis. Arch Ophthalmol 120(5):559–566

    Article  PubMed  Google Scholar 

  22. Dohlman CH (1983) Biology of complications following Keratoprosthesis. Cornea 2(3):175–176

    Article  Google Scholar 

  23. Hannush SB (2011) Postoperative management of keratoprosthesis. In: Krachmer JH, Mannis MJ, Holland EJ (eds) Cornea, 3rd edn. Mosby Elsevier, St. Louis, MO, pp 1699–1704

    Chapter  Google Scholar 

  24. Al-Merjan J, Sadeq N, Dohlman CH (2000) Temporary tissue coverage of keratoprosthesis. Mid East Afr J Ophthalmol 8:12

    Google Scholar 

  25. Dohlman CH (2016) Total conjunctival flap in KPro surgery. Boston KPro news, XII 2016. Massachusetts Eye and Ear Infirmary

    Google Scholar 

  26. Sivaraman KR, Hou JH, Allemann N, de la Cruz J, Cortina MS (2013) Retroprosthetic membrane and risk of sterile keratolysis in patients with type I Boston Keratoprosthesis. Am J Ophthalmol 155(5):814–822

    Article  PubMed  Google Scholar 

  27. Paterson CA, Pfister RR (1973) Ocular hypertensive response to alkali burns in the monkey. Exp Eye Res 17(5):449–453

    Article  CAS  PubMed  Google Scholar 

  28. Fish R, Davidson RS (2010) Management of ocular thermal and chemical injuries, including amniotic membrane therapy. Curr Opin Ophthalmol 21(4):317–321

    PubMed  Google Scholar 

  29. Dohlman CH, Cade F, Pfister R (2011) Chemical burns to the eye: paradigm shifts in treatment. Cornea 30(6):613–614

    Article  PubMed  Google Scholar 

  30. P N, Chopra V (2014) Glaucoma management in Boston keratoprosthesis type I recipients. Curr Opin Ophthalmol 25(2):134–140

    Article  Google Scholar 

  31. Rivier D, Paula JS, Kim E, Dohlman CH, Grosskreutz CL (2009) Glaucoma and keratoprosthesis surgery: role of adjunctive cyclophotocoagulation. J Glaucoma 18(4):321

    Article  PubMed  Google Scholar 

  32. de Oliveira LA, Pedreira Magalhães F, Hirai FE, de Sousa LB (2014) Experience with Boston keratoprosthesis type 1 in the developing world. Can J Ophthalmol 49(4):351–357

    Article  PubMed  Google Scholar 

  33. Goldman DR, Hubschman JP, Aldave AJ, Chiang A, Huang JS, Bourges JL, Schwartz SD (2013) Postoperative posterior segment complications in eyes treated with the Boston type I keratoprosthesis. Retina 33(3):532–541

    Article  PubMed  Google Scholar 

  34. Ilsar M, Chirambo M, Belkin M (1982) Ocular injuries in Malawi. Br J Ophthalmol 66(2):145–148

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  35. Umeh RE, Umeh OC (1997) Causes and visual outcome of childhood eye injuries in Nigeria. Eye (Lond) 11(Pt 4):489–495

    Article  Google Scholar 

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Authors and Affiliations

  1. Cornea Service, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, People’s Republic of China

    Jiaqi Chen M.D., Jianjun Gu & Jiajie Zhai

Authors
  1. Jiaqi Chen M.D.
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  2. Jianjun Gu
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  3. Jiajie Zhai
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Corresponding author

Correspondence to Jiaqi Chen M.D. .

Editor information

Editors and Affiliations

  1. Tustin, CA, USA

    Melvin A. Shiffman

  2. Newport Beach, CA, USA

    Mervin Low

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Chen, J., Gu, J., Zhai, J. (2018). Boston Type I Keratoprosthesis in Ocular Chemical Burns. In: Shiffman, M., Low, M. (eds) Plastic and Thoracic Surgery, Orthopedics and Ophthalmology. Recent Clinical Techniques, Results, and Research in Wounds, vol 4. Springer, Cham. https://doi.org/10.1007/15695_2017_67

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  • DOI: https://doi.org/10.1007/15695_2017_67

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-10709-3

  • Online ISBN: 978-3-030-10710-9

  • eBook Packages: MedicineMedicine (R0)

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