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Poly(lactic acid) Controlled Drug Delivery

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Industrial Applications of Poly(lactic acid)

Part of the book series: Advances in Polymer Science ((POLYMER,volume 282))

Abstract

Various drug delivery systems are being rapidly developed for controlled drug release, improved efficacy, and reduced side effects with the goal of improving quality of life for patients and curing disease. Poly(lactic acid) (PLA) possesses numerous advantages compared with other polymers, including biocompatibility, biodegradability, low cost, environmental friendliness, and easily modified mechanical properties. These properties make PLA a promising polymer for biomedical applications. This review introduces the specific characteristics of PLA that enable its application for controlled drug delivery and describes different forms of PLA used for drug delivery, including nanoparticles, microspheres, hydrogels, electrospun fibers, and scaffolds. Previous work is summarized and future development is discussed.

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Authors and Affiliations

  1. Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun, 130022, People’s Republic of China

    Jiannan Li, Jianxun Ding & Xuesi Chen

  2. Department of General Surgery, The Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China

    Jiannan Li & Tongjun Liu

  3. Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104-6321, USA

    Jessica F. Liu & Lesan Yan

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  1. Jiannan Li
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  2. Jianxun Ding
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  3. Tongjun Liu
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  4. Jessica F. Liu
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  5. Lesan Yan
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  6. Xuesi Chen
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Correspondence to Jianxun Ding .

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  1. National Research Council, Institute of Polymers, Composites and Biomaterials, Pozzuoli, Italy

    Maria Laura Di Lorenzo

  2. Interdisciplinary Center for Transfer-Oriented Research in Natural Sciences, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany

    René Androsch

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Li, J., Ding, J., Liu, T., Liu, J.F., Yan, L., Chen, X. (2017). Poly(lactic acid) Controlled Drug Delivery. In: Di Lorenzo, M., Androsch, R. (eds) Industrial Applications of Poly(lactic acid). Advances in Polymer Science, vol 282. Springer, Cham. https://doi.org/10.1007/12_2017_11

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