Metal-Catalyzed Multicomponent Reactions for the Synthesis of Polymers

  • Ryohei KakuchiEmail author
Part of the Advances in Polymer Science book series (POLYMER, volume 269)


Despite the chemical complexity of multicomponent reactions (MCRs), the dawn of MCRs was fairly early in the history of organic chemistry. After lagging behind successful utilization of MCRs in combinatorial chemistry, the integration of MCRs with polymer chemistry has very recently started, which offers new possibilities in polymer synthesis. In spite of a large number of MCRs available for organic transformation reactions, this chapter describes metal-catalyzed MCRs in the area of polymer chemistry.


Multicomponent reactions Organometallic catalysts Polymer synthesis 



Metal-catalyzed three-component reactions between alkynes, amines, and aldehydes


Cu(I)-catalyzed cycloaddition reaction between terminal alkynes and azides


Cu(I)-catalyzed multicomponent reaction between terminal alkynes, sulfonyl azides, and nucleophiles


Sequential Cu(I)-catalyzed cycloaddition reaction between alkynes and azides and metal-catalyzed cross-coupling reaction of triazole derivatives


Isocyanide-based multicomponent reaction


Metal-catalyzed multicomponent reaction


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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  1. 1.Faculty of Natural System, Institute of Science and EngineeringKanazawa UniversityKanazawaJapan

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