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Pressure Injury, Diabetes and Negative Pressure Wound Therapy pp 303–308Cite as

Use of Negative-Pressure Wound Therapy on Malignant Wounds

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Part of the book series: Recent Clinical Techniques, Results, and Research in Wounds ((RCTRRW,volume 3))

Abstract

The use of negative-pressure wound therapy (NPWT) is traditionally contraindicated in malignant wounds due to concerns that it may promote tumorigenesis and expedite metastasis. However this belief is largely derived from studies on normal tissue and no literature directly supports the hypothesis that NPWT modulates oncological progression. Several studies reported the use of this technology in malignancy for palliative purposes with satisfactory outcome. Most recently, our own experience demonstrated successful closure of malignant wounds with the assistance of NPWT and no overt tumor progression on follow-up. These cases, as well as others in the literature, demonstrated that use of NPWT should not be considered an absolute contraindication in malignancy. Individualized approaches taking into account the patient’s clinical scenario, the available evidence, as well as the risks and benefits of this technology are recommended.

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Authors and Affiliations

  1. Department of Plastic Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA

    Yvonne M. Rasko M.D. & Stephen S. Cai M.D.

  2. Department of Plastic, Reconstructive, and Maxillofacial Surgery, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD, 21201, USA

    Silviu C. Diaconu

Authors
  1. Yvonne M. Rasko M.D.
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  2. Stephen S. Cai M.D.
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  3. Silviu C. Diaconu
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Corresponding author

Correspondence to Yvonne M. Rasko M.D. .

Editor information

Editors and Affiliations

  1. Tustin, CA, USA

    Melvin A. Shiffman

  2. Newport Beach, CA, USA

    Mervin Low

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Rasko, Y.M., Cai, S.S., Diaconu, S.C. (2018). Use of Negative-Pressure Wound Therapy on Malignant Wounds. In: Shiffman, M., Low, M. (eds) Pressure Injury, Diabetes and Negative Pressure Wound Therapy. Recent Clinical Techniques, Results, and Research in Wounds, vol 3. Springer, Cham. https://doi.org/10.1007/15695_2017_59

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  • DOI: https://doi.org/10.1007/15695_2017_59

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-10700-0

  • Online ISBN: 978-3-030-10701-7

  • eBook Packages: MedicineMedicine (R0)

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